Impact of water column attenuation on achromatic contrast (Δ<i>S</i>_<i>AC</i>) to fish (A) and bird (B) models. حسب Brandon J. Russell (793587)

"…Dashed line represents a ratio of 1 (no change). Decrease in achromatic contrast was generally low, except for the avian predator under the 5 m conditions, where median Δ<i>S</i>_<i>AC</i> of both species decreased by 15% and up to 50% for some individuals. …"

Inflammasome-dependent Pyroptosis and IL-18 Protect against <em>Burkholderia pseudomallei</em> Lung Infection while IL-1β Is Deleterious حسب Ivonne Ceballos-Olvera (84790)

"…The heightened susceptibility of <em>Nlrp3^-/-</em> mice was due to decreased production of IL-18 and IL-1β. In contrast, <em>Nlrc4^-/-</em> mice produced IL-1β and IL-18 in higher amount than WT mice and their high susceptibility was due to decreased pyroptosis and consequently higher bacterial burdens. …"

The effects of endolysin genes deletion on the production of ExPEC EVs. حسب Min Jiang (56794)

Image1_Multi-omics analyses reveal ClpP activators disrupt essential mitochondrial pathways in triple-negative breast cancer.jpg حسب Emily M. J. Fennell (6654536)

"…We performed a large-scale transcriptomic analysis of WT SUM159 cells, identifying ∼7,700 transcripts (746 and 1,100 significantly increasing, 795 and 1,013 significantly decreasing in ONC201 and TR-57 treated cells, respectively). …"

DataSheet_1_Association between dietary antioxidant levels and chronic obstructive pulmonary disease: a mediation analysis of inflammatory factors.docx حسب Ziyi Liu (1540222)

"…</p>Results<p>This study included 8257 participants (4111 women [weighted, 50.7%]; mean [SD] age, 58.8 [11.2] years). In a multivariable-adjusted model of single antioxidant intake, a linear downward association between carotenoid intake and the incidence of COPD (P for trend = 0.052; Pnon- linear = 0.961). …"

Table_1_Characteristics of second primary breast cancer after ovarian cancer: a Korea central cancer registry retrospective study.docx حسب Eun-Gyeong Lee (627417)

"…</p>Results<p>Among the 228,329 patients included, 228,148 were patients with PBC, and 181 patients had SPBC diagnosed after ovarian cancer (OC). The mean ages at diagnosis were 56.09 ± 10.81 years for SPBC and 50.65 ± 11.40 years for PBC. …"

Image1_Human engineered cardiac tissue model of hypertrophic cardiomyopathy recapitulates key hallmarks of the disease and the effect of chronic mavacamten treatment.TIF حسب Kai Wang (21246)

"…We found that chronic mavacamten treatment of R403Q ECTs: (i) shortened relaxation time, (ii) reduced APD₉₀ prolongation, (iii) upregulated ADRB2, ATP2A2, RYR2, and CACNA1C, (iv) decreased B-type natriuretic peptide (BNP) mRNA and protein expression levels, and (v) increased sarcomere length and reduced sarcomere disarray.…"

Image1_Human engineered cardiac tissue model of hypertrophic cardiomyopathy recapitulates key hallmarks of the disease and the effect of chronic mavacamten treatment.TIF حسب Kai Wang (21246)

"…We found that chronic mavacamten treatment of R403Q ECTs: (i) shortened relaxation time, (ii) reduced APD₉₀ prolongation, (iii) upregulated ADRB2, ATP2A2, RYR2, and CACNA1C, (iv) decreased B-type natriuretic peptide (BNP) mRNA and protein expression levels, and (v) increased sarcomere length and reduced sarcomere disarray.…"

Table1_Human engineered cardiac tissue model of hypertrophic cardiomyopathy recapitulates key hallmarks of the disease and the effect of chronic mavacamten treatment.DOCX حسب Kai Wang (21246)

"…We found that chronic mavacamten treatment of R403Q ECTs: (i) shortened relaxation time, (ii) reduced APD₉₀ prolongation, (iii) upregulated ADRB2, ATP2A2, RYR2, and CACNA1C, (iv) decreased B-type natriuretic peptide (BNP) mRNA and protein expression levels, and (v) increased sarcomere length and reduced sarcomere disarray.…"

Table1_Human engineered cardiac tissue model of hypertrophic cardiomyopathy recapitulates key hallmarks of the disease and the effect of chronic mavacamten treatment.DOCX حسب Kai Wang (21246)

"…We found that chronic mavacamten treatment of R403Q ECTs: (i) shortened relaxation time, (ii) reduced APD₉₀ prolongation, (iii) upregulated ADRB2, ATP2A2, RYR2, and CACNA1C, (iv) decreased B-type natriuretic peptide (BNP) mRNA and protein expression levels, and (v) increased sarcomere length and reduced sarcomere disarray.…"

