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_ decrease » _ decreased (Expand Search), _ decreases (Expand Search), _ decreasing (Expand Search)
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meter » meters (Expand Search), peter (Expand Search)
_ decrease » _ decreased (Expand Search), _ decreases (Expand Search), _ decreasing (Expand Search)
a decrease » _ decreased (Expand Search), _ decreases (Expand Search)
b decrease » _ decreased (Expand Search), _ decreases (Expand Search)
meter » meters (Expand Search), peter (Expand Search)
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Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro
Published 2016“…In conclusion, this study demonstrated that Hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis, eNOS mediated NO production increases with hyperglycemia but remarkably decreases with insulin treatment after 1 hour, 2 hours and 4 hours, insulin could counteract the hyperglycemic effect on AKT/pI3 kinase which mediates NO production and VEGF-A, decreased adhesion molecules p-selectin involved in barrier disorder of retinal endothelial cells. …”
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