Lithium treatment inhibited the GSK-3 pathway in hippocampal neurons after TMT treatment. by Juhwan Kim (441263)

“…<p>At 12 DIV, hippocampal neurons were pre-treated with lithium (5 mM) 1 h before TMT treatment (5 µM). (A) Representative immunoblots for phospho-GSK-3α (Ser²¹), total GSK-3α (∼51 kDa), phospho-GSK-3β (Ser⁹), total GSK-3β (∼46 kDa), β-catenin (∼92 kDa) and β-actin (∼45 kDa). …”

History-Dependent Excitability discriminates between input doublets. by Fabiano Baroni (234173)

“…Dashed lines indicate the bisectrix ISI = ISI, and the lines of constant mean ISI ISI = 1 and ISI = 2, along which is plotted in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015023#pone-0015023-g003" target="_blank">Fig. 3B</a>. values have been passed through the sigmoidal function to improve visualization. …”

Influence of saliency manipulations on enumeration performance. by David Melcher (337162)

“…<p>A. Across all three conditions (shown as separate symbols and lines), percent correct enumeration decreased as a function of the number of items; F(8,5) = 37.93, p<0.001). …”

Ni-P-TiO2 Composite coatings on copper produced by sol-enhanced electroplating by Wang, Yuxin

“…The optimal mechanical properties can be achieved when the sol concentration is 12.5 mL/L. In this case, the microhardness of Ni-P-12.5 mL/L TiO2 composite coatings can reach ~710 HV while the Ni-P is ~520 HV. …”
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Shortened and disorganized growth plate in mice with disrupted BMP signaling. by Bettina Keller (231677)

“…(H) Compared to WT control, <i>Smad1^cKO/cKO</i> and <i>Smad1^cKO/cKO;Smad5^+/−</i> primary chondrocytes exhibit blunted response to rhBMP2 treatment, as revealed by decreased pSmad1,5 levels in the Western blots. α-tubulin is used as loading control.…”

Mitochondrial membrane potential in response to 12 hours of oxygen- glucose deprivation. by Jordan M. Willcox (531224)

“…Untreated astrocytes demonstrated an increase in monomer staining compared with relaxin-2, relaxin-3 and R3/I5. Control astrocytes indicate astrocytes that were not exposed to OGD and loaded with JC-1 as a control. …”

Effects of vildagliptin, metformin, and combined drugs on infarct size, Bax, and Bcl-2 expression. by Nattayaporn Apaijai (600757)

“…NDV, ^†p<0.05 vs. HFDV, n = 5/group. (D) Bcl-2 expression was decreased in HFDV, and all treatments increased Bcl-2 expression in HFD rats. …”

S-nitrosylation pattern during <i>Trypanosoma cruzi</i> trypomastigotes adhesion to extracellular matrix. by Milton Pereira (719447)

“…The Ponceau’s staining was used as a load control. Arrows indicate protein bands in which the signal intensity is decreased on the group incubated with the extracellular matrix in relation to the equivalent group incubated with growth media alone. …”

The WW3 domain of Nedd4.2 interacts with AMOTL1. by Kassiani Skouloudaki (167949)

“…Precipitation of wild type F.AMOTL1 immobilized both myc.Nedd4.2 and V5.YAP1 (left panel), while precipitation of mutant F.AMOTL1PY1/2, lacking both PPxY motifs, immobilized V5.YAP1, but only small amounts of myc.Nedd4.2 (right panel). …”

Synaptic weights and receptive field of slow-decaying (NMDA) edge-orientation classifiers. by Etay Hay (211940)

“…<p><b>A.</b> Synaptic weights from model first-order neurons onto classifier units using slow-decaying (NMDA) synapses and tuned to 20°, with presentation time window of 50 ms and noise level 5%. …”

Effects of Urtica dioica Seeds on Oxidative/ Nitrosative Stress Levels and Myeloperoxidase Activity in Muscle Ischemia/Reperfusion Injury by Meltem Gungor (14370342)

“…Saline and UD were administered via intraesophageal canula once a day for five days. At the end of five days, all the rats were exposed to muscle ischemia for 60 min followed by 60 min of reperfusion of the bilateral hindlimbs induced using a tourniquet. …”

SEAwise report on the impact of socio-economic effects of fisheries management by Isabella Bitetto (20145735)

“…In contrast, trawlers would benefit from a moderate temperature increase (RCP4.5) due to its positive effect on shrimp stocks. …”

<i>C</i>. <i>albicans</i> shows transcriptional changes specific to the presence of IECs during infection. by Jakob L. Sprague (18087148)

“…An asterisk indicates the time points with a statistically significant difference in gene expression (DESeq2 p < 0.05). The mean MRN values are given in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1012031#ppat.1012031.s011" target="_blank">S1 Table</a>.…”

MicroRNA-149 is downregulated in Alzheimer’s disease and inhibits β-amyloid accumulation and ameliorates neuronal viability through targeting BACE1 by Wenyan Du (9758108)

“…Serum miR-149 expression was downregulated in AD patients and served as a potential diagnostic biomarker. The overexpression of miR-149 in Aβ-treated SH-SY5Y cells resulted in inhibited Aβ accumulation and enhanced neuronal viability. …”

Miller chromatin spreads of rDNA from Rat1 depletion strains. by Konstantin Axt (519241)

“…In the presence of methionine, the fraction of genes with NTC decreased significantly in the empty plasmid strain over the Rat1 plasmid strain (P = 1.4×10⁻⁶), with further reduction in the Rat1_D235A strain (Rat1_D235A to empty plasmid P = 0.008; Rat1_D235A to Rat1 wild-type P = 5.1×10⁻¹³).…”

Brn3b and Brn3c expression is rapidly lost after optic nerve injury. by Francisco M. Nadal-Nicolás (298387)

“…<p><b>A-P</b>: Magnifications from SD flat mounted retinas analyzed 3 and 5 days after intraorbital nerve crush (<b>A–H</b>) and intraorbital nerve transection (<b>J–P</b>). …”

Response of hepcidin transcript levels to serum deprivation and protein kinase inhibition. by Melanie Volke (369151)

“…<p>(<b>A</b>) Serum withdrawal rapidly decreased hepcidin transcript levels in Huh7 cells. …”

Effects of age and weaning conditions on blood indicators of oxidative status in pigs by Arnaud Buchet (4045493)

“…In DC pigs, BAP was also decreased (P < 0.05) 12 days after weaning. On trial B, plasma concentrations of vitamins A and E decreased and HPO increased 5 and 19 days respectively after weaning (P < 0,001). …”

Carnosol attenuates <i>Acinetobacter baumannii</i> virulence by interfering with indole-mediated quorum sensing by Binbin Cui (194032)

Supplementary Material for: IRF4 gene expression on the trail of molecular response: looking at chronic myeloid leukemia from another perspective by Tarantini F. (13904547)