Hepatic protein expression as affected by NA and adipose protein expression as affected by time. by Asako Kinoshita (511938)

“…<p>A: The ratios of pooled groups (pool “NA” = HC-NA, LC-NA and pool “CON” = HC-CON, LC-CON, 24 or 0 g/d nicotinic acid from d1 to d21) were tested for the influence of nicotinic acid supplementation on the hepatic protein expression of PI3K and GLUT2 by one-way ANOVA (n = 10/group). …”

Schematic representation of the IL-11 mediated signaling and gene expression in JEG-3 and HTR-8/SVneo cells. by Pankaj Suman (336283)

“…In HTR-8/SVneo cells, IL-11 treatment increases the activation of STAT1(tyr701) and STAT3(tyr705) while, decreases the activation of ERK1/2. The increase in p-STAT3(tyr705) was associated with its nuclear localization within 10 min of IL-11 treatment. …”

Stit and the insulin receptor cooperate to activate the PI3K-I pathway. by Fergal O'Farrell (435865)

“…All images are thin (8 µm) confocal projections. Scale bars, 10 µm.</p>…”

DataSheet1_Curcumin supplementation increases longevity and antioxidant capacity in Caenorhabditis elegans.zip by Jianing Xu (123612)

“…<p>Curcumin is well known as a potent antioxidant and free radical scavenger and has great potential for anti-aging applications. …”

Data_Sheet_2_MicroRNA 3′ ends shorten during adolescent brain maturation.FASTA by Kristen T. Thomas (15288109)

“…We found that ~25% of miRNAs’ 3′ ends shorten with age due to increased 3′ trimming and decreased U tailing. Particularly, shorter but functionally competent isoforms (isomiRs) of miR-338-3p increase up to 10-fold during adolescence and only in brain. …”

The pool of premyelinating OL lineage cells is significantly increased following rHI; PreOLs are less susceptible to acute degeneration following rHI than following late HI. by Matthew W. Hagen (627944)

“…(D) Stereology further shows a decreased rate of preOL death following rHI relative to late HI (Kruskal-Wallis: H = 7.5, p = 0.057, on 3 df; mean ± SD Control: 0.9±0.4%; Early HI: 1.2±0.9%; Late HI: 5.0±2.4%; rHI: 1.7±1.8%; Bonferroni-corrected post-hoc Mann-Whitney U-tests: *Late HI vs. …”

Source Apportionment of Atmospheric Iron in Northern China Based on Three-Year Continuous Measurements by Tianle Zhang (21796679)

“…Results showed nearly 50% of Fe originated from anthropogenic sources, primarily industrial processes (30%) and coal combustion (17%). Although PM_2.5 concentrations decreased significantly, the Fe component of PM_2.5 did not show a significant decline. …”

Table_1_Successful treatment of refractory palmoplantar pustulosis by upadacitinib: report of 28 patients.DOC by Na Du (294594)

“…The mean age was (36.3 ± 10.5) years. After 12 weeks of treatment, PPPASI scores decreased from baseline (13.86 ± 2.76) to (5.56 ± 1.08), with a statistically significant difference (p < 0.05). …”

Antihypertensive Medication Classes Used among Medicare Beneficiaries Initiating Treatment in 2007–2010 by Shia T. Kent (463112)

“…<div><p>Background</p><p>After the 2003 publication of the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) guidelines, there was a 5–10% increase in patients initiating antihypertensive medication with a thiazide-type diuretic, but most patients still did not initiate treatment with this class. …”

From melanoma and nevus to volatile signatures. by Tatjana Abaffy (35871)

“…A peak of 2,5 dimethyl benzenamine is shown eluting at 17.8 min. …”

Table_1_Use of Prazosin for Pediatric Post-Traumatic Stress Disorder With Nightmares and/or Sleep Disorder: Case Series of 18 Patients Prospectively Assessed.docx by Vladimir Ferrafiat (9154643)

“…After 1 month of treatment with a mean prazosin dose of 2.16 ( ± 0.6) mg/day, the CGI-S score significantly decreased from 5.3 ( ± 0.9) to 2.9 ( ± 0.7) (improvement of 43%). …”

Supplementary Material for: Exposure to Air Pollution and Survival in follow-up After Hepatocellular Carcinoma by Chin W.-S. (12877004)

“…Conclusion: Our study suggests that long-term exposure to PM2.5 and NO2 was associated with decreased survival time in patients with HCC in Taiwan.…”

Dynamics of ammonia volatilization from NBPT-treated urea in tropical acid soils by Johnny Rodrigues Soares (15199662)