<em>HRS1</em> Acts as a Negative Regulator of Abscisic Acid Signaling to Promote Timely Germination of <em>Arabidopsis</em> Seeds حسب Chongming Wu (169161)

"…Interestingly, the germination rate of <em>hrs1-1</em> was more severely reduced by the inhibitor of cell elongation, and more significantly decreased by the suppressors of plasmalemma H⁺-ATPase activity, than that of WT control. …"

Deep neural network reliably determines the emitter's sex from individual vocalizations. حسب A. Ivanenko (9010331)

"…Correspondingly the change in the network's weights (light red) progressively decreased after stabilizing after ~6k iterations. Data shown for a representative training run. …"

Table_1_The Rapid Population Collapse of a Key Marine Predator in the Northern Antarctic Peninsula Endangers Genetic Diversity and Resilience to Climate Change.docx حسب Douglas J. Krause (4630831)

"…To update the population status of SSI AFS, we analyzed 20 years of field-based data including population counts, body size and condition, natality, recruitment, foraging behaviors, return rates, and pup mortality at the largest SSI colony. Our findings show a precipitous decline in AFS abundance (86% decrease since 2007), likely driven by leopard seal predation (increasing since 2001, p << 0.001) and potentially worsening summer foraging conditions. …"

Human F₁F₀ ATP Synthase, Mitochondrial Ultrastructure and OXPHOS Impairment: A (Super-)Complex Matter? حسب Johann Habersetzer (385365)

"…We report here that in mammalian cells in culture, the shRNA-mediated down-regulation of subunits <i>e</i> and <i>g</i> affects the stability of ATP synthase and results in a 50% decrease of the available functional enzyme. …"

Table_2_The Rapid Population Collapse of a Key Marine Predator in the Northern Antarctic Peninsula Endangers Genetic Diversity and Resilience to Climate Change.csv حسب Douglas J. Krause (4630831)

"…To update the population status of SSI AFS, we analyzed 20 years of field-based data including population counts, body size and condition, natality, recruitment, foraging behaviors, return rates, and pup mortality at the largest SSI colony. Our findings show a precipitous decline in AFS abundance (86% decrease since 2007), likely driven by leopard seal predation (increasing since 2001, p << 0.001) and potentially worsening summer foraging conditions. …"

Table_1_Chronic Microglial Activation in the GFAP-IL6 Mouse Contributes to Age-Dependent Cerebellar Volume Loss and Impairment in Motor Function.DOCX حسب Erika Gyengesi (6549689)

"…In addition, TNF-α levels proved to be significantly higher in the GFAP-IL6 compared to WT mice at all time points. A difference in cerebellar volume between the GFAP-IL6 and WT mice was observed later in life, starting at 6 months and increasing to a loss of about 50% in aged (24 months old) GFAP-IL6 mice. …"

Image_1_Chronic Microglial Activation in the GFAP-IL6 Mouse Contributes to Age-Dependent Cerebellar Volume Loss and Impairment in Motor Function.tif حسب Erika Gyengesi (6549689)

"…In addition, TNF-α levels proved to be significantly higher in the GFAP-IL6 compared to WT mice at all time points. A difference in cerebellar volume between the GFAP-IL6 and WT mice was observed later in life, starting at 6 months and increasing to a loss of about 50% in aged (24 months old) GFAP-IL6 mice. …"

Image_1_NOD2 Deficiency Promotes Intestinal CD4+ T Lymphocyte Imbalance, Metainflammation, and Aggravates Type 2 Diabetes in Murine Model.jpeg حسب Daniela Carlos (68779)

"…Notably, the deficiency of NOD2 causes a deviation from M2 macrophage and regulatory T cells (Treg) to M1 macrophage and mast cells into VAT compared to WT mice fed HFD. …"

TSC1 regulates naïve CD8⁺ T cell survival to IL-7 or IL-15 in a rapamycin-insensitive manner. حسب Lianjun Zhang (181973)

"…(<b>A</b>) Significantly decreased live cell number of Tsc1 KO naïve CD8⁺T cells than WT naïve CD8⁺T cells in the presence of IL-15 or IL-7 for 24 hours. …"

DataSheet_1_Mucosal Vaccination Primes NK Cell-Dependent Development of CD8+ T Cells Against Pulmonary Brucella Infection.pdf حسب Ella Bhagyaraj (588347)

"…Their activation status was augmented noted by the increased NKp46 and granzyme B, but decreased NKG2A expression. Further analysis demonstrated that both lung caspase-1⁺ inflammatory monocytes and monocyte-derived macrophages secrete chemokines and cytokines responsible for NK cell recruitment and activation. …"