Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein inter... by Thirumal Kumar, D.

“…From the analysis, we observed the highest deviation with lowest compactness and a decrease in the intramolecular h-bonds in the BRCA1-BARD1 protein complex with the V11G mutation compared to the native complex or the complexes with other mutations. 2022 Elsevier Inc.…”
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Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. by P, Sneha

“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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Pharmacoeconomic evaluation of voriconazole vs. liposomal amphotericin B in empiric treatment of invasive fungal infections in Turkey by Turner, Stuart J.

“…Univariate sensitivity analysis highlighted that increasing the duration of voriconazole by >1.2 days or decreasing LAmB by >1.0 days changes the result. Monte Carlo Simulation resulted in 69.4% of simulations favouring voriconazole per patient treated.Conclusion: There is a strong likelihood that voriconazole is economically more favourable than LAmB in the empiric treatment of IFI in Turkey.…”
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Molecular dynamics of CH4/CO2 on calcite for enhancing gas recovery by Carchini, Giuliano

“…These results highlight how the CO2 geometry of adsorption is well defined and characterized by strong interaction, while methane adsorption is quite loose and depicts a very dynamic picture. Focusing on the effect of pressure, RDF peaks intensities increase, although this effect is limited to the 1-5 MPa range. …”
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Smoking cessation counseling in Qatar: Community pharmacists' attitudes, role perceptions and practices by El Hajj, Maguy Saffouh

“…Main outcome measures: Qatar community pharmacists' smoking cessation practices, their attitudes toward tobacco use, smoking cessation and smoking cessation counseling and their perceived barriers for smoking cessation counseling. Results: Over 5 months, we collected 127 surveys (40 % response rate). …”
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Origanum Syriacum Inhibits Proliferation, Migration, Invasion and Induces Differentiation of Human Aortic Smooth Muscle Cells by AlDisi, Sara

“…Cardiovascular diseases (CVDs) are still the number one cause of morbidity and mortality both in Qatar and worldwide. A major risk factor of CVDs is atherosclerosis, the hardening of blood vessels caused by decreased diameter and formation of plaque. …”
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Understanding the progress and challenges in the fields of thermo-catalysis and electro-catalysis for the CO2 conversion to fuels by Yadav, V. S. K.

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Fabrication of Selective Sensors for Hg2+ Traces in Water Using Graphene Decorated with Metal Nanoclusters by Ayesh, Ahmad I.

“…The system consists of three main chambers (source, mass filter, and deposition chambers) that were pumped initially to a base pressure of 10-8 mbar using two turbo pumps. …”
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Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries by Pathadka, Swathi

“…Consumption of ketoconazole slowly declined, with 5.04% annual decrease, probably due to labelling changes in 2013 to reflect hepatotoxicity concerns. …”
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Pd nanocrystals encapsulated in MOF-derived Ni/N-doped hollow carbon nanosheets for efficient thermal CO oxidation: unveiling the effect of porosity by Ipadeola, Adewale K.

“…This is evidenced in the great ability of Pd/Ni-MOF-HNC to utterly oxidize CO at a lower complete conversion temperature (T100) of 114.5 °C compared with Pd/Ni-MOF-NC (153.8 °C) and Pd/C (201.5 °C) under atmospheric pressure. …”
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Montmorency tart cherry supplementation does not impact sleep, body composition, cellular health, or blood pressure in healthy adults by Hillman, Angela R.

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National trends of outcomes in transcatheter aortic valve replacement (TAVR) through transapical versus endovascular approach: From the National Inpatient Sample (NIS). by Abugroun, Ashraf

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STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS by AL-SADEQ, DUAA WALID

“…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …”
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Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics by Nomikos, Michail

“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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Exchange counterion in polycationic hydrogels: Tunability of hydrophobicity, water state, and floating capability for a floating ph device by Danko, Martin

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Environment Degradation and Economic Growth in the Qatar Economy: Evidence from a Markov Switching Equilibrium Correction Model by Charfeddine, Lanouar

“…From the economic perspective, this means that initially economic growth increases environment degradation and then declines it after a threshold point of income per capita. …”
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Rapid decline in family size in Oman: Untangling the puzzles and paradoxes by Islam, M Mazharul

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Development of CuAg/Cu2O nanoparticles on carbon nitride surface for methanol oxidation and selective conversion of carbon dioxide into formate by Nazir, Roshan

“…Herein we report a catalyst consisting of CuAg/Cu2O nanoparticles (NPs), synthesized on the two-dimensional carbon nitride (CN) surface via galvanic exchange route for electrocatalytic methanol oxidation and carbon dioxide reduction. …”
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Mixed Solid Municipal Waste-Based Biochar for Soil Fertility and Greenhouse Gas Mitigation by Bansode, Rishipal

“…Municipal solid waste management is one of the major challenges facing Qatar with more than 2.5 million tons of municipal solid waste each year, a very high waste generation rate in a country with small land mass. …”
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Nonlinear stochastic modeling for optimal dispatch of distributed energy resources in active distribution grids including reactive power by Mehrjerdi, Hasan

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