“…The treatments consisted of three soil pH levels and two N sources (UR and UR + NBPT), with five replicates. The soil pH values were adjusted and reached values of 4.5, 5.6, and 6.4 in the sandy-clay, and 4.5, 5.4, and 6.1 in the clay soil. …”

<i>Wolbachia w</i>AlbB triggers the differential expression of miRNAs in Aag2 <i>Ae</i>. <i>aegypti</i> cells. by Lingzhi She (11981756)

“…(D) qPCR analysis showed that the expression of 5 out of the top 15 downregulated DE miRNAs was decreased in whole-cell samples (left panel, two-sided t test, W-: n = 4, W+: n = 4, aae-miR-281-5p: <i>P</i> = 0.0036, aae-miR-252-5p: <i>P</i> = 0.0188, aae-miR-2a-3p: <i>P</i> = 0.0397, aae-miR-12-5p: <i>P</i> = 9.6512×10⁻⁷, aae-miR-1175-5p: <i>P</i> = 0.0043) and cytoplasm samples (right panel, two-sided t test, W-: n = 4, W+: n = 4, aae-miR-281-5p: <i>P</i> = 0.0291, aae-miR-252-5p: <i>P</i> = 0.0015, aae-miR-2a-3p: <i>P</i> = 0.0015, aae-miR-12-5p: <i>P</i> = 0.0006, aae-miR-1175-5p: <i>P</i> = 0.0015) from W+ cells in small RNA sequencing. …”

Ki67 immunostaining. by Juan Wen (173034)

“…(B)The Ki67 positive cells were counted. (* indicates the comparison between the compressive stress groups and the control group, * p<0.05, ** p<0.01; # indicates the comparison between the Sal/compressive stress groups and the compressive stress groups, # p<0.05, ## p<0.01)Apoptosis was examined using a TUNEL assay (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0155514#pone.0155514.g005" target="_blank">Fig 5A and 5B</a>). …”

<i>In vivo</i> imaging of mice infected intragastrically or intrarectally with luciferase-expressing <i>C</i>. <i>muridarum</i>. by Luying Wang (1492543)

“…<p>CBA/J mice were intragastrically (i.g., n = 5, panels a-i) or intrarectally (i.r., n = 5, j-r) inoculated with 5 x 10⁴ IFUs of luciferase-expressing <i>C</i>. …”

The <i>TRIT1</i> mutation disrupts modification activity on cytosolic and mitochondrial tRNAs but not enzyme abundance. by John W. Yarham (573109)

“…<p><b>A</b>) No decrease in the levels of the native TRIT1 protein in patient fibroblasts was observed by immunoblotting (using β-actin as a loading control) <b>B</b>) The isopentenyl modification status of both mitochondrial (mt-) and cytosolic (cy-) tRNAs in patient fibroblasts (lane P) compared to controls (lane C); by this approach a positive signal is due to lack of isopentenyl modification as detected by an anticodon loop (ACL) probe (the bulky modification on the N of adenine blocks base pairing with the probe, such that no signal for cy-tRNA^Ser(UGA) with the ACL probe indicates efficient modification in the control cells <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004424#pgen.1004424-Lamichhane2" target="_blank">[11]</a>); a body probe to a different region of the same tRNA is used as a control for calibration and calculation of steady-state levels. …”

Fluorometric Sniff-Cam (Gas-Imaging System) Utilizing Alcohol Dehydrogenase for Imaging Concentration Distribution of Acetaldehyde in Breath and Transdermal Vapor after Drinking by Kenta Iitani (4175995)

“…A reverse reaction of ADH was employed for detection of gaseous AcH where a relationship between fluorescence intensity from nicotinamide adenine dinucleotide and the concentration of AcH was inversely proportional; thus, the concentration distribution of AcH was measured by detecting the fluorescence decrease. …”

Image_2_Bidirectional Mendelian randomization study of insulin-related traits and risk of ovarian cancer.png by Xinghao Wang (802907)

“…</p>Results<p>Among all insulin related indicators (fasting insulin level, insulin secretion rate, peak insulin response), the insulin secretion rate was selected to have a causal relationship with the occurrence of ovarian cancer (IVW, P < 0.05), that is, the risk of ovarian cancer increased with the decrease of insulin secretion rate. …”

Image_4_Bidirectional Mendelian randomization study of insulin-related traits and risk of ovarian cancer.png by Xinghao Wang (802907)

“…</p>Results<p>Among all insulin related indicators (fasting insulin level, insulin secretion rate, peak insulin response), the insulin secretion rate was selected to have a causal relationship with the occurrence of ovarian cancer (IVW, P < 0.05), that is, the risk of ovarian cancer increased with the decrease of insulin secretion rate. …”