AKT inhibition decreases neuroblast populations. by Maria R. Aburto (186884)

“…<p>(<b>A</b>) SOX2 expression upon PI3K-AKT inhibition. …”

FTY720 treatment decreased phosphorylation of AKT, ERK, and c-myc. by Laura L. Stafman (6577184)

“…<p>(A) Immunoblotting for the activated form of AKT–phospho-AKT (Ser473)–and total AKT revealed a decrease in phospho-AKT with no accompanying change in total AKT, indicating a decrease in AKT signaling with FTY720 treatment. …”

Bone mass and formation are decreased in Akt1-/- mice. by Naohiro Kawamura (33999)

Diabetes and TPEN treatment decreased the expression of Nrf2 that was associated with decreased Akt and GSK-3β phosphorylation and nuclear accumulation of Fyn. by Chi Zhang (9857)

Afatinib decreases MAPK and AKT activation after MET knockdown. by Karolin Ebert (7434713)

GSK3 inhibition results in a decrease of p-β-Catenin. by Germán Cuesto (701284)

“…Only the treatment with 2 and 10 μM of AR-A014418 decreased p-β-Catenin levels. …”

Knockdown of ErbB2 decreases phosphorylation of Akt and CNC migration. by Ketan Mathavan (4634704)

DIO induces a decrease in pAkt(Thr308) in the striatum and substantia nigra. by Nicole Speed (203357)

Akt2 ablation resulted in a substantial decrease in cell proliferation and cell survival. by Stacey A. Santi (231259)

“…(<b>B</b>) Among three Akt isoforms, Akt2 ablation caused the greatest decrease in the colony forming ability. …”

Riluzole decreases AKT phosphorylation and activity. A. by Walid Abushahba (303111)

Subjects:

A2M* decreases growth of tumour xenografts in mice. by Susanne Kurz (759116)

Variable importance plot (mean decrease accuracy and mean decrease Gini). by Fernando Martinez-Taboada (8655132)

Thimerosal decreases the expression of survivin via the PI3K/Akt pathway. by Wen-Xue Li (189757)

Knockdown of S6K2 decreased Mcl-1. by Alakananda Basu (3842152)

VEGF sequestration decreases PI3K-Akt and MAPK-ERK pathway signaling. by Minna M. Wieck (849372)

“…<p>Western blot data for (A) PI3K, (B) phosphorylated and total Akt, and (C) phosphorylated and total ERK1/2 demonstrate decreased activation of these signaling pathways in mutants. …”

Akt dysfunction is associated with decreases in myosin, actin and muscle fiber cross-sectional area. by Miaozong Wu (371373)

Acute cocaine administration decreased pAkt-Thr308 in the caudate putamen of mice. by Jonathan S. Miller (519857)

“…<p>Levels of pAkt-Thr308 and pAkt-Ser473 were measured by Western blot analysis in mouse caudate putamen, nucleus accumbens and frontal cortex obtained 30 minutes following a single injection of cocaine (20 mg/kg). (1A) Cocaine significantly decreased pAkt-Thr308 (***p<0.001) and (1B) had no effect on pAkt-Ser473 in the caudate putamen. (1C&D) Levels of pAkt-Thr308 and pAkt-Ser473 were not changed in the nucleus accumbens or (1E&F) frontal cortex after cocaine administration. …”

Osr1 heterozygous mice experienced decreased bile acid synthesis in the liver. by Ernest C. Lynch (12769954)

“…(D) Osr1 heterozygous male mice had significantly decreased expression of <i>Cyp7a1</i>, <i>Cyp27a1</i>, <i>Ehhadh</i>, <i>Cyp4a10</i> and <i>Cyp4a14</i> compared to WT male mice. …”

2-ME decreases blood pressure in Sprague Dawley rats. by Weiyu Chen (2216251)

Decrease in cell migration and adhesion of MCF10A cells after knockdown of <i>MYO1C</i>. by Kittichate Visuttijai (3204519)

“…A dose-dependent decrease in relative cell index response to MYO1C depletion was observed reaching to a significant value with concentrations of 5 and 10 nM of <i>MYO1C</i>-siRNA at 48 hours post-transfection compared to control cells (mock transfection). …”