Extracellular nutrient dependences of <i>in vitro</i> cancer cell lines. by Iñigo Apaolaza (6628892)

“…The significance of the difference in LDLR and SLC5A3 CERES scores in the auxotrophic groups against the corresponding prototrophic group was assessed via a one-tailed Wilcoxon test.…”

Steiner forest prediction of pathways activated by KSHV infection. by Zoi E. Sychev (3813169)

“…<p><b>(A.)</b> List of the top KEGG pathways predicted to be altered by KSHV infection of endothelial cells from Steiner forest network and KEGG pathways database analysis (complete list in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1006256#ppat.1006256.s008" target="_blank">S1 Table</a>). …”

Identification of an SMC-specific Ryr3 regulated by SRF. by Moon Young Lee (749843)

“…Seven transmembrane domains 1–7 and a pore region (magenta) are shown. MR1-5 (blue), SPRY1-3 (dark green), FKBP1A (orange), CALM (purple), and a residue E (black) that is required for Ca²⁺ binding (Ca²⁺) are also indicated. …”

Table 9_Cryptosporidium parvum infection alters the intestinal mucosa transcriptome in neonatal calves: impacts on epithelial barriers and transcellular transport systems.docx by Arash Veshkini (13286325)

“…Differentially expressed genes (DEG) between the infected and CTRL groups were assessed using DESeq2 at a false discovery rate < 0.05 and used for gene ontology (GO) and pathway enrichment analysis in Cytoscape (v3.9.1).…”

Data_Sheet_1_Deciphering Pro-angiogenic Transcription Factor Profiles in Hypoxic Human Endothelial Cells by Combined Bioinformatics and in vitro Modeling.pdf by Arne Schmidt (12886205)

“…Screening the promoter and upstream regulatory elements of these genes identified two TFs, KLF5 and SP1, both with a potential binding site within these regions of selected target genes. …”

Table_1_Csf2 Attenuated Sepsis-Induced Acute Kidney Injury by Promoting Alternative Macrophage Transition.XLSX by Yiming Li (40290)

“…In addition, the switch from the proinflammatory M1 phenotype to the M2 phenotype occurred via the p-Stat5 pathway, which was activated by Csf2. Importantly, we found that intraperitoneal injection of a Csf2-neutralizing antibody after CLP aggravated kidney injury and suppressed tubular proliferation, subsequently decreasing survival. …”

Squirrel Abundance by Angela Joseph (631109)

“…The size of the squirrels were visually observed based on how big they were and were scaled from 1-5, where 1 was a small squirrel and 5 was a large squirrel.…”

Table_1_Deciphering Pro-angiogenic Transcription Factor Profiles in Hypoxic Human Endothelial Cells by Combined Bioinformatics and in vitro Modeling.xlsx by Arne Schmidt (12886205)

“…Screening the promoter and upstream regulatory elements of these genes identified two TFs, KLF5 and SP1, both with a potential binding site within these regions of selected target genes. …”

Table 1_Increasing vulnerability of an endemic Mediterranean-climate conifer to changing climate and fire regime.docx by Frank W. Davis (8218293)

“…Ensembles of MAXENT and General Boosted Models were produced for a 2.1 million ha model domain encompassing BDF’s 672,000 ha range for the period 1981–2010, and were projected to 2040–2069 and 2070–2099 using three climate models (warmer-wetter, warmer, and hotter-drier) under a high emission scenario (IPCC 5th Assessment, RCP 8.5). …”

Inhibitory effects of 6AN on myocardial function in isolated rat hearts. by Dhwajbahadur K. Rawat (304142)

“…A: perfusion of the heart with 6AN decreased coronary perfusion pressure (CPP). …”

Action potentials for the epicardial formulations of six human ventricular models. by Mohamed M. Elshrif (507362)

“…Because of electrotonic coupling effects, all of the model APs lose amplitude in tissue compared to single cells, with the PB model decreasing the most (23.7%) followed by the GPB model (17.6%), the TP model (12.9%), the OVVR model (12.4%), the IMW model (10.5%), and the BCF model (4.0%).…”

Inhibin expression network at atresia. by Christopher J. Martyniuk (243374)

“…The abbreviations are provided in the supplementary abbreviation list (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0059093#pone.0059093.s005" target="_blank">File S5</a>).…”

Model fits to data from the <i>in vitro</i> killing assay. by Thea Hogan (631181)

“…<p>We applied the model of CTL-target conjugation and killing to data from the <i>in vitro</i> killing assay, using T and B cell targets pulsed at four different doses of peptide (decreasing, top to bottom). Free target cells are in blue (T cell) or orange (B cells); green (T cell) and red (B cell) lines are targets in conjugates with F5 CTL that have not degranulated and stain LAMP1a⁻; black lines are LAMP1a⁺ conjugates, which are CTL conjugated to targets following release of lytic granules.…”

Electrical activity simultaneously recorded from two SCN sub-populations. by Floor van Oosterhout (119430)

“…Bin size is 0.5 s, and lines in color represent the averaged firing frequency per 10 s. …”

EHEC-Hly-containing OMVs are internalized via dynamin-dependent endocytosis. by Martina Bielaszewska (79970)

“…Nuclei were stained with DRAQ5 (blue). Pictures were taken using a laser-scanning microscope (LSM 510 META microscope equipped with a Plan-Apochromat 63x/1.4 oil immersion objective). …”

Chemokine TA concentrations in infants treated with iNO compared to placebo-treated controls. by Mandy Laube (729938)

“…<b>A:</b> IP-10 TA levels were significantly decreased on PD2 in iNO-treated infants (⋆⋆, p<0.01) and increased with advancing postnatal age from PD2 to PD14 in both groups (###, p<0.001). …”

Bioinformatics analysis of the gene pathways that were enriched in the N.g MDP–treated osteocytes and verification <i>in vitro</i>. by Zheng-Rong Gao (12488388)

“…The size of the nodes and the intensity of the color indicate the gene number and mean P value. (C) qRT-PCR showed decreased expression of clock mRNA, n = 3. …”

In Vitro Effect of ASM-024 on Intracellular Calcium Rise of Stimulated Human Bronchial Smooth Muscle Cells. by Evelyne Israël-Assayag (709530)

“…<p>Pre-incubation with ASM-024 for 10 minutes decreases [Ca2+]i rise in cells stimulated with 10–5 M histamine (A) or methacholine (B). …”

DataSheet_1_Pharmacodynamic and Metabolomics Studies on the Effect of Kouyanqing Granule in the Treatment of Phenol-Induced Oral Ulcer Worsened by Sleep Deprivation.docx by Pan Chen (385477)

“…KYQG significantly reduced the levels of 5-HT and GABA in serum, and only decreased the 5-HT level in brain tissue after phenol injury followed by sleep deprivation. …”

Role of the tumor cell microenvironment in efficacy of the treatment. by Yangjin Kim (191134)

“…As the diffusion coefficient <i>D</i>_<i>L</i> on the left half plane is decreased (from (D) to (A)), i.e., brain tissue is getting tougher, the efficacy of bringing those invasive cancerous cells back to the resection site is decreased. …”