Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice by Ayman, Alzu'bi

“…These findings were found to be correlated with increased level of oxidative stress, neuroinflammation, and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (BDNF), which plays an essential role in modulating synaptic plasticity integral for promoting learning and memory in the hippocampus. Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”
Get full text
Get full text
Get full text

Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor. by Padmanabhan, Regina

“…Precisely, several questions regarding the right combination of drugs, drug modality, and effective dose recommendations pertaining to the use of ICB-based therapy for HER2+ patients remain unanswered. In this study, we use a mathematical modeling-based approach to quantify the growth inhibition of HER2+ breast cancer (BC) cell colonies (ZR75) when treated with anti-HER2; trastuzumab (TZ) and anti-PD-1/PD-L1 (BMS-202) agents. …”
Get full text
Get full text

Towards the higher solubility and thermal stability of poly(aniline-co-m-bromoaniline) by WawareU.S.

“…In the current study, we have described the synthesis and the physical properties of poly(aniline-co-m-bromoaniline) conducting copolymers. …”
Get full text
Get full text

Kappa-Distributed Electrons in Solar Outflows: Beam-Plasma Instabilities and Radio Emissions by Lazar, M.

“…Electrostatic (ES) wave instabilities are assumed to be at the origin of radio emissions from interplanetary shocks, and solar coronal sources are most likely induced by electron beams, more energetic but less dense than electron strahls in the solar wind. In this paper, we present the results of a new dispersion and stability analysis for electron populations with Kappa velocity distributions, as often indicated by in situ observations. …”
Get full text
Get full text
Get full text

Oxygen passivation as effective technique for tailoring the nature of band gap of silicon nanowires by Hassan, Walid M.I.

“…Surprisingly, extensive oxidation dramatically decreases the silicon nanowire band gap down to 0.26 eV. …”
Get full text
Get full text
Get full text

Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells. by Al-Jaber, Hend

“…To investigate insulin signaling's influence in vitro by IRinducing factors, we assessed phospho-protein levels. Our results reveal a significant p-Akt induction with chronic high insulin (10%) and acute TNFα (12%) treatment under hypoxia (both P<0.05). …”
Get full text
Get full text

Microbiota-derived acetate activates intestinal innate immunity via the Tip60 histone acetyltransferase complex by Bat-Erdene, Jugder

“…In these cells, the IMD pathway co-regulates expression of antimicrobial and enteroendocrine peptides including tachykinin, a repressor of intestinal lipid synthesis. To determine whether acetate acts on a cell surface pattern recognition receptor or an intracellular target, we asked whether acetate import was essential for IMD signaling. …”
Get full text
Get full text
Get full text

Locations of Temporary Distribution Facilities for Emergency Response Planning by Pradhananga, Rojee

“…Therefore, in this paper, we propose a network flow model for emergency response planning which provides location and allocation plans of temporary distribution facilities for short distribution periods in the planning horizon. …”
Get full text
Get full text

Burden and trend of diet-related non-communicable diseases in Australia and comparison with 34 OECD countries, 1990-2015: findings from the Global Burden of Disease Study 2015. by Melaku, Yohannes Adama

“…Diet is a major determining factor for many non-communicable chronic diseases (NCDs). …”
Get full text
Get full text

Run Rules-Based EWMA Charts for Efficient Monitoring of Profile Parameters by Yeganeh, Ali

“…The proposed EWMAR chart with run rules exhibits a much better performance in detecting small and decreasing shifts than the other competing charts. …”
Get full text
Get full text

SARS-CoV-2 infection triggers more potent antibody-dependent cellular cytotoxicity (ADCC) responses than mRNA-, vector-, and inactivated virus-based COVID-19 vaccines by Zedan, Hadeel T.

Get full text
Get full text
Get full text

Plasma volume variations in response to high intensity interval training in obese women: The influential role of menopausal status and age by Jabbour, Georges

“…MethodsWe enrolled fifty-nine obese women (perimenopausal and postmenopausal), aged approximately 56.6 years in a six-week HIIT program. …”
Get full text
Get full text
Get full text

Omega-3 fatty acid-rich fish oil supplementation prevents rosiglitazone-induced osteopenia in aging mice by Cugno, Chiara

“…Rosiglitazone is an effective insulin-sensitizer, however, associated with bone loss mainly due to increased bone resorption, and bone marrow adiposity, and decreased bone formation. We investigated the effect of the co-administration of fish oil (FO) rich in omega-3 fatty acids (FAs) on rosiglitazone (RSG)-induced bone loss in aging C57BL/6 mice and the mechanisms underlying potential preventive effect. …”
Get full text
Get full text

Fecal Carriage and Molecular Characterization of Carbapenemase-Producing Enterobacterales in the Pediatric Population in Qatar by Pérez-López, Andrés

Get full text
Get full text
Get full text

Spatial-temporal pattern of cultivated land productivity based on net primary productivity and analysis of influencing factors in the Songhua River basin by Yang, Shiliang

“…However,evaluating the impact of the intensity and direction of CLP in large-scale areas is a difficulty and a gap. In this study, we used net primary productivity (NPP) to calculate the productivity of cultivated land and reveal its spatial differentiation. …”
Get full text
Get full text

Epibenthic communities from offshore platforms in the Arabian Gulf are structured by platform age and depth by Felipe, Torquato

“…Oil and gas platforms act as artificial habitats for a myriad of marine organisms. In this study, we used opportunistic remotely operated vehicle (ROV) data to describe fouling assemblages through the characterization of functional groups in the Al Shaheen oil field, situated in Qatari waters. …”
Get full text
Get full text
Get full text

Epibenthic communities from offshore platforms in the Arabian Gulf are structured by platform age and depth by Felipe, Torquato

“…Oil and gas platforms act as artificial habitats for a myriad of marine organisms. In this study, we used opportunistic remotely operated vehicle (ROV) data to describe fouling assemblages through the characterization of functional groups in the Al Shaheen oil field, situated in Qatari waters. …”
Get full text
Get full text
Get full text

Location privacy preservation in secure crowdsourcing-based cooperative spectrum sensing by Zina, Chkirbene

“…The existing solutions present a high level of complexity which decreases the performance of the systems. …”
Get full text
Get full text

Who needs RDD? Combining directory listings with cell phone exchanges for an alternative telephone sampling frame by Guterbock, Thomas

“…The portion of the telephone universe that is excluded in the EWP+cell design is getting smaller all the time, therefore its bias relative to the RDD+cell design is decreasing over time. Overall, the EWP+cell design seems to be a useful alternative.…”
Get full text
Get full text

In-depth Analysis of Pedestrian Safety in the State of Qatar by Kharbeche, Mohamed

“…Pedestrian safety is of a serious concern as it includes children and the aged population. …”
Get full text
Get full text