Inhibition of PPARα by MEK1 relies on the nuclear export of MEK1 and not on MEK1 kinase activity. by Hamid el Azzouzi (318740)

“…(b) Luciferase measurements of NkL-Tag cells transiently transfected with a <i>mCPT</i> promoter driven reporter and co-transfected with PPARα-V5, MEK1 and MKP1, and stimulated 2 hours with Wy-14643 (1 µM) as indicated. …”

Effect of TCERG1 knockdown on the staurosporine-induced apoptotic pathway. by Marta Montes (812749)

“…(E) TCERG1 knockdown reduces annexin-V binding after staurosporine treatment. Control and TCERG1 knockdown (KD) Jurkat cells were incubated with annexin-V and analyzed by flow cytometry in the absence (-STAU) or in the presence of 0.5 μM staurosporine (+STAU) for 1 h. …”

Table_2_Severe thermal and major traumatic injury results in elevated plasma concentrations of total heme that are associated with poor clinical outcomes and systemic immune suppre... by Sebastian Tullie (18827107)

“…Non-survivors of burn injury and patients who developed sepsis, presented on day 1 with significantly elevated heme levels, with a difference of 6.5 µM in heme concentrations corresponding to a relative 52% increase in the odds of post-burn mortality. …”

Table_1_Severe thermal and major traumatic injury results in elevated plasma concentrations of total heme that are associated with poor clinical outcomes and systemic immune suppre... by Sebastian Tullie (18827107)

“…Non-survivors of burn injury and patients who developed sepsis, presented on day 1 with significantly elevated heme levels, with a difference of 6.5 µM in heme concentrations corresponding to a relative 52% increase in the odds of post-burn mortality. …”

Image_1_Severe thermal and major traumatic injury results in elevated plasma concentrations of total heme that are associated with poor clinical outcomes and systemic immune suppre... by Sebastian Tullie (18827107)

“…Non-survivors of burn injury and patients who developed sepsis, presented on day 1 with significantly elevated heme levels, with a difference of 6.5 µM in heme concentrations corresponding to a relative 52% increase in the odds of post-burn mortality. …”

Image_2_Severe thermal and major traumatic injury results in elevated plasma concentrations of total heme that are associated with poor clinical outcomes and systemic immune suppre... by Sebastian Tullie (18827107)

“…Non-survivors of burn injury and patients who developed sepsis, presented on day 1 with significantly elevated heme levels, with a difference of 6.5 µM in heme concentrations corresponding to a relative 52% increase in the odds of post-burn mortality. …”

Image_3_Severe thermal and major traumatic injury results in elevated plasma concentrations of total heme that are associated with poor clinical outcomes and systemic immune suppre... by Sebastian Tullie (18827107)

“…Non-survivors of burn injury and patients who developed sepsis, presented on day 1 with significantly elevated heme levels, with a difference of 6.5 µM in heme concentrations corresponding to a relative 52% increase in the odds of post-burn mortality. …”

High Glucose Variability Increases 30-Day Readmission Rates in Patients with Type 2 Diabetes Hospitalized in Department of Surgery by Ching-jung Hsieh (728756)

“…Comparing to control group, the study group also had higher HbA1c (8.4 ± 1.3% vs. 7.7 ± 1.1%, <i>p</i> = 0.015) and LOS (8.5± 2.5 days vs 7.0± 1.5 days, <i>p</i> = 0.020). …”

CRF1/CRF2 and MC3/MC4 Receptors Affect Glutamate- Induced Food Intake in Neonatal Meat-Type Chicken by F Ahmadi (6699116)

“…In experiment 6, the injections were (A) PBS, (B) MTII (MC3/MC4 receptor agonist, 2.5ng), (C) glutamate (75nmol) and (D) MTII+glutamate. …”

Data_Sheet_1_Electroacupuncture Pretreatment Alleviates Cerebral Ischemic Injury Through α7 Nicotinic Acetylcholine Receptor-Mediated Phenotypic Conversion of Microglia.pdf by Zhi Ma (244851)

“…The cell viability and lactate dehydrogenase (LDH) release of neurons co-cultured with microglia were analyzed using cell counting kit-8 (CCK-8) and LDH release assays. EA pretreatment decreased the expressions of M1 markers (iNOS, IL-1β, and CD86) and pro-inflammatory cytokines (TNF-α and IL-6), whereas it increased the expressions of M2 markers (Arg-1, TGF-β1, and CD206) and anti-inflammatory cytokines (IL-4 and IL-10) by activating α7nAChR. …”

