Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

5-HT inhibits <i>P</i>. <i>berghei</i> infection in mosquitoes. by Li Gao (131516)

“…(J) Oocyst numbers in control (Ctrl, <i>n</i> = 62) and mosquitoes orally supplemented with 10 nM (<i>n</i> = 43), 100 nM (<i>n</i> = 47) and 1000 nM (<i>n</i> = 64) 5-HT. …”

Top k-NN clusters of metabolites decreased at 4 hours. by Zarazuela Zolkipli-Cunningham (5234186)

Top k-NN cluster of metabolites decreased at 30 minutes. by Zarazuela Zolkipli-Cunningham (5234186)

Decrease in circulating iNKT cell activation during regadenoson (RA) infusion into patients with COVID-19. by Joseph Rabin (7399436)

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Inhibiting translation in 5-HT neurons does not recapitulate a <i>Minute</i> phenotype. by Lisa Patricia Deliu (13570709)

Ethanol intoxication combined with burn injury decreases NFAT, Tbx21, Jun and Fos expressions in T cells. by Xiaoling Li (129705)

5-HT₇Dro knock-down decreases frequency of courtship behaviors. by Jaime Becnel (218896)

“…When compared with the parental lines 5-HT₇-Gal4 (Gal4) and UAS-sym-5-HT₇-dsRNA (UAS), the frequency of licking, curling and copulation attempts was significantly decreased. …”

Effect of 5-HTR blockade on reaction time in the work/delay task. by Yukiko Hori (299784)

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Effect of 5-HTR blockade on error pattern in the reward-size task. by Yukiko Hori (299784)

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Effect of 5-HTR blockade on reaction time in the reward-size task. by Yukiko Hori (299784)

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Effect of 5-HTR blockade on error pattern in the work/delay task. by Yukiko Hori (299784)

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Effect of 5-HTR blockade on reaction time in the work/delay task. by Yukiko Hori (299784)

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Numbers of supporting cells are unaffected in morphants, while numbers of hair cells decrease in morphants. by Fei Liu (21082)

IL-13 levels are decreased in β-Catenin knock-down-cells compared to β-Catenin-competent cells. by Sandra Michaela Frei (481531)

Stimulation of Caco-2 cells with IFN-γ decreases claudin-4 expression. by Manigandan Lejeune (458492)

Serotonin deficiency alters the protein abundance and localization of basolateral (CaSR and ORAI1) and apical (PMCA2) calcium transporters in the mammary epithelial cells on d10 of... by Jimena Laporta (383836)

MR blockade by anti-MR antibodies decreases the phagocytic and fungicidal abilities and NO production of A/J and B10.A macrophages. by Claudia Feriotti (286149)

Inducing proteotoxic stress in 5-HT neurons does not recapitulate a <i>Minute</i> phenotype. by Lisa Patricia Deliu (13570709)