Movie 2 Rik^null vs. WT. by Erdyni N. Tsitsikov (20384719)

Human disease-causing mutations in <i>LMOD2</i> result in a decrease in mature, but not pre-, mRNA levels when expressed from a construct containing a downstream intron, which is a... by Christopher T. Pappas (8218833)

A genetic deficit in endothelial c-kit expression decreases colony-forming VESCs and results in impaired EC proliferation and angiogenesis, and retardation of tumor growth in vivo. by Shentong Fang (127331)

Mitotic entry was delayed in ULK1-KO, ATG7/ATG9A-KO but not K46I kinase-dead ULK1 cell lines. by Zhiyuan Li (205620)

“…HeLa WT or ULK1-KO cells synchronized into mitosis released from thymidine for 5 hours and nocodazole for another 7 hours were subjected to either PI and pH3(S10) co-staining for cell cycle and mitotic index analysis by flow cytometry (A) or western blot analysis for cell cycle markers (B). …”

Figure 6. The 4D5 transposon mutant has decreased virulence in G. mellonella by Shauna McGillivray (7381679)

BRET² measurement of Gα_qβ₁γ₂ complex activation in HEK293 living cells expressing equal amounts of the WT of human TP receptor or its E1... by Valérie Capra (396007)

“…Agonist-induced coupling of TP receptor and Gq protein distances Gα_q-Rluc8 and GFP¹⁰-Gγ₂ giving rise to a decrease in the BRET signal. B. Protein expression levels of the constructs used for BRET experiments were set to be constant and able to assure the same level of basal BRET ratio in the presence of WT and E129V mutant of the human TP receptors. …”

Alteration of surface receptor expression in MØ obtained from WT and FcγRIa^−/− mice upon infection with <i>E. coli</i> K1. by Rahul Mittal (202639)

“…(B) The production of NO by MØ infected with <i>E. coli</i> K1 isolated from WT and FcγRIa^−/− mice was measured as nitrite by the Griess method. …”

Expression of the <i>PHO5</i> AS-blocking CRISPRi system leads to faster gene expression kinetics in wt and <i>rrp6Δ</i>, but not in <i>rpd3Δ</i> and <i>rpd3Δ rrp6Δ</i> double muta... by Ana Novačić (8373573)

Role of NOS isoforms in VEGF overexpressed lung on the vascular markers CD31 and vWF. by Mansoor A. Syed (847484)

“…<p>VEGF TG-, VEGF TG+, VEGF-TG/ NOS2^−/− and VEGF-TG/ NOS3^+/− mice exposed to DOX water from PN1-PN7. (<b>A</b> and <b>B</b>) Increased expression of lung CD31 in VEGF TG+ PN7 newborn mice, which was significantly decreased in VEGF-TG+/ NOS2^−/− and VEGF-TG/ NOS3^+/− (<b>C</b> and <b>D</b>) mice lungs. …”

Increase of proliferating progenitor cells and decrease of terminally differentiated granule neurons in the immature dentate gyrus of <i>PC3/Tis21</i>-null mice at P14. by Stefano Farioli-Vecchioli (256006)

“…<p>(<b>A</b>) The whole population of progenitor cells entering in S-phase, labeled by a short pulse of BrdU (1hour) and by the progenitor cell marker Sox2 (BrdU/Sox2-positive), increased significantly in <i>PC3/Tis21</i>-null mice (1.6-fold). …”

TG mice hearts show decreased ISO response. by Mayilvahanan Shanmugam (691549)

Scotopic b-wave characteristic in WT and <i>Fmr1</i> KO mice. by Rafaëlle Rossignol (621196)

“…<p>Retinal function was evaluated using ElectroRetinoGram (ERG). (<b>A</b>) Serial responses to increasing flash stimuli (−3.47 log(cd.s.m⁻²) to 0.6 log(cd.s.m⁻²)) were obtained for WT and <i>Fmr1</i> KO mice under dark-adapted conditions (n = 20 for WT and n = 17 for <i>Fmr1</i> KO). …”

(A) Phosphorylation of GIV is decreased upon depletion of Gαi3 (Gαi3 siRNA) and restored upon transfecting rGαi3 (Gαi3 siRNA and rGαi3) by Pradipta Ghosh (52052)

General motor activity of WT and <i>rSey²/+</i> rats in an open-field test. by Toshiko Umeda (358618)

“…<i>rSey²/+</i> rats exhibited decrease in the number of rearing compared to WT (genotype: F(1) = 6.54, P<0.02; time: F(5) = 17.13, P<0.001; genotype × time: F(5) = 3.74, P<0.005; <b>D</b>), although time spent in locomotion (<b>A</b>), distance of locomotion (<b>B</b>), and speed of movement (<b>C</b>) were not significantly changed. …”

METTL10 tri-methylates K318 in EF1A1. by Tadahiro Shimazu (619411)

Microarray-based comparative transcriptomic analysis of Δ<i>hp0197</i> and WT strains. by Anding Zhang (117904)

“…<p>(<b>A</b>) Microarray-based comparative transcriptomic analysis of Δ<i>hp0197</i> and WT strains. …”

Macrophages harvested <i>ex-vivo</i> from LZD treated mice have decreased expression of TNF-α as compared to saline treated animals post bacterial challenge. by Urvashi Bhan (247436)

<i>LacZ</i> expression pattern in <i>Ifitm1^tm1IEG/wt</i> embryos from E8.5 to E11.5. by Ingeborg Klymiuk (125310)

“…<p>(<b>A – E</b>) At E8.5 strong expression was found in the future brain and the neural tube. …”

Knockout or inhibition of CCR1 decreases peritoneal inflammation and CAIA. by Nuruddeen D. Lewis (192385)

ApoA-I inhibits leukocyte adhesion to endothelial cells <i>in vivo</i>. by Scott J. Cameron (838315)

“…(B) ApoA-I knockout mice (apoA-I ^-/-) have low plasma HDL concentration compared to WT mice and show increased adhesion of leukocytes to the vascular endothelium <i>in vivo</i> (decreased rolling velocity) compared to WT mice or apoA-I ^-/- mice injected with apo-AI (0.5mg, intraperitoneal) 24 hours before. …”