Image 1_Uptake of iron from ferrous fumarate can be mediated by clathrin-dependent endocytosis in Hutu-80 cells.tiff by Agata Tarczykowska (20620430)

“…Iron uptake (ferritin L) from ferrous fumarate (0.5 mM, 24 h) in DMT1 silenced cells was significantly decreased (60% ± 11%) in comparison to iron controls while a 1-h dose of ferrous fumarate (0.5 mM) significantly decreased ferritin L formation in the presence of the clathrin inhibitor chlorpromazine (61% ± 10%, in post-confluent cells and 37% ± 9% in non-confluent cells). …”

Table 1_Uptake of iron from ferrous fumarate can be mediated by clathrin-dependent endocytosis in Hutu-80 cells.docx by Agata Tarczykowska (20620430)

“…Iron uptake (ferritin L) from ferrous fumarate (0.5 mM, 24 h) in DMT1 silenced cells was significantly decreased (60% ± 11%) in comparison to iron controls while a 1-h dose of ferrous fumarate (0.5 mM) significantly decreased ferritin L formation in the presence of the clathrin inhibitor chlorpromazine (61% ± 10%, in post-confluent cells and 37% ± 9% in non-confluent cells). …”

Data_Sheet_1_Mitochondrial Deficits With Neural and Social Damage in Early-Stage Alzheimer’s Disease Model Mice.docx by Afzal Misrani (10258750)

“…We observed increased levels of mitochondrial fission protein, Drp1, and decreased levels of ATP synthase subunit, ATP5A, leading to abnormal mitochondrial morphology, increased oxidative stress, glial activation, apoptosis, and altered neuronal morphology as early as 4∼5 months of age in APP/PS1 mice. …”

Pattern convergence via scaling in single granule cells. by Antoine D. Madar (6619286)

“…<b>(A)</b> <i>Left</i>: Input set A was constituted of spike trains following a Poisson distribution, each with a different firing rate (FR), increased from 7 to 31.5 Hz, but with an average R_input constrained around 0.75 (τ_w = 10 ms). …”

Template-Directed Ligation of Tethered Mononucleotides by T4 DNA Ligase for Kinase Ribozyme Selection by David G. Nickens (243216)

“…</p><h3>Methodology/Principal Findings</h3><p>This study demonstrates the ability of T4 DNA ligase to capture RNA strands in which a tethered monodeoxynucleoside has acquired a 5′ phosphate. …”

Influence of and on the Relative Concentration of Splicing Proteins in Nuclear Speckles by José Rino (81063)

“…The ratio increases with decreasing values, but stabilizes below a threshold of approximately 10^−1.5 s⁻¹. …”

Image_3_Agronomic, Physiological and Genetic Changes Associated With Evolution, Migration and Modern Breeding in Durum Wheat.TIF by Conxita Royo (2938401)

“…Alleles in chromosomes 5A and 7A detected in landraces were associated with decreased yield. …”

Image_1_Agronomic, Physiological and Genetic Changes Associated With Evolution, Migration and Modern Breeding in Durum Wheat.TIF by Conxita Royo (2938401)

“…Alleles in chromosomes 5A and 7A detected in landraces were associated with decreased yield. …”

Image_2_Agronomic, Physiological and Genetic Changes Associated With Evolution, Migration and Modern Breeding in Durum Wheat.tif by Conxita Royo (2938401)

“…Alleles in chromosomes 5A and 7A detected in landraces were associated with decreased yield. …”

Image_1_Effect of High-Intensity Interval Training on Body Composition, Cardiorespiratory Fitness, Blood Pressure, and Substrate Utilization During Exercise Among Prehypertensive a... by Pedro Delgado-Floody (9534113)

“…Groups were distributed based on their baseline BP: HIIT-hypertensive (H-HTN: age 47.7 ± 12.0 years; body mass index [BMI] 30.3 ± 5.5 kg/m²; systolic [SBP]/diastolic BP [DBP] 151.6 ± 10/81.9 ± 4.2 mmHg), HIIT-pre-hypertensive (H-PreHTN: age 37.6 ± 12.0 years; BMI 31.9 ± 5.3 kg/m²; SBP/DBP 134.4 ± 3.2/74.9 ± 7.0 mmHg), and a normotensive control group (H-CG: age 40.7 ± 11.0 years; BMI 29.5 ± 4.2 kg/m²; SBP/DBP 117.0 ± 6.2/72.4 ± 4.1 mmHg). …”

