Mammalian METTL10 is an EF1A1 KMT. by Tadahiro Shimazu (619411)

Subjects:

Normal TLR4 and MD2 expression and decreased IL10 secretion and A20 expression by <i>cpdm</i> BMDC. by Zhe Wang (41178)

Activator A10 increases and inhibitor G8 decreases the rate of PMA-induced PKCε-EGFP translocation in HeLa cells. by Milla Summanen (325769)

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EBP is involved in the kE-induced GM₃ levels decrease. by Anthony Rusciani (359756)

Dose- and time-dependent effect of IFN-γ and TNF-α on benzamil-sensitive <i>I</i>_sc and TEER in HBECs. by Anusree Sasidharan (19226521)

MAP-2 decrease follows the early PSA-NCAM reduction induced by glutamate exposure. by María Fernanda Podestá (639243)

“…MAP-2: microtubule-associated protein 2; PSA-NCAM: polysialylated form of NCAM. Scale bars: 50 µm.</p>…”

Development of Selective and Soluble Mitochondrial Complex 1 Inhibitors Derived from Papaverine for Radiosensitization of Cancer by Ben J. Haines (22458462)

Subjects:

Development of Selective and Soluble Mitochondrial Complex 1 Inhibitors Derived from Papaverine for Radiosensitization of Cancer by Ben J. Haines (22458462)

Subjects:

Insulin ICV injection (14 mU) decreases olfactory detection in fasted rats. by Pascaline Aimé (293920)

“…Before the conditioning, during the last day of habituation (Hab.), both tubes were filled with pure water, and during the first day of aversion acquisition (Av.), both tubes were filled with ISO 10⁻⁵. A repeated measure ANOVA revealed a significant effect of the aversive conditioning (p<0.0001). …”

Endotoxin tolerance is associated with decreased TNFα and increased IL-10, S100A8 and S100A9 mRNA expressions. by Mathieu Fontaine (582183)

Inhibition of COX isoforms on murine norovirus (MNV) infection leads to decreased MNV replication. by Mia Madel Alfajaro (572993)

EGFR/ERK signaling activity decreases throughout LEC elimination with endocytic activity dependency. by Kevin Yuswan (19845885)

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(C)</b> Total cholesterol quantification (with fluorometric assay kit) in NIH3T3 cells depleted with sterols for 2 h or exposed to different CO₂ levels for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, **<i>P</i> < 0.01, nonsignificant (ns), two-sided Student’s <i>t</i> test). <b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …”

Treatment with TDF decreased cell viability and induced morphological changes in hepatic stellate cells. by Sung Won Lee (222509)

Nasal mucociliary clearance was decreased in <i>Ttll1</i>^−/− mice. by Toshiyuki Iwata (419270)

“…Treatment with tosufloxacin did not decrease cough (bars indicate median values, n = 4 per group; NS = not significant). …”

KCl treatment increases Elk1 SUMOylation and decreases katanin-p60 expression. by Ece Selçuk (436963)

Global Land Use Change Impacts on Soil Nitrogen Availability and Environmental Losses by Jing Wang (6206297)

“…In contrast, reversing managed to natural ecosystems significantly increased NNM by 20% (9.7, 25.4%) and decreased NN by 89% (−125, −46%), indicating increasing N availability while decreasing potential N loss. …”

VSL#3 decreases epithelial paracellular permeability in a TNF-dependent manner on ilea from pre-inflamed SAMP mice. by Daniele Corridoni (148198)

Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant by Ittipat Meewan (7455041)

“…Hepatitis C virus (HCV) is a human pathogen with high morbidity. The HCV NS3/4A protease is essential for viral replication and is one of the top three drug targets. …”

AAV-mediated Atp6v1c1 knockdown decreased TRAP positive cells and Atp6v1c1 expression in the periodontitis lesion area. by Sheng Li (107261)