The new earliest diverging Mesotheriinae (Mammalia, Notoungulata) from the Early Miocene (Burdigalian) of the Puna region, Catamarca, Argentina by Matías Alberto Armella (20758027)

DataSheet_1_Supplementation with myo-inositol and Selenium improves the clinical conditions and biochemical features of women with or at risk for subclinical hypothyroidism.pdf by Juraj Payer (11440015)

“…The TSH values significantly ameliorated along with the index of autoimmunity and the thyroid status. In a sub-class of patients, the auto-antibody titer decreased after myo-inositol + Selenium administration. …”

Data_Sheet_1_Analysis of Epigenetic Age Predictors in Pain-Related Conditions.PDF by Katarzyna Malgorzata Kwiatkowska (8950196)

“…Signs of premature aging have been associated with chronic pain, but few studies have investigated aging biomarkers in pain-related conditions. A set of DNA methylation (DNAm)-based estimates of age, called “epigenetic clocks,” has been proposed as biological measures of age-related adverse processes, morbidity, and mortality. …”

Image_7_Analysis of Epigenetic Age Predictors in Pain-Related Conditions.JPEG by Katarzyna Malgorzata Kwiatkowska (8950196)

“…Signs of premature aging have been associated with chronic pain, but few studies have investigated aging biomarkers in pain-related conditions. A set of DNA methylation (DNAm)-based estimates of age, called “epigenetic clocks,” has been proposed as biological measures of age-related adverse processes, morbidity, and mortality. …”

Image_1_Analysis of Epigenetic Age Predictors in Pain-Related Conditions.JPEG by Katarzyna Malgorzata Kwiatkowska (8950196)

“…Signs of premature aging have been associated with chronic pain, but few studies have investigated aging biomarkers in pain-related conditions. A set of DNA methylation (DNAm)-based estimates of age, called “epigenetic clocks,” has been proposed as biological measures of age-related adverse processes, morbidity, and mortality. …”

Image_6_Analysis of Epigenetic Age Predictors in Pain-Related Conditions.JPEG by Katarzyna Malgorzata Kwiatkowska (8950196)

“…Signs of premature aging have been associated with chronic pain, but few studies have investigated aging biomarkers in pain-related conditions. A set of DNA methylation (DNAm)-based estimates of age, called “epigenetic clocks,” has been proposed as biological measures of age-related adverse processes, morbidity, and mortality. …”

Image_9_Analysis of Epigenetic Age Predictors in Pain-Related Conditions.JPEG by Katarzyna Malgorzata Kwiatkowska (8950196)

“…Signs of premature aging have been associated with chronic pain, but few studies have investigated aging biomarkers in pain-related conditions. A set of DNA methylation (DNAm)-based estimates of age, called “epigenetic clocks,” has been proposed as biological measures of age-related adverse processes, morbidity, and mortality. …”

Image_2_Analysis of Epigenetic Age Predictors in Pain-Related Conditions.JPEG by Katarzyna Malgorzata Kwiatkowska (8950196)

“…Signs of premature aging have been associated with chronic pain, but few studies have investigated aging biomarkers in pain-related conditions. A set of DNA methylation (DNAm)-based estimates of age, called “epigenetic clocks,” has been proposed as biological measures of age-related adverse processes, morbidity, and mortality. …”

Image_3_Analysis of Epigenetic Age Predictors in Pain-Related Conditions.JPEG by Katarzyna Malgorzata Kwiatkowska (8950196)

“…Signs of premature aging have been associated with chronic pain, but few studies have investigated aging biomarkers in pain-related conditions. A set of DNA methylation (DNAm)-based estimates of age, called “epigenetic clocks,” has been proposed as biological measures of age-related adverse processes, morbidity, and mortality. …”

Image_4_Analysis of Epigenetic Age Predictors in Pain-Related Conditions.JPEG by Katarzyna Malgorzata Kwiatkowska (8950196)

“…Signs of premature aging have been associated with chronic pain, but few studies have investigated aging biomarkers in pain-related conditions. A set of DNA methylation (DNAm)-based estimates of age, called “epigenetic clocks,” has been proposed as biological measures of age-related adverse processes, morbidity, and mortality. …”