Showing 21 - 40 results of 148,166 for search '(( 10 ((((nm decrease) OR (we decrease))) OR (a decrease)) ) OR ( 50 mg decrease ))', query time: 0.99s Refine Results
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    Trial profile. by Chanel Avenant (409756)

    Published 2024
    Subjects:
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    Synthesis and Biological Evaluation of MEK/mTOR Multifunctional Inhibitors as Novel Anticancer Agents by Marcian E. Van Dort (21374093)

    Published 2025
    “…Additionally, compound LP-65 demonstrated significant modulation of MEK and mTOR signaling activity in human glioma cells (D54) and human melanoma cells (A375), with a corresponding decrease in cellular proliferation and migration. Treatment of mice with LP-65 (40 mg/kg) having a myeloproliferative neoplasm, myelofibrosis, revealed down modulation of in vivo signaling pathways and therapeutic efficacy.…”
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