Data Sheet 1_Dietary resveratrol and β-Hydroxy-β-Methylbutyric acid enhance flavor and modulate intramuscular fat in Tibetan sheep: insights from transcriptomics and lipidomics.zip... by Xuan Chen (158617)

“…Transcriptomic analysis revealed that RES and HMB synergistically regulated the Calcium (ERBB4, P2RX7, ERBB3, P2RX3, and SLC8A1), Hippo (WNT9A, WNT10B, WNT6, and WNT2B), Estrogen (HSP90AA1, TGFA, and RARA), and Arachidonic acid (PLA2G4A, ALOX12, and PTGDS) signaling pathways, collectively promoting muscle cell proliferation and differentiation, Metabolomics identified key lipid molecules (LPC(20:0/20:1), PC(21:2/37:0/38:5)) and pathways (Glycerophospholipid, Arachidonic acid metabolism) contributing to flavor optimization. …”

Oral Tolerance to Environmental Mycobacteria Interferes with Intradermal, but Not Pulmonary, Immunization against Tuberculosis by Dominique N. Price (2432452)

“…After intradermal BCG immunization in mice exposed to oral <i>M</i>. <i>avium</i>, we saw a significant decrease in the pro-inflammatory cytokine IFN-γ, and an increase in T regulatory cells and the immunosuppressive cytokine IL-10 compared to naïve BCG-vaccinated animals. …”

Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis by Lorena Fernandez-Mosquera (5077820)

“…</p> <p><b>Abbreviation</b>: ΔΨ_m: mitochondrial transmembrane potential; AMP: adenosine monophosphate; AMPK: AMP-activated protein kinase; ATG5: autophagy related 5; ATP: adenosine triphosphate; ATP6V0A1: ATPase, H+ transporting, lysosomal, V0 subbunit A1; ATP6V1A: ATPase, H+ transporting, lysosomal, V0 subbunit A; BSA: bovine serum albumin; CCCP: carbonyl cyanide-m-chlorophenylhydrazone; CREB1: cAMP response element binding protein 1; CTSD: cathepsin D; CTSF: cathepsin F; DMEM: Dulbecco’s modified Eagle’s medium; DMSO: dimethyl sulfoxide; EBSS: Earl’s balanced salt solution; ER: endoplasmic reticulum; FBS: fetal bovine serum; FCCP: carbonyl cyanide-p-trifluoromethoxyphenolhydrazone; GFP: green fluorescent protein; GPN: glycyl-L-phenylalanine 2-naphthylamide; LAMP1: lysosomal associated membrane protein 1; MAP1LC3B/LC3B: microtubule associated protein 1 light chain 3 beta; MCOLN1/TRPML1: mucolipin 1; MEF: mouse embryonic fibroblast; MITF: melanocyte inducing transcription factor; ML1N*2-GFP: probe used to detect PtdIns(3,5)P₂ based on the transmembrane domain of MCOLN1; MTORC1: mechanistic target of rapamycin kinase complex 1; NDUFS4: NADH:ubiquinone oxidoreductase subunit S4; OCR: oxygen consumption rate; PBS: phosphate-buffered saline; pcDNA: plasmid cytomegalovirus promoter DNA; PCR: polymerase chain reaction; PtdIns3P: phosphatidylinositol-3-phosphate; PtdIns(3,5)P₂: phosphatidylinositol-3,5-bisphosphate; PIKFYVE: phosphoinositide kinase, FYVE-type zinc finger containing; P/S: penicillin-streptomycin; PVDF: polyvinylidene fluoride; qPCR: quantitative real time polymerase chain reaction; RFP: red fluorescent protein; RNA: ribonucleic acid; SDS-PAGE: sodium dodecyl sulfate polyacrylamide gel electrophoresis; shRNA: short hairpin RNA; siRNA: small interfering RNA; TFEB: transcription factor EB; TFE3: transcription factor binding to IGHM enhancer 3; TMRM: tetramethylrhodamine, methyl ester, perchlorate; ULK1: unc-51 like autophagy activating kinase 1; ULK2: unc-51 like autophagy activating kinase 2; UQCRC1: ubiquinol-cytochrