Image_4_Microvascular Dysfunction in Skeletal Muscle Precedes Myocardial Vascular Changes in Diabetic Cardiomyopathy: Sex-Dependent Differences.TIFF by Sadi Loai (12559255)

“…On echocardiography, all diabetic animals maintained normal ejection fraction and exhibited diastolic dysfunction, mild systolic dysfunction, and a slightly enlarged left ventricle. Exercise tolerance declined progressively and early in males (4 months), later in females (8 months); FMD showed lower baseline femoral arterial flow but unchanged reactivity in both sexes (5 months); and photoacoustic imaging showed lower tissue oxygen saturation in the legs of diabetic males (4 months) and diabetic females (10 months). …”

Image_3_Microvascular Dysfunction in Skeletal Muscle Precedes Myocardial Vascular Changes in Diabetic Cardiomyopathy: Sex-Dependent Differences.TIFF by Sadi Loai (12559255)

“…On echocardiography, all diabetic animals maintained normal ejection fraction and exhibited diastolic dysfunction, mild systolic dysfunction, and a slightly enlarged left ventricle. Exercise tolerance declined progressively and early in males (4 months), later in females (8 months); FMD showed lower baseline femoral arterial flow but unchanged reactivity in both sexes (5 months); and photoacoustic imaging showed lower tissue oxygen saturation in the legs of diabetic males (4 months) and diabetic females (10 months). …”

Image_6_Microvascular Dysfunction in Skeletal Muscle Precedes Myocardial Vascular Changes in Diabetic Cardiomyopathy: Sex-Dependent Differences.TIFF by Sadi Loai (12559255)

“…On echocardiography, all diabetic animals maintained normal ejection fraction and exhibited diastolic dysfunction, mild systolic dysfunction, and a slightly enlarged left ventricle. Exercise tolerance declined progressively and early in males (4 months), later in females (8 months); FMD showed lower baseline femoral arterial flow but unchanged reactivity in both sexes (5 months); and photoacoustic imaging showed lower tissue oxygen saturation in the legs of diabetic males (4 months) and diabetic females (10 months). …”

Image_7_Microvascular Dysfunction in Skeletal Muscle Precedes Myocardial Vascular Changes in Diabetic Cardiomyopathy: Sex-Dependent Differences.TIFF by Sadi Loai (12559255)

“…On echocardiography, all diabetic animals maintained normal ejection fraction and exhibited diastolic dysfunction, mild systolic dysfunction, and a slightly enlarged left ventricle. Exercise tolerance declined progressively and early in males (4 months), later in females (8 months); FMD showed lower baseline femoral arterial flow but unchanged reactivity in both sexes (5 months); and photoacoustic imaging showed lower tissue oxygen saturation in the legs of diabetic males (4 months) and diabetic females (10 months). …”

Peripheral Blood Proteins Distinguish IPF Patients from Controls by Ivan O Rosas (91093)

“…The magenta line labeled “Combined” is for the combinatorial classifier using all five markers. The identity line at 45 ° represents a marker that performed no better than classifying samples as IPF or control by flipping a fair coin.…”

High temperature environment reduces olive oil yield and quality by Yael Nissim (8754882)

“…In order to address the effect of high temperature environments on olive oil yield and quality, we compared its effect on the fruit development of five olive cultivars placed in a region noted for its high summer temperatures, with trees of the same cultivars placed in a region of relatively mild summers. …”

Cohesin Is Required for Activation of <em>MYC</em> by Estradiol by Miranda V. McEwan (121381)

Voluntary wheel running can lead to modulation of immune checkpoint molecule expression by Marie Lund Bay (9382997)

Vibration perception thresholds in age categories. by Linnéa Ekman (8138406)

“…<p>Mean values of vibration perception thresholds [dB] in 18 subjects for five different age categories of ten years. …”

Typical desialylated and α-1,6-fucosidase digested N-glycan profiles from gastric tumor and adjacent non-tumor tissue proteins. by Yun-Peng Zhao (551337)

“…Error bars represent 95%CI for means. (C) The value of peak7/peak5 is also decreased in tumor tissues, but the difference is not statistically significant.…”

Association of Inhaled Corticosteroids with Incident Pneumonia and Mortality in COPD Patients; Systematic Review and Meta-Analysis by Vikas Bansal (79044)

Loss of IRS2 promotes stromal activation and inhibits HSC reversion. by Fátima Manzano-Núñez (6273674)

“…(A) RT-qPCR analysis of LX-2 cells and primary hHSC cultures treated with vehicle (cont) or MitoC for 72 h prior to harvesting showing decreased <i>COL1A1</i> expression together with concomitant increase in HSC reversion marker HSPA1B (<i>n</i> = 3). …”

A 92-year-old female with 80% stenosis of left internal carotid artery received carotid stenting. by Han-Jui Lee (803878)

The concept of “triphosphate RNA balance”. by Joon H. Choi (9986900)

“…<p>Experiments with DUSP11 demonstrate that increasing or decreasing the cellular pool of 5′-PPP RNA modulates the sensitivity of the cell to activating the antiviral response. …”

Data_Sheet_3_Exploring the potential mechanism of Xiaojin Pill therapy for benign prostatic hyperplasia through metabolomics and gut microbiota analysis.zip by Yuying Yang (4111534)

“…Metabolomics studies have revealed 10 upregulated and 10 downregulated metabolites in treated rats, with 5-methylcytosine, uracil, and cytosine enriched in pyrimidine metabolism. …”

Data_Sheet_2_Exploring the potential mechanism of Xiaojin Pill therapy for benign prostatic hyperplasia through metabolomics and gut microbiota analysis.docx by Yuying Yang (4111534)

“…Metabolomics studies have revealed 10 upregulated and 10 downregulated metabolites in treated rats, with 5-methylcytosine, uracil, and cytosine enriched in pyrimidine metabolism. …”

Data_Sheet_4_Exploring the potential mechanism of Xiaojin Pill therapy for benign prostatic hyperplasia through metabolomics and gut microbiota analysis.docx by Yuying Yang (4111534)

“…Metabolomics studies have revealed 10 upregulated and 10 downregulated metabolites in treated rats, with 5-methylcytosine, uracil, and cytosine enriched in pyrimidine metabolism. …”

Data_Sheet_1_Exploring the potential mechanism of Xiaojin Pill therapy for benign prostatic hyperplasia through metabolomics and gut microbiota analysis.xls by Yuying Yang (4111534)

“…Metabolomics studies have revealed 10 upregulated and 10 downregulated metabolites in treated rats, with 5-methylcytosine, uracil, and cytosine enriched in pyrimidine metabolism. …”

DataSheet2_Availability and Accessibility of Orphan Medicinal Products to Patients in Slovakia in the Years 2010–2019.PDF by Tatiana Foltanova (12000908)

“…The average time for an orphan medicinal product to reach the Slovak market was almost 4 years, 43.5 months [6—202 months]. Together, 10.4% (8 815 patients) out of the theoretical patients’ estimation according to the prevalence in the orphan designation were treated with OMPs available in Slovakia.…”

DataSheet1_Availability and Accessibility of Orphan Medicinal Products to Patients in Slovakia in the Years 2010–2019.PDF by Tatiana Foltanova (12000908)

“…The average time for an orphan medicinal product to reach the Slovak market was almost 4 years, 43.5 months [6—202 months]. Together, 10.4% (8 815 patients) out of the theoretical patients’ estimation according to the prevalence in the orphan designation were treated with OMPs available in Slovakia.…”