Modifying pregnenolone to decrease its lipophilicity results in decreased cellular uptake. by Jeffrey M. McManus (7512926)

Substance P decreases PRL immunoreactivity in human epidermis. by Ewan A. Langan (405804)

A blue-shifted fluorescence donor increases fAP amplitude but exhibits a decreased SNR. A. by Ann E. Fink (312543)

Intestinal CD5⁺ B cells produce greater level of IL-10 than CD5^- B cells in response to Toll-like receptor ligands. by Yoshiyuki Mishima (842248)

ECRG4 regulates neutrophils migration to chemoattractants. by Katie D. Pool (20141584)

Effects of subchronic exposure of silver nanoparticles on intestinal microbiota and gut-associated immune responses in the ileum of Sprague-Dawley rats by Katherine Williams (44356)

“…The results indicate that AgNP prompted size- and dose-dependent changes to ileal-mucosal microbial populations, as well as, intestinal gene expression and induced an apparent shift in the gut microbiota toward greater proportions of Gram-negative bacteria. DNA-based analyses revealed that exposure to 10 nm AgNP and low-dose silver acetate caused a decrease in populations of <i>Firmicutes</i> phyla, along with a decrease in the <i>Lactobacillus</i> genus. …”

Electronic cigarette power affects count concentration and particle size distribution of vaping aerosol by Evan L. Floyd (3924086)

Radical Quantum Yields from Formaldehyde Photolysis in the 30 400–32 890 cm^–1 (304–329 nm) Spectral Region: Detection of Radical Photoproducts Using Pulsed Laser Photoly... by Cheryl Tatum Ernest (2067766)

A3F translocations on ssDNA are distinct from A3G, but not due to intersegmental transfer. by Anjuman Ara (540372)

“…A3F processivity was not observable until the distance between cytosines was greater than 14 nt apart (denoted with x), but then increased until 100 nt (filled squares). …”

CORT triggered a slow-onset increase in GluN2A/GluN2B ratio. by Yiu Chung Tse (340737)

“…<p>(<b>A</b>) Plots of NMDAR-EPSC amplitude from control and CORT-treated slices against time show decreased EPSC amplitude after sequential application of Ro (1 µM; for 30 min) and a mixture of Ro and a subunit non-selective NMDAR antagonist APV (50 µM; for 10 min). …”

A Single Molecule Investigation of the Photostability of Quantum Dots by Eva Arnspang Christensen (138327)

Data Sheet 1_A systematic review of the effects of nanoplastics on fish.pdf by Asok K. Dasmahapatra (2275549)

Methotrexate enhances BIO-mediated inhibition of phosphorylation at GSK3-specific residues (Ser33/37/Thr41) on β-catenin. by Richard A. Klinghoffer (260120)

“…Exposure of cells to suboptimal BIO (312 nM) plus methotrexate (312 nM) led to a greater decrease in phosphorylated β-catenin than exposure to the same dose of BIO alone (compare lanes 4 and 5). …”

(A and B) HEK293 cells were transfected with htt (1–208 aa) containing 23Q or 130Q and scFv-EM48 ( scFv) by Chuan-En Wang (48485)

The effector functions of CHK-152 contribute to protection <i>in vivo</i>. by Pankaj Pal (404355)

“…Comparison of binding of ch-CHK-152 and ch-CHK-152 N297Q to FcγR (CD16A, 500 nM; CD32A, 100 nM; and CD64, 100 nM) or C1q (50 nM), as measured by surface plasmon resonance. …”

The proteasome inhibitor Bortezomib inhibits not only FANC signaling, but also HR, Alt-EJ, and end resection. by Sean M. Howard (687174)

“…U2OS cells were treated with Bortezomib (100 nM, 4 hr before IR treatment) or vehicle (DMSO) as well as with an individual FANCA siRNA (siFANCA-3) or non-targeting siRNA (siCTRL). …”

Adhesion of Als5 to collagen type IV involves recognition of carbohydrate residues on collagen type IV but is not solely determined by it. by Mohammad Faiz Ahmad (172608)

“…Flow chart representing the various steps of the assay is shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0035305#pone.0035305.s005" target="_blank">Figure S5</a>.…”

Hormone addition results in chromatin changes at individual GR-regulated genes. by Chuong D. Pham (111374)

“…We calculate that a nucleosome/bare ratio of 1.0 corresponds to ∼50% nucleosome occupancy, while a value of 2.1 corresponds to 100% occupancy (e.g. a nucleosome covering a given location on all gene copies). …”

Aptamer array features are uniform, discrete, and highly reproducible. by Nicholas O. Fischer (94124)

“…The eight identical subarrays were individually yet simultaneously interrogated with decreasing concentrations of IgE (100 nM to 0.1 nM). …”

Microarray analysis of endoxifen concentration-dependent changes in gene expression in the presence of estrogen and physiologically relevant levels tamoxifen and its metabolites. by John R. Hawse (227611)

“…<p> (<b>A</b>) Venn diagram of genes whose expression levels were significantly altered by 1.5 fold or greater in MCF7 cells treated with 10 nM estrogen (E₂), 300 nM tamoxifen (TAM), 7 nM 4-hydroxy-tamoxifen (4HT) and 700 nM N-desmethyl-tamoxifen (NDT), plus indicated concentrations of endoxifen, relative to cells treated with all compounds minus endoxifen for 24 hours. …”