Reproductive Toxicity and Teratogenicity of Fluorene-9-bisphenol on Chinese Medaka (Oryzias sinensis): A Study from Laboratory to Field by Xiaolin Fan (1605136)

“…Toxico-transcriptome analyses showed that estrogen-responsive genes were significantly suppressed by BHPF, indicating that antagonist properties of BHPF on estrogen receptors might be causes for the decreased fecundity. Field investigations (Beijing) demonstrated that BHPF was detectable in 60% surface waters, with a mean concentration of 10.49 ± 6.33 ng/L, by gas chromatography–mass spectrometry, and similar effects in wild Chinese medaka were also observed, some of which the parameters were found to be obviously correlated with the BHPF levels in corresponding waters.…”

Reproductive Toxicity and Teratogenicity of Fluorene-9-bisphenol on Chinese Medaka (Oryzias sinensis): A Study from Laboratory to Field by Xiaolin Fan (1605136)

“…Toxico-transcriptome analyses showed that estrogen-responsive genes were significantly suppressed by BHPF, indicating that antagonist properties of BHPF on estrogen receptors might be causes for the decreased fecundity. Field investigations (Beijing) demonstrated that BHPF was detectable in 60% surface waters, with a mean concentration of 10.49 ± 6.33 ng/L, by gas chromatography–mass spectrometry, and similar effects in wild Chinese medaka were also observed, some of which the parameters were found to be obviously correlated with the BHPF levels in corresponding waters.…”

NR4A1 expression does not decrease after inhibition of p38, JNK and Src pathways. by Glenda Eger (636934)

DNA damage induces a pan-nuclear decrease in GFP-lamin A mobility. by Robert Mahen (409641)

RAC1 inhibition results in a decrease in oxidative phosphorylation. by Shruthi Sriramkumar (12705564)

Decrease in GABA_A immunoreactivity in APP mice. by Ksenia V. Kastanenka (3692380)

Oxidation of glycans results in a decreased production of IL-4 and IL-10 and an increase of IFNγ by parasite specific splenocytes. by Ernesto Rodríguez (840670)

IL-1β induced a decrease in TER values. by Tadayoshi Konno (3350282)

CRH induces a decrease in macrophage ABCA1 expression. by Wonkyoung Cho (760305)

LLO induces a decrease in Mre11 protein levels. by Ascel Samba-Louaka (361232)

Loss of MeOPN results in a decrease in serum resistance. by Lieke B. van Alphen (132099)

Identification of proteins that presented a significant decrease in their expression content. by Rubens D. M. Magalhães (395962)

BMP signal inactivation leads to a decrease of pouch progenitors. by Linwei Li (5705310)

SLE T cells display more genes with increased rather than decreased expression. by Sean J. Bradley (823158)

Learning corresponds with a decrease in intermediate-speed exploratory behaviors. by Caleb Kemere (452950)

PI3K-C2α knockdown decreases autophagy and maturation of endocytic vesicles by Nathan M. Merrill (4437367)

“…We find a significant decrease in autophagy following siRNA-mediated <i>PIK3C2A</i> (encoding the Class 2 PI3K, PI3K-C2α) knockdown. …”

HSC activation results in a preferential decrease in retinyl esters. by Nicole Testerink (169448)

Palmitate causes a decrease in mitochondrial oxygen consumption in cardiomyocytes. by Leroy C. Joseph (845300)

Predicting Vulnerabilities of North American Shorebirds to Climate Change by Hector Galbraith (636637)

“…The model is based on anticipated changes in breeding, migration, and wintering habitat, degree of dependence on ecological synchronicities, migration distance, and degree of specialization on breeding, migration, or wintering habitat. We evaluated 49 species, and for 3 species we evaluated 2 distinct populations each, and found that 47 (90%) taxa are predicted to experience an increase in risk of extinction. …”

Wnt5a expressing tumors demonstrate a decrease in markers of the basal tumor subtype. by Stephanie L. Easter (662168)