The disruption of <i>S</i>. <i>praecaptivus</i> quorum sensing (QS) genes decreases tsetse survival upon infection. by Miguel Medina Munoz (9243611)

MCP-1-deficiency decreased CD11c-expressing cells via impairing the production of ROS and decreased activation of PLCγ2, Akt, and ERK upon M-CSF stimulation in BMM. by Woon-Ki Kim (447798)

“…<p>BMMs from WT (open bar) and MCP-1-KO mice (oblique-lined bar) were incubated in the presence of M-CSF (30 ng/ml) with U73122 (10 µM), Akt inhibitor IV (0.3 µM), PD098059 (5 µM), DPI (50 nM), NAC (3 mM), or H₂O₂ (300 µM) for 4 d (A). *, <i>P</i><0.05; ***, <i>P</i><0.001 compared with vehicle-treated WT cells. …”

Ly49C peptide dependent recognition of H-2K^b decreases with peptides bearing non-polar aliphatic auxiliary anchor residues. by Elsa A. Marquez (766160)

Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology by Laurence J. Howe (5579186)

“…Where evidence was found of genetic overlap, we used bidirectional Mendelian randomization (MR) to test the hypothesis that genetic liability to nsCL/P is causally related to implicated facial phenotypes. Across 5,804 individuals of European ancestry from two studies, we found strong evidence, using PRS, of genetic overlap between nsCL/P and philtrum width; a 1 S.D. increase in nsCL/P PRS was associated with a 0.10 mm decrease in philtrum width (95% C.I. 0.054, 0.146; P = 2x10^-5). …”

GCase substrate levels are altered in the brain and liver of homozygous <i>GBA1</i> D409V KI mice. by Nicole K. Polinski (10947787)

NRF2-mediated oxidative stress genes differentially expressed in liver of <i>Fmo5</i>^<i>-/-</i> mice compared with WT mice. by Ian R. Phillips (5074121)

Tim-3 deficiency enhances the levels of proinflammatory cytokines and decreases the parasite burden. by Houbao Qi (11996039)

Lysosome function, as assessed by Lamp1 levels, are unchanged in the <i>GBA1</i> D409V KI mouse model. by Nicole K. Polinski (10947787)

Dopamine turnover, but not total dopamine levels or nigral dopamine neuron numbers, are altered in aged homozygous <i>GBA1</i> D409V KI mice as compared to controls. by Nicole K. Polinski (10947787)

Mean decrease in accuracy (MDA) of top 15 urine metabolites. by Liam E. Broughton-Neiswanger (8447220)

“…Urine metabolites with a mean decrease in accuracy ≥ 0.004 in at least one post-treatment time point (2–5) were considered for inclusion in the predictive model.…”

Decrease of GFP-TbAtg8 fluorescence during starvation. by Remo S. Schmidt (546946)

Cell surface CHT levels are unchanged by altered PI3-Kinase signaling in non-depolarized cells. by Katherine J. Fishwick (768451)

Telmisartan decreased NO production in LPS-stimulated BV2 and primary neonatal rat glial cells. by Nofar Torika (3169497)

Mfsd2a KO mice have decreased liver TG with normal liver metabolism. by Justin H. Berger (297156)

Reduced EGFR signaling leads to decreased survivin expression in islets during pregnancy in mice. by Elina Hakonen (545991)

Decreased MBP levels in the brain in <i>Large</i>^{<i>myd/myd</i>} mice. by Shigefumi Morioka (8893511)

“…<b>B,</b> Whole-brain lysates of P7 control and <i>Large</i>^{<i>myd/myd</i>} mice (<i>n</i> = 5) were obtained for MBP immunoblotting. Decreased expression levels of MBP were observed in <i>Large</i>^{<i>myd/myd</i>} mice compared with those in control mice. …”

Loss of nsp14-ExoN activity decreases recombination frequency and alters recombination junction patterns across the genome. by Jennifer Gribble (10005444)

TIRF analyses of pericentrin-depleted MIN6 cells at non-stimulatory glucose concentration (2.5 mM) show increase in docked insulin granules and decrease at stimulatory glucose concentration (25 mM). by Agata Jurczyk (245201)

Antidepressants decrease β-catenin-induced liver enlargement and tumorigenesis. by Kimberley J. Evason (764570)

Pneumococci decrease epithelial surface fluid flow and particle transport. by Manfred Fliegauf (391677)