video2_A Novel Alginate-Based Delivery System for the Prevention and Treatment of Pressure-Overload Induced Heart Failure.mp4 by Ambrish Kumar (558337)

Implantation of a Berlin Heart EXCOR by Monroe McKay (17019630)

Data_Sheet_2_Moso bamboo (Phyllostachys edulis (Carrière) J. Houzeau) invasion affects soil microbial communities in adjacent planted forests in the Lijiang River basin, China.PDF by Hongping Sun (6631166)

DataSheet_1_Zerumbone Modulates α2A-Adrenergic, TRPV1, and NMDA NR2B Receptors Plasticity in CCI-Induced Neuropathic Pain In Vivo and LPS-Induced SH-SY5Y Neuroblastoma In Vitro Mod... by Jasmine Siew Min Chia (8524626)

“…Involvement of specific adrenoceptors were investigated using antagonists— prazosin (α₁-adrenoceptor antagonist), idazoxan (α₂-adrenoceptor antagonist), metoprolol (β₁-adrenoceptor antagonist), ICI 118,551 (β₂-adrenoceptor antagonist), and SR 59230 A (β₃-adrenoceptor antagonist), co-administered with zerumbone (10 mg/kg). Involvement of excitatory receptors; TRPV and NMDA were conducted using antagonists capsazepine (TRPV1 antagonist) and memantine (NMDA antagonist). …”

<i>pals-17</i> mutant phenotypes are fully <i>pals-16</i>-dependent. by Vladimir Lažetić (5047592)

“…<p>(A, B) <i>pals-16</i> RNAi decreases <i>pals-5</i>p::GFP expression in <i>pals-17 pals-20</i> mutants. …”

DataSheet2_Exploring pyrrolidinyl-spirooxindole natural products as promising platforms for the synthesis of novel spirooxindoles as EGFR/CDK2 inhibitors for halting breast cancer... by Mohamed S. Nafie (9754305)

“…<p>Cancer represents a global challenge, and the pursuit of developing new cancer treatments that are potent, safe, less prone to drug resistance, and associated with fewer side effects poses a significant challenge in cancer research and drug discovery. …”

DataSheet1_Exploring pyrrolidinyl-spirooxindole natural products as promising platforms for the synthesis of novel spirooxindoles as EGFR/CDK2 inhibitors for halting breast cancer... by Mohamed S. Nafie (9754305)

“…<p>Cancer represents a global challenge, and the pursuit of developing new cancer treatments that are potent, safe, less prone to drug resistance, and associated with fewer side effects poses a significant challenge in cancer research and drug discovery. …”

Fig 4 - by Laure Bridoux (481118)

“…The highest HOX dose corresponds to 100%; HOXA2 (red) is translated at progressively decreasing levels, either alone, or co-translated with progressively increasing levels of HOXA3 (green) (e.g. 75% HOXA2; 75% HOXA2 + 25% HOXA3; 50% HOXA2; 50%HOXA2 + 50% HOXA3; 50% HOXA3 as indicated below the gel). …”

Table_1_Practical Model to Optimize the Strategy of Adjuvant Postmastectomy Radiotherapy in T1-2N1 Breast Cancer With Modern Systemic Therapy.docx by Fei-Fei Xu (538090)

“…After a median follow-up of 69 months, the 5-year rate of DFS, BCSS, and LRR in the overall cohort was 90.2%, 97.4%, and 3.6%, respectively. …”

Defective eviction of nucleosomes surrounding 5’ Gcn4 motifs in SWI/SNF and RSC mutants. by Yashpal Rawal (606804)

“…<b>(C-E)</b> Notched box plots for the 3 sets of 5’ sites defined in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010277#pgen.1010277.g002" target="_blank">Fig 2A and 2B</a> and indicated again in (B), depicting (C) H3 occupancies per base pair in the ±100 bp windows surrounding the Gcn4 motifs, (D) log₂ Gcn4 occupancies taken from <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010277#pgen.1010277.g002" target="_blank">Fig 2C</a>, and (E) log₂ Rpb3 occupancies averaged over the CDS of genes with 5’ sites. …”

Characterizing the connectivity of in vitro neuronal networks. by Christian Donner (3663007)

“…<p><b>A</b> Firing rate cumulative density function (CDF) of 600 spike-sorted units from HD-MEA recordings obtained from primary cortical cultures (top panel; n = 6 cultures; 100 units per network; recording duration: 1 h; culture age: DIV 14); and CDF of inter-spike interval coefficients of variation (ISI CV) for the same cultures (lower panel). …”

Table 1_Vitamin D3 promotes white fat beige through IL-27/P38MAPK/PGC-1α pathway.docx by Yanqiu Zhou (2172931)

“…After VD₃ intervention, TC, TG, and the number of LDs were significantly reduced in both HFD rats and 3T3-L1 cells, and serum IL-6 and MCP-1 in HFD rats were decreased. Meanwhile, there was a significant increase in mRNA and protein expression for VDR, IL-27R, P38MAPK, and PGC-1α. …”

<i>C</i>. <i>elegans</i> SNX-3 is required for formation of clathrin-independent recycling endosomal tubules. by Yangli Tian (4871416)

“…<p>(A) Confocal images provide the effect of various SNX mutant or RNAi treatment on the subplasmalemmal hTAC-GFP-containing tubular endosomes. …”

Starvation increases arousal threshold. by Elizabeth B. Brown (4582978)

“…Flies were sleep deprived for 24 hrs using either mechanical vibration or 0.5mg/mL caffeine. (K) Sleep profile. (L) Relative to control, sleep duration significantly decreases for each method of sleep deprivation (two-way ANOVA: F_1,234 = 21.58, <i>P</i><0.0001), and occurs only at night (<i>P</i><0.0001). …”

JAK/STAT signaling promotes high global translation rates in CySCs. by Ruoxu Wang (9312306)

“…Asterisks mark the hub. (C, C′) A wild-type testis showing highest OPP in CySCs adjacent to the hub and decreasing OPP levels with increasing distance from the hub. …”

The pathway of ADF7-inhibited-VLN1 is involved in osmotic-induced F-actin depolymerization and ROS accumulation. by Shuangtian Bi (5183459)

“…<p><b>(A)</b> Confocal microscopy images of epidermal cells visualized by the expression of <i>fABD2</i>::<i>GFP</i> in root apices from Col-0 seedlings under mannitol treatments (200 mM) for 0, 3, 6, and 9 h. …”

Table 5_Clinical effect of unilateral biportal minimally invasive surgery in the treatment of patients with spinal degenerative diseases based on intelligent multimodal reconstruct... by Quan Sun (175631)

“…Objective<p>To explore the effect of unilateral biportal minimally invasive surgery in the treatment of patients with spinal degenerative diseases based on intelligent multimodal reconstruction technology.</p>Methods<p>A total of 100 patients with spinal degenerative diseases treated with unilateral biportal endoscopy during 2023–2024 in Orthopedics Center of our hospital were selected as research objects. …”

Table 8_Clinical effect of unilateral biportal minimally invasive surgery in the treatment of patients with spinal degenerative diseases based on intelligent multimodal reconstruct... by Quan Sun (175631)

“…Objective<p>To explore the effect of unilateral biportal minimally invasive surgery in the treatment of patients with spinal degenerative diseases based on intelligent multimodal reconstruction technology.</p>Methods<p>A total of 100 patients with spinal degenerative diseases treated with unilateral biportal endoscopy during 2023–2024 in Orthopedics Center of our hospital were selected as research objects. …”

Table 4_Clinical effect of unilateral biportal minimally invasive surgery in the treatment of patients with spinal degenerative diseases based on intelligent multimodal reconstruct... by Quan Sun (175631)

“…Objective<p>To explore the effect of unilateral biportal minimally invasive surgery in the treatment of patients with spinal degenerative diseases based on intelligent multimodal reconstruction technology.</p>Methods<p>A total of 100 patients with spinal degenerative diseases treated with unilateral biportal endoscopy during 2023–2024 in Orthopedics Center of our hospital were selected as research objects. …”

Table 3_Clinical effect of unilateral biportal minimally invasive surgery in the treatment of patients with spinal degenerative diseases based on intelligent multimodal reconstruct... by Quan Sun (175631)

“…Objective<p>To explore the effect of unilateral biportal minimally invasive surgery in the treatment of patients with spinal degenerative diseases based on intelligent multimodal reconstruction technology.</p>Methods<p>A total of 100 patients with spinal degenerative diseases treated with unilateral biportal endoscopy during 2023–2024 in Orthopedics Center of our hospital were selected as research objects. …”