cAMP and PKA/AKAP1 decrease mobility and promote mitochondrial translocation of Drp1. by Ronald A. Merrill (224222)

Decrease of neuronal FKBP4/FKBP52 modulates perinuclear lysosomal positioning and MAPT/Tau behavior during MAPT/Tau-induced proteotoxic stress by Béatrice Chambraud (3371201)

“…</p> <p><b>Abbreviations:</b> AD: Alzheimer disease; AKT/protein kinase B: AKT serine/threonine kinase; ALP: Autophagy-lysosomal pathway; ATG: autophagy-related; BafA₁: bafilomycin A₁; CQ: chloroquine; CTSD: cathepsin D; DIV: days in vitro; DRG: dorsal root ganglion neurons; Dox: doxycycline; DNAJC5: DnaJ heat shock protein family (Hsp40) member C5; EL: empty lentiviral vectors; ENO2/NSE: enolase 2, gamma neuronal; FKBP4/FKBP52: FKBP prolyl isomerase 4; FTLD-Tau: frontotemporal lobar degeneration with Tau pathology; GFP: green fluorescent protein; LAMP1: lysosomal associated membrane protein 1; LDH: lactate dehydrogenase; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MAPT/Tau: microtubule associated protein tau; MTT: tetrazolium salt; NFTs: neurofibrillary tangles; RPE-1: retinal pigment epithelial cells; shRNA: small-hairpin ribonucleic acid; SQSTM1/p62: sequestosome 1; SD: standard deviation; SEM: standard error of the mean; SH-SY5Y: human neuroblastoma cells; Sh1 or Sh2: Lentiviral shRNA vectors inducing FKBP4 decrease; SH-52GFP: MAPT/Tau-inducible SH-SY5Y cell line constitutively expressing FKBP4-GFP; TUBB3/βIII tubulin: tubulin beta 3 class III; UPS: ubiquitin-proteasome system</p>…”

The AngII-induced decrease in AdipoR1 expression involves ERK1/2 activation and ROS production. by Li Li (14993)

Expression of Egln3 decreases tumor aggression, increases survival and normalizes glioma vascular architecture. by Vicki A. Sciorra (312082)

Reducing Dscam1 diversity decreases adult lifespan in an exon-specific manner, Related to Fig 3. by Haiyang Dong (4783608)

FLCN-deficiency leads to decreased Rho activity in sub-confluent cells and delays in wound closure. by Doug A. Medvetz (300145)

“…<b>B)</b> Rho activity was measured using a Rhotekin binding assay at 70% confluence. The FLCN-null UOK257 cells had a 2.5-fold decrease in active Rho levels (Rho GTP) compared to the FLCN re-expressing UOK257-2 cells (n = 3, p<0.05). …”

Decreased type I IFN response in B cells carrying the MS-protective class I alleles. by Christian Lundtoft (4068679)

Tempol and L-NAME help prevent the decrease in F_max. by Travis L. Dutka (321984)

Decrease in the HS4C3-binding epitope inhibits differentiation and apoptosis. by Kazumi Hirano (144477)

The large decrease in R but small decrease of O₂ across the night. by Matthew H. Long (387725)

“…Figure C and D show a 5 to 15% decrease in the O₂ concentration across the night which cannot explain the decrease in respiration. …”

SOD and catalase attenuate morphine-induced decrease of podcoyte expression of SD molecules. by Xiqian Lan (219539)

Microgravity induced decrease in adherent mES cells at early exposure hours. by Yulan Wang (50197)

Pathways of macrophages and neutrophils were decreased in Ad26.COV2.S vaccinated compared to sham unvaccinated hamsters. by Malika Aid (7303874)

“…<b>(B)</b> Heatmaps of the normalized expression of the leading genes contributing to the enrichment of proinflammatory macrophages increased by SARS-CoV-2 in sham animals (in green) and decreased in Ad26 vaccinated hamsters (in pink and blue) at 4 dpi. …”

Increased accumulation of mutant huntingtin aggregates and decreased mobility of autophagosomes in the axon of AP-4 ε KO hippocampal neurons. by Raffaella De Pace (5147120)

Table_1_Decreased synaptic vesicle glycoprotein 2A binding in a rodent model of familial Alzheimer's disease detected by [18F]SDM-16.DOCX by Chao Zheng (728465)

“…In this study, we tested [¹⁸F]SDM-16, a novel metabolically stable SV2A PET imaging probe, in the transgenic APPswe/PS1dE9 (APP/PS1) mouse model of AD and age-matched wild-type (WT) mice at 12 months of age.…”

Decrease of Rab28 expression attenuated activation of NF-κB in ECs. by Jun Jiang (149215)

Variability and correlations decrease during task states in human fMRI data. by Takuya Ito (57473)

“…<p>Figures for the replication cohort are in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007983#pcbi.1007983.s004" target="_blank">S4 Fig</a>. …”

Cell nuclear volume decreases under increasing osmotic pressure. by Adele Khavari (7378082)

CDK9 activity and cyclin T1 expression decrease as neutrophils age in culture. by Keqing Wang (334664)

The role of the ER stress sensor PERK in ox-LDL-induced NO decrease in HCMECs. by Dan Hong (731836)