Image_1_Multi-omics analysis identifies IgG2b class-switching with ALCAM-CD6 co-stimulation in joint-draining lymph nodes during advanced inflammatory-erosive arthritis.tif by H. Mark Kenney (10320665)

“…Integration of single-cell and spatial transcriptomics revealed the increased IgG2b⁺ plasma cells localized in MARCO⁺ peri-follicular medullary sinuses. A concomitant decreased Fth1 expression (Early 2.5 ± 0.74 vs Advanced 1.0 ± 0.50 counts, p<0.001) within Advanced PLN sinuses was associated with accumulation of iron-laden Prussian blue positive macrophages in lymph nodes and synovium of Advanced TNF-Tg mice, and further validated in RA clinical samples. …”

Image_2_Multi-omics analysis identifies IgG2b class-switching with ALCAM-CD6 co-stimulation in joint-draining lymph nodes during advanced inflammatory-erosive arthritis.tif by H. Mark Kenney (10320665)

“…Integration of single-cell and spatial transcriptomics revealed the increased IgG2b⁺ plasma cells localized in MARCO⁺ peri-follicular medullary sinuses. A concomitant decreased Fth1 expression (Early 2.5 ± 0.74 vs Advanced 1.0 ± 0.50 counts, p<0.001) within Advanced PLN sinuses was associated with accumulation of iron-laden Prussian blue positive macrophages in lymph nodes and synovium of Advanced TNF-Tg mice, and further validated in RA clinical samples. …”

Image_3_Multi-omics analysis identifies IgG2b class-switching with ALCAM-CD6 co-stimulation in joint-draining lymph nodes during advanced inflammatory-erosive arthritis.tif by H. Mark Kenney (10320665)

“…Integration of single-cell and spatial transcriptomics revealed the increased IgG2b⁺ plasma cells localized in MARCO⁺ peri-follicular medullary sinuses. A concomitant decreased Fth1 expression (Early 2.5 ± 0.74 vs Advanced 1.0 ± 0.50 counts, p<0.001) within Advanced PLN sinuses was associated with accumulation of iron-laden Prussian blue positive macrophages in lymph nodes and synovium of Advanced TNF-Tg mice, and further validated in RA clinical samples. …”

Table_1_Decadal Variations of Wood Decay Hazard and El Niño Southern Oscillation Phases in Iran.XLSX by Jalil Helali (11822426)

Wild inside: Urban wild boar select natural, not anthropogenic food resources by Milena Stillfried (3201564)

“…We categorized the WB into five stomach content categories but found no significant difference in the frequency of those categories between urban and rural WB. …”

Data_Sheet_1_Oral Vaccination Reduces the Effects of Lawsonia intracellularis Challenge on the Swine Small and Large Intestine Microbiome.pdf by Fernando L. Leite (5690174)

“…Vaccination altered both small and large intestine microbiome community structure and led to a significant 3.03 log₁₀ reduction in the amount of L. intracellularis shed by the challenged pigs. …”

Data_Sheet_1_Contractility of Induced Pluripotent Stem Cell-Cardiomyocytes With an MYH6 Head Domain Variant Associated With Hypoplastic Left Heart Syndrome.pdf by Min-Su Kim (183958)

“…Functional assessments performed between D20-D23 revealed that MYH6-R443P variant CMs contracted more slowly (40 ± 2 vs. 47 ± 2 contractions/min, P < 0.05), shortened less (5.6 ± 0.5 vs. 8.1 ± 0.7% of cell length, P < 0.05), and exhibited slower shortening rates (19.9 ± 1.7 vs. 28.1 ± 2.5 μm/s, P < 0.05) and relaxation rates (11.0 ± 0.9 vs. 19.7 ± 2.0 μm/s, P < 0.05). …”

MiR-185 and 342 inhibition of SREBP mRNA and protein and expression patterns of miR-185 and 342 in prostate cancer cells. by Xiangyan Li (443886)

“…The relative mRNA expression (fold) was assigned as 1.0 in non-transfected cells. Data were normalized to 18S rRNA and represent the mean ± SD of three independent duplicate experiments. **, <i>P</i> < 0.005 significant differences from NC. …”

Effects of RUNX3 on the abilities of growth and metastasis in vitro. by Lijie He (224405)

“…<p>a. After infection, the expression of RUNX3 in 786-O-Ctrl and 786-O-RUNX3 was evaluated by Western blot. …”

Effect of seliciclib anf flavopiridol combined treatment on hMMCLs viability, cell cycle distribution and cyclin expression. by Liat Josefsberg Ben-Yehoshua (324970)

“…(C) Combined treatment with seliciclib and flavopiridol increases subG1 and decreases G2/M fractions in hMMCLs. Data are represented as mean±standard deviation. …”

Evaluation of copromicroscopy and serology to measure the exposure to <i>Ascaris</i> infections across age groups and to assess the impact of 3 years of biannual mass drug administ... by Daniel Dana (717754)

Fasudil Protects the Heart against Ischemia-Reperfusion Injury by Attenuating Endoplasmic Reticulum Stress and Modulating SERCA Activity: The Differential Role for PI3K/Akt and JAK... by Yapeng Li (124282)

“…Administration of fasudil at 10 mg/Kg significantly attenuated ROCK activation during reperfusion and resulted in an improved SERCA activity which was closely associated with decreases in temporal activation of ER stress and IS changes. …”

Cited4 is related to cardiogenic induction and maintenance of proliferation capacity of embryonic stem cell-derived cardiomyocytes during <i>in vitro</i> cardiogenesis by Junichiro Miake (4373017)

“…Therefore, in the present study, we investigated the expression patterns and functional roles of the <i>Cited4</i> gene during <i>in vitro</i> cardiogenesis. …”

Image_2_Effect of β-Hydroxybutyrate on Autophagy Dynamics During Severe Hypoglycemia and the Hypoglycemic Coma.TIF by Carmen Torres-Esquivel (9408707)

“…Here, we aimed to investigate autophagy dynamics in the brain of rats subjected to severe hypoglycemia (SH) without glucose infusion (GI), severe hypoglycemia followed by GI (SH + GI), and a brief period of hypoglycemic coma followed by GI (Coma). …”

Image_1_Effect of β-Hydroxybutyrate on Autophagy Dynamics During Severe Hypoglycemia and the Hypoglycemic Coma.TIF by Carmen Torres-Esquivel (9408707)

“…Here, we aimed to investigate autophagy dynamics in the brain of rats subjected to severe hypoglycemia (SH) without glucose infusion (GI), severe hypoglycemia followed by GI (SH + GI), and a brief period of hypoglycemic coma followed by GI (Coma). …”

Apolipoprotein B48, the Structural Component of Chylomicrons, Is Sufficient to Antagonize <i>Staphylococcus aureus </i>Quorum-Sensing by Bradley O. Elmore (282347)

“…Therefore, we hypothesized that apoB48 would be sufficient to antagonize <i>S</i>. …”

ARG1 and ARG2 are metabolically active. by Philippe O. Gannon (243970)

“…Post-transfection (24 hours), cells were plated in charcoal-stripped serum supplemented media for 72 hours and then stimulated for 72 hours with 10 nM R1881. A) siRNA inhibition of ARG1 and ARG2 expression was evaluated by Western Blot. …”

<i>In</i><i>vitro</i> characterization of SGSCs. by Sabine Nagel (476531)

Data_Sheet_1_Laser-Induced Apoptosis of Corticothalamic Neurons in Layer VI of Auditory Cortex Impact on Cortical Frequency Processing.docx by Katja Saldeitis (11111214)

“…Specifically, we found a decreased gain of best-frequency input in thalamocortical (TC)-recipient input layers that correlated with the relative lesion of layer VI neurons, but not layer V neurons. …”

Early Onset Pre-Eclampsia Is Associated with Altered DNA Methylation of Cortisol-Signalling and Steroidogenic Genes in the Placenta by Kirsten Hogg (283182)

“…Significant hypomethylation was observed in pre-eclampsia but not nIUGR placentae for steroidogenic genes, including <i>CYP11A1</i> (exon1; EOPET; −9.66%; <i>P</i><0.00001, and LOPET; −5.77%; <i>P</i><0.001), 3β-hydroxy-delta-5-steroid dehydrogenase type 1 (<i>HSD3B1</i> exon 2; EOPET; −12.49%; <i>P</i><0.00001, and LOPET; −6.88%; <i>P</i><0.001), TEA domain family member 3 (<i>TEAD3</i> intron 1; EOPET; −12.56%; <i>P</i><0.00001) and <i>CYP19</i> (placental-specific exon 1.1 promoter; EOPET; −10.62%, <i>P</i><0.0001). …”