A computational method to characterize the missense mutations in the catalytic domain of GAA protein causing Pompe disease. by Thirumal Kumar, D

“…These data are expected to serve as a platform for drug design against Pompe disease and will serve as an ultimate tool for variant classification and interpretations.…”
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Enhanced Filtration Characteristics and Reduced Bacterial Attachment for Reverse Osmosis Membranes Modified by a Facile Method by Nnadiekwe, Chidera C.

“…The original membrane showed a water contact angle of ∼90−100° that was significantly decreased after silane coating: 63° for 3-APS and ∼52° for 6-AHAS. …”
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Climate change will seriously impact bird species dwelling above the treeline: A prospective study for the Italian Alps by Ferrarini, Alessandro

“…The study area extends over 20,700 km2, ranging over 550 km in longitude and 320 km in latitude. We then investigated how much the expected treeline rise will induce a) shrinking and shifting of the elevation range and b) loss in suitable habitat for the flagship species rock ptarmigan, an alpine bird species dwelling above the treeline and, similarly to many other alpine species, highly vulnerable to treeline rise. …”
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Morphology, Nucleation, and Isothermal Crystallization Kinetics of Poly(ε-caprolactone) Mixed with a Polycarbonate/MWCNTs Masterbatch by Gumede, Thandi P.

“…Isothermal crystallization experiments performed by DSC showed an increase in the overall crystallization kinetics of PCL with increases in MWCNTs as a result of their nucleating effect. Nevertheless, the crystallinity degree of the nanocomposite containing 4 wt % MWCNTs decreased by about 15% in comparison to neat PCL. …”
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7-O-methylpunctatin, a novel homoisoflavonoid, inhibits phenotypic switch of human arteriolar smooth muscle cells by Fardoun M.

“…In this study, we show that MP decreased FBS-induced cell proliferation, migration, invasion, and adhesion. …”
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Docosahexaenoic Acid, a Key Compound for Enhancing Sensitization to Drug in Doxorubicin-Resistant MCF-7 Cell Line. by Crovella, Sergio

“…Other observed effects included a decrease in the multi-drug resistance (MDR) carrier P-glycoprotein (P-gp) and TG2, a tumor survival factor. …”
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Environment Degradation and Economic Growth in the Qatar Economy: Evidence from a Markov Switching Equilibrium Correction Model by Charfeddine, Lanouar

“…From the economic perspective, this means that initially economic growth increases environment degradation and then declines it after a threshold point of income per capita. …”
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Elucidating the role of interacting residues of the MSH2-MSH6 complex in DNA repair mechanism: A computational approach. by Thirumal Kumar, D

“…From the simulation studies, we observed higher deviation, lower protein compactness, and a decrease in the number of intramolecular hydrogen bonds in the mutant W764C MSH2-MSH6 protein complex. …”
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Psychiatric inpatients' views of their mental health, and their experience of social change, during the pandemic: A report from Qatar by Badanapurkar, Ashishkumar

“…Mental health nurses have a pivotal role including identifying early warning signs of relapse of mental disorders, delivering talking treatments and providing practical advice and COVID-19-related education. …”
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Topiramate monotherapy for weight reduction in patients with type 2 diabetes mellitus: A systematic review and meta-analysis by Paravattil, Bridget

“…Results: Of the 284 studies identified, 5 studies fulfilled the inclusion criteria. Topiramate decreased weight by a mean difference of 3.4 kg (95% CI, -3.79 to -3.04) compared to placebo. …”
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Association between Lebanese Mediterranean Diet and Frailty in Community-Dwelling Lebanese Older Adults—A Preliminary Study by Daou, Tracy

“…The results showed that a higher LMD adherence was associated with a significantly decreased frailty prevalence (OR = 0.123, 95% CI: 0.022–0.676, p = 0.016 when categorical and OR = 0.773, 95% CI 0.608–0.983, p = 0.036). …”
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Adaptation of a Mice Doppler Echocardiography Platform to Measure Cardiac Flow Velocities for Embryonic Chicken and Adult Zebrafish. by Benslimane, Fatiha M

“…However, these are originally built for mice studies and they need to be tested and evaluated for smaller experimental models. We recently adapted a mice Doppler echocardiography system to measure cardiac flow velocities for adult zebrafish and embryonic chicken. …”
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A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase by Thirumal Kumar, D

“…MDS run showed that the C145A mutant demonstrated higher structural deviation, decreased compactness, and the binding patterns. …”
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Non-steroidal anti-inflammatory drugs and bone healing in animal models-a systematic review and meta-analysis by Al-Waeli, Haider

“…Methods: We performed a systematic review and meta-analysis of animal studies to estimate the effect of NSAID administration after bone fracture on healing outcomes. …”
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Comparison of seed germination and recovery responses of a salt marsh Halophyte halopeplis perfoliata to osmotic and ionic treatments by Rasool S.G.

“…In order to partition salinity effects, we studied seed germination and recovery responses of a coastal salt marsh halophyte Halopeplis perfoliata to different isotonic treatments (?…”
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A new method for broad-scale modeling and projection of plant assemblages under climatic, biotic, and environmental cofiltering. by Ferrarini, Alessandro

“…There is increasing interest in broad-scale analysis, modeling, and prediction of the distribution and composition of plant species assemblages under climatic, environmental, and biotic filtering, particularly for conservation purposes. We devised a method (broad-scale analysis & modeling of plant assemblages under climatic-biotic-environmental co-filtering, BAM-PACC) for reliably predicting the impact of climate change on arbitrarily large assemblages of plant communities, while also considering competing biotic and abiotic factors. …”
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Association between metabolically healthy obesity and metastasis in lung cancer patients – a systematic review and meta-analysis by Malki, Ahmed

“…A statistically significant decreased risk of LC (pooled RR = 0.72, 95% CI: 0.68 to 0.77) was also observed in the obese individuals. …”
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Chemical characterization and anti-hemolytic anemia potentials of tin nanoparticles synthesized by a green approach for bioremediation applications by Ahmeda, A.

“…In this study, tin nanoparticles were synthesized and characterized in aqueous medium using Ziziphora clinopodioides Lam leaf aqueous extract as the reducing and stabilizing agent. We also assessed the antihemolytic anemia potential of tin nanoparticles (SnNPs) in an animal model of hemolytic anemia. …”
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Investigating the structural impacts of a novel missense variant identified with whole exome sequencing in an Egyptian patient with propionic acidemia by Ibrahim, Ali Zaki

“…Propionic Acidemia (PA) is an inborn error of metabolism caused by variants in the or genes, leading to mitochondrial accumulation of propionyl-CoA and its by-products. Here, we report a 2 year-old Egyptian boy with PA who was born to consanguineous parents. …”
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Adiposity indicators exhibit depot- and sex-specific associations with multimorbidity onset: A cohort study of the UK Biobank by Ma, Lu

“…Central obesity, as defined by waist circumference, contributed to a 23.2% increased risk of incident multimorbidity. …”
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