PRMT5-PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells حسب Banasavadi-Siddegowda, Y K

"…Our results uncover a very significant role for PRMT5 in GBMNS self-renewal capacity and proliferation. …"
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Ubiquitin-Related Modifier 1 (URM-1) Modulates Cx43 in Breast Cancer Cell Lines. حسب El-Hajjar, Layal

"…In particular, the PTM of connexin 43 (Cx43), a tumor suppressor protein, regulates its turnover and activity. …"
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Fluorinated Benzofuran and Dihydrobenzofuran as Anti-Inflammatory and Potential Anticancer Agents حسب Ayoub, Abeer J.

"…Targeting inflammation in cancer associated with chronic inflammation is a promising therapy. In the present study, we investigated the anti-inflammatory effects of fluorinated benzofuran and dihydrobenzofuran derivatives in macrophages and in the air pouch model of inflammation, as well as their anticancer effects in the human colorectal adenocarcinoma cell line HCT116. …"
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Gas Driven Fracture during Gas Production using HeleShaw Cell حسب Al-Raoush, Riyadh

"…Methane hydrate is considered a potential energy source, with worldwide reserves on the order of 500-10,000 Gt of carbon. …"
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Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice حسب Ayman, Alzu'bi

"…These findings were found to be correlated with increased level of oxidative stress, neuroinflammation, and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (BDNF), which plays an essential role in modulating synaptic plasticity integral for promoting learning and memory in the hippocampus. Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …"
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Conceptual Based Hidden Data Analytics and Reduction Method for System Interface Enhancement Through Handheld devices حسب Babi, Syrinne Adnan

"…In addition, by using online consecutive reductions on search results, we adopted a method of displaying results in order of decreasing relevance. …"
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Screening the growth inhibition mechanism of sulfate reducing bacteria by chitosan/lignosulfonate nanocomposite (CS@LS) in seawater media حسب Kashif, Rasool

"…Herein, we have developed a biodegradable chitosan/lignosulfonate nanocomposite (CS@LS) as an efficient green biocide for the inhibition of SRBs biofilms. …"
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Synthesis and properties of HA/ZnO/CNT nanocomposite حسب Ding M.

"…The goal of this study was to examine the tribomechanical properties of hydroxyapatite (HA)/ZnO and HA/ZnO/CNT composite ceramics (carbon nanotubes; with different ratios 0.5 wt%, 1.0 wt%, and 1.5 wt%). The composites were synthesized using the hydrothermal method in an autoclave. …"
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VacoNet: Variable and connected architecture for data center networks حسب Chkirbene, Zina

"…Motivated by these challenges, we propose a new data center architecture called VacoNet that combines the advantages of existing architectures while avoiding their limitations. …"
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Dynamic workload patterns prediction for proactive auto-scaling of web applications حسب Iqbal W.

"…This may lead to inappropriate resource provisioning decisions. In this paper, we address these challenges by proposing a framework for prediction of dynamic workload patterns as follows. …"
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Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria حسب Al-Sadeq, Duaa W.

"…In this study, we present the clinical and biochemical characterization of two novel CBS missense mutations that do not respond to pyridoxine treatment, namely c.689T > A (L230Q) and 215A > T (K72I), identified in a Chinese patient. …"
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Synthesis and characterization of stir casted Cu-ZrO2-Graphite hybrid metal matrix composites for thermal management structures حسب Mittal, Prateek

"…ZrO2 and Graphite reinforcements were added (0.5–0.5, 1.0–1.0, 1.5–1.5 and 2.0–2.0 wt %) in the four composite samples prepared via stir casting. …"
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Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs حسب Salloum-Asfar, Salam

"…Moreover, miRNA, piRNA, and snoRNAs expression profiles in iPSCs and original fibroblasts were assessed to identify the potential role of ncRNAs in enhancing iPSC generation, pluripotency, and differentiation. Decreased levels of let-7a-5p showed an increase of SP8 as described previously. …"
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Hydrogel Sensors for the Agricultural Applications حسب Ali, Ruba

"…We chose to use hydrogel in soil, for their high efficiency in absorbing water. …"
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Thermally assisted efficient electrochemical lithium extraction from simulated seawater حسب Yanxi, Yu

"…Based on these understandings, we demonstrated that a thermally assisted electrochemical lithium extraction process could achieve rapid (36.8 mg g-1 day-1) and selective (51.79% purity) lithium extraction from simulated seawater with an ultrahigh Na+/Li+ molar ratio of 20,000. …"
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Effect of biochars produced from solid organic municipal waste on soil quality parameters حسب Randolph, P.

"…Select municipal organic wastes (newspaper, cardboard, woodchips and landscaping residues) individually or in a 25% blend of all four waste streams were used as feedstocks of biochars. …"
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Salinity inhibits seed germination of perennial halophytes Limonium stocksii and Suaeda fruticosa by reducing water uptake and ascorbate dependent antioxidant system حسب Hameed, Abdul

"…Germination and hydration of the seeds of both species decreased with increases in NaCl concentration. CAT and GPX activities were higher while APX, AsA and GSH decreased in salt stressed seeds compared to water-imbibed seeds. …"
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Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice حسب Ayman, Alzu'bi

"…These findings were found to be correlated with increased level of oxidative stress, neuroinflammation, and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (BDNF), which plays an essential role in modulating synaptic plasticity integral for promoting learning and memory in the hippocampus. Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …"
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Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor. حسب Padmanabhan, Regina

"…Precisely, several questions regarding the right combination of drugs, drug modality, and effective dose recommendations pertaining to the use of ICB-based therapy for HER2+ patients remain unanswered. In this study, we use a mathematical modeling-based approach to quantify the growth inhibition of HER2+ breast cancer (BC) cell colonies (ZR75) when treated with anti-HER2; trastuzumab (TZ) and anti-PD-1/PD-L1 (BMS-202) agents. …"
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Towards the higher solubility and thermal stability of poly(aniline-co-m-bromoaniline) حسب WawareU.S.

"…In the current study, we have described the synthesis and the physical properties of poly(aniline-co-m-bromoaniline) conducting copolymers. …"
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