Treatment of pFTY720 in vivo and in vitro reduces MOG reactive splenocyte-induced demyelination isolated from MOG-immunised mice. by Adam J. Pritchard (575041)

“…Bar graph illustrates relative MBP immunoreactivity (i.e. co-localization of MBP and neurofilament) in cerebellar slices compared to no treatment (100% as control) expressed as averages +/− SEM (20 slices per treatment group). There was a significant decrease of MBP staining in slices co-cultured with vehicle treated MOG reactive splenocytes compared to control slices (*p<0.05), which was reduced by pFTY720 treatment; One-way ANOVA and Newman-Keuls post-hoc test. …”

Transcription of Genes Involved in Sulfolipid and Polyacyltrehalose Biosynthesis of <em>Mycobacterium tuberculosis</em> in Experimental Latent Tuberculosis Infection by Jimmy E. Rodríguez (385705)

“…A striking decrease in the transcription of <i>mmpL8</i> and <i>mmpL10</i> transporter genes and increased transcription of the <i>pks</i> (polyketidesynthase) genes involved in SL and DAT biosynthesis were detected in both the NRP2 stage and the murine model of chronic infection. …”

Schematic summarizing the data shown in Fig 8. by Ana Rita Amândio (558664)

“…<p>In a wild type situation and at a body level anterior to <i>Hoxc11</i> expression (from example in the upper lumbar region such as L3 or L4), <i>Hoxc10</i> is active whereas the whole posterior part of the <i>HoxC</i> cluster is repressed (top left). …”

Involvement of γ-secretase-dependently transcribed genes in Wnt pathways. by Alexandra I. Magold (259441)

“…<p>Several key players of the canonical Wnt pathway (green panel) were reported by our microarray to increase (red quadrangles) or decrease (blue quadrangles) in transcript levels under conditions of enhanced γ-secretase activity compared to inhibited activity. β-Catenin is a central node connecting Wnt–Frizzled–Dishevelled to a downstream effect influencing the cell cycle (see also <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0006952#pone-0006952-g003" target="_blank">Fig. 4</a> and interactions of encoded proteins). …”

Robustness to variations in timescale. by Satohiro Tajima (251177)

“…(B) Optimal <i>embeddedness</i> in the all electrode pairs decreased by 0.21 times with the longer unit delay (p<10⁻⁵, sign test, paired sample across all electrode pairs). …”

DataSheet1_Unraveling Structural Phase Transformation by Simultaneously Determining the Lattice Constants and Mismatch Angle in VO2/Al2O3 Epitaxial Thin Films.docx by Yichao Liu (3982652)

“…The lattice constants a, b, and c were approximately 5.723, 4.521, and 5.393 Å, respectively, at room temperature, and the mismatch angle was approximately 122.02°. …”

E-cigarettes (2.4% nicotine) plus HFD inactivates AMPK. by Kamrul M. Hasan (9450158)

“…GAPDH in the immunoblot is shown as a loading control. P<0.05. Values are given as means ± SE of 5 mice per group. * P<0.05.…”

Short term kinetic of anti-F1 IgM in <i>R. rattus</i> after inoculation with <i>Y. pestis</i>. by Voahangy Andrianaivoarimanana (264615)

“…Rats are from two villages Ambohimasina and Maromanana. (median; bar: 10% and 90% percentiles) A/Time course of the median OD ratio of each group: OD ratio peaked at Day 13 and decreased rapidly after B/Median of OD ratio obtained at Day13 and Day 25 for the two villages according to the dose inoculated. …”

Erratum: Reduction of Arteriosclerotic Nanoplaque Formation and Size by n-3 Fatty Acids in Patients after Valvular Defect Operation by Koppe C. (4271533)

“…Additionally, the quotient oxLDL/LDL was lowered by 6.8 ± 2.1% (p < 0.0166), the MDA concentration remained unchanged and the lipoprotein(a) concentration decreased by 15.8 ± 5.6% (p < 0.0469) in the patients’ blood. …”

SPATIO-TEMPORAL ANALYSIS OF LANDSCAPE PATTERNS IN THE CATOLÉ WATERSHED, NORTHERN MINAS GERAIS1 by Rodrigo Nogueira Martins (5960138)

“…From the LULC maps, classes related to the natural landscape (dense, sparse, and riparian vegetation) were grouped into forest patches, which was then ordered by size: very small (< 5 ha); small (5 - 10 ha); medium (10 - 100 ha); large (100 ha); and a general class (no distinction of patch size). …”

Dietary patterns and colorectal cancer by Tayyem, Reema F.

“…In the Healthy Pattern group we found a 10.54% variation in food intake, while the intake variation was 11.64% in the Western Pattern. …”
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Optical “Blinking” Triggered by Collisions of Single Supramolecular Assemblies of Amphiphilic Molecules with Interfaces of Liquid Crystals by Michael Tsuei (1315353)

“…For 100 μM of DLPC, we measured vesicles with a diameter of 940 ± 290 nm to generate 47 ± 9 blinks min^–1 mm^–2, revealing that the fraction of vesicle collisions resulting in fusion with the LC interface is ∼10^–3. …”

siRNA-mediated AKAP12 and AKAP220 knockdown significantly impaired endothelial barrier function. by Mariya Y. Radeva (625707)

“…AKAP12 and AKAP220 depletion lead to a significant decrease in TER compared to monolayers transfected with n.t. siRNA. …”

DataSheet1_Access to Cleaning Services Alters Fish Physiology Under Parasite Infection and Ocean Acidification.pdf by José Ricardo Paula (6031580)

“…Moreover, after an acclimation period of 10 days to high CO₂ (∼1,000 µatm CO₂), the fish showed a decrease in factorial aerobic scope, being the lowest in fish without the access to cleaners. …”

Promotion of Low-Humidity Proton Conduction by Controlling Hydrophilicity in Layered Metal–Organic Frameworks by Masaaki Sadakiyo (1536262)

“…The most hydrophilic sample, <b>Me-FeCr</b>, adsorbed a large number of water molecules and showed a high proton conductivity of ∼10^–4 S cm^–1, even at a low humidity of 65% relative humidity (RH), at ambient temperature. …”

FRLFE suppresses iNOS induction by the IL-1β signaling pathway. by Ryota Yamanishi (547533)

“…The bold arrows indicate the decreases caused by FRLFE in this study. The proinflammatory cytokine IL-1β binds to its receptor (type I IL-1 receptor, IL1R1) to activate NF-κB through the IκB kinase (IKK) signaling pathway <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0093818#pone.0093818-Takimoto1" target="_blank">[23]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0093818#pone.0093818-Lawrence1" target="_blank">[25]</a>. …”

FFD – main effect, original fibrosis burden. by Åshild Telle (22794721)

“…<p>(A) Main effect plots for each parameter and each metric, across all simulation combinations (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013265#pcbi.1013265.t003" target="_blank">Table 3</a>) and all three patients. …”

Identification of amino acids is robust against systematic error. by Samuel G. Rodriques (6523655)

“…However, this decreased concentration necessitates a longer runtime. …”

Determinants of Sensitivity to DZNep Induced Apoptosis in Multiple Myeloma Cells by Zhigang Xie (203103)

“…Western-blot analysis indicated ALOX5 was highly expressed only in sensitive cell line H929 and greatly decreased upon DZNep treatment. …”

DataSheet1_New mechanistic insights into the RAS-SIN1 interaction at the membrane.pdf by Silke Pudewell (13914792)