Showing 621 - 640 results of 104,500 for search '(( 1 wt decrease ) OR ( 5 ((point decrease) OR (((nn decrease) OR (a decrease)))) ))', query time: 1.60s Refine Results
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    Population dynamics modeling of split<sup>50cM</sup> <i>ClvR</i> V1 drive introduced at different release percentages, and an example illustrating the role that LOF alleles play in... by Georg Oberhofer (3401438)

    Published 2021
    “…(<b>G-I)</b> One way to appreciate the power of the latent drive force provided by LOF alleles that segregate independently of the <i>Rescue</i>/Cargo is to consider a split<sup>50cM</sup> <i>ClvR</i> population in which a <i>Rescue</i>/Cargo/gRNAs with no fitness cost has spread to allele fixation, the Cas9 driver chromosome has been completely eliminated (as would happen during drive if the presence of Cas9 resulted in a fitness cost to carriers, discussed below), and all endogenous copies of the essential gene have been rendered LOF (generation 0 in <b>G-I</b>). …”
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    Inclusion of SRRM4-regulated exons is decreased in tumors and cancer cell lines. by Sarah A. Head (6066398)

    Published 2021
    “…(B) SRRM4 target exons with respect to their average PSI in normal tissues. Red points are exons with PSI decreasing by at least 5% in at least 1 tumor type. …”
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    Loss of virulence in the SIN kinase mutants is characterized by decreased fungal burden and host response to infection. by Ana Camila Oliveira Souza (8180958)

    Published 2021
    “…**p = 0.0024 for (B); **p = 0.0031 for (C). An <i>in vitro</i> IL-1β release assay uncovered decreased induction of inflammasome activation by the SIN kinase mutants. …”
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    Decrease in number of activated macrophages in demyelinated nerves subjected to 1hr ES. by Nikki A. McLean (643606)

    Published 2014
    “…Note: ES results in a significant decrease in the ED-1 IF 10d post-LPC (5d post-ES; K) and 12d post-LPC (7d post-ES; N) relative to LPC only in a pattern suggestive of movement toward lateral edges and egress (arrow). …”
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    Effects of testosterone and isoproterenol on the WT and mutant LTCC. by Xin Liu (43569)

    Published 2017
    “…<p>(A-B) The representative whole-cell Ca2+ current traces and average current-voltage relationship show a decrease in current density in both the WT (n = 6) and Q1916R (n = 8) LTCC after treatment with testosterone (*<i>P</i><0.05, Q1916R or WT+tes <i>versus</i> WT-vehicle; #<i>P</i><0.05, Q1916R+tes <i>versus</i> Q1916R-vehicle). …”
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    Expression of pro-fibrotic genes of the TGFβ family is substantially decreased following AT1 receptor antagonism. by Anne-Cécile Huby (5653777)

    Published 2013
    “…Note that the increased expression of pro-fibrotic genes in RenTg mice was decreased to normal levels following treatment with the AT1 receptor antagonist. …”
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    CD43<sup>-/-</sup> septic mice exhibit decreased frequencies of apoptotic CD4<sup>+</sup> and CD8<sup>+</sup> naïve T cells as compared to WT septic mice. by Katherine T. Fay (2576998)

    Published 2018
    “…B) CD43<sup>-/-</sup> septic mice exhibited a decreased frequency of apoptotic naïve CD4<sup>+</sup> T cells, defined as 7-AAD<sup>+</sup> Annexin V<sup>+</sup> CD44<sup>LO</sup> CD62L<sup>HI</sup> CD4<sup>+</sup> cells, compared to WT septic mice (11.8±1.6 vs 18.8±1.3, p = 0.002. …”
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