Showing 881 - 900 results of 1,773 for search '(( 10 ((((ng decrease) OR (a decrease))) OR (mean decrease)) ) OR ( 2 we decrease ))', query time: 0.16s Refine Results
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    Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

    Published 2019
    “…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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  5. 885

    EFFECT OF ENDOPLASMIC RETICULUM STRESS MEDIATED BY HYPERGLYCEMIA ON BARRIER FUNCTION IN RETINAL CELLS by Saif, Atiya Ramadan

    Published 2016
    “…Methodology: In the present study, utilizing the HRMEC, we evaluated the effect of high glucose (30mM) on several ER stress signaling pathway genes (HSPA5, EIF2K3, and XBP1) at the mRNA expression level; the inflammatory cytokines (NFkB) at the mRNA level; the adhesion molecules (ICAM-1 and P-selectin) by flow cytometry. …”
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    Enhancing the production of biogas through anaerobic co-digestion of agricultural waste and chemical pre-treatments by Almomani F.

    Published 2020
    “…The results revealed that the highest cumulative methane production (CMP) of 297.99 NL/kgVS can be generated by co-digestion of ASWs and CD at a ratio of 60:40. Further improvement was achieved via alkalinity treatment with 1.0 g of NaHCO3/gVS leading to decrease in lignin, cellulose, and hemicellulose contents of feedstock by 3.5%, 10.5% and 15.9%, respectively, converting them to soluble fractions and improving the CMP by 11.2–29.7% based on substrate quality. …”
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  18. 898

    Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function by Da'as, Sahar I.

    Published 2024
    “…Furthermore, circular dichroism spectroscopy experiments using recombinant CaM proteins reveals a decreased structural stability of the four mutants compared to the wild-type CaM protein in the presence of Ca2+. …”
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