An association between decreasing incidence of invasive non-typhoidal salmonellosis and increased use of antiretroviral therapy, Gauteng Province, South Africa, 2003–2013 by Karen H. Keddy (833179)

“…</p><p>Results</p><p>From 2003–2013, the incidence of iNTS per 100,000 population per year decreased from 5.0 to 2.2 (p < .001). From 2004 to 2013, the incidence per 100,000 population of HIV viral load testing increased from 75.2 to 3,620.3 (p < .001). …”

Level of short-chain fatty acids (SCFAs) in rat feces is decreased after ceftriaxone administration (300 mg/kg, i.m., 14 days). by Yuliia Holota (7300700)

Association between dietary flavonoid and decreased eGFR/increased uACR in the US population. by Peijia Liu (3694051)

Cancellous bone microarchitecture assessed by μCT of the distal femur from 8.5–9 week old <i>Notch3</i>^{<i>em1Ecan</i>} mutant (gray bars) male mice and sex-matched litter... by Ernesto Canalis (516050)

Cortical bone microarchitecture assessed by μCT of the mid-diaphyseal femur from 8.5–9week old <i>Notch3</i>^{<i>em1Ecan</i>} mutant (gray bars) male mice and sex-matched l... by Ernesto Canalis (516050)

Evolutionary History of Atmospheric CO₂ during the Late Cenozoic from Fossilized <i>Metasequoia</i> Needles by Yuqing Wang (110531)

“…According to former research, this is a time when global temperature decreased sharply. …”

Antioxidation and Anti-Inflammatory Activity of Prussian Blue Nanozymes to Alleviate Acetaminophen-Induced Acute Liver Injury by Qiang Feng (88137)

Subjects:

Downregulation of DOM decreases the abundance of PER and TIM. by Zhenxing Liu (399809)

“…Downregulation of DOM decreased PER levels at CT1-5 and CT17-21. (Scale bar: 50 um.) …”

Knockdown of S6K2 decreased Mcl-1. by Alakananda Basu (3842152)

Antibiotic use in animals (mg/kg/day) between 2015 and 2017. by Sarin Suwanpakdee (119683)

Host population bottlenecks decrease microbiome diversity. by Michael Ørsted (5926028)

SFRS7 acts as a tau exon 10 splicing enhancer in the glial cell-line U- 373 MG. by Daan van Abel (214754)

“…(C) Ratio numbers were obtained by dividing endogenous 4R and 3R tau mRNA concentrations from U373-MG cells transfected with siRNA SFRS7 or scrambled siRNA. …”

Extracellular adenosine modulates host-pathogen interactions through regulation of systemic metabolism during immune response in <i>Drosophila</i> by Adam Bajgar (730380)

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

Influence of stabilized MetA protein on the <i>E.coli</i> WE strain growth under stressful conditions. by Elena A. Mordukhova (646403)

Microstructure Evolution of the Mg-5.8 Zn-0.5 Zr-1.0 Yb Alloy During Homogenization by Lu Li (14069)

“…<div><p>The influence of homogenization treatment on microstructure evolution of Mg-5.8Zn-0.5Zr-1.0Yb (mass fraction, %) alloy was investigated under different annealing temperatures and holding times. …”

Linear decrease of delta power (1.1–5.0 Hz) across the first three sleep cycles in the cortical, hippocampal and scalp recordings. by Fabio Moroni (34208)

Compound CID 9998128 Is a Potential Multitarget Drug for Alzheimer’s Disease by Nguyen Quoc Thai (5348798)

“…Moreover, the compound dose-dependently decreases β-site amyloid precursor protein cleaving enzyme (BACE-1) activity with EC₅₀ value in micromolar range. …”

Compound CID 9998128 Is a Potential Multitarget Drug for Alzheimer’s Disease by Nguyen Quoc Thai (5348798)

“…Moreover, the compound dose-dependently decreases β-site amyloid precursor protein cleaving enzyme (BACE-1) activity with EC₅₀ value in micromolar range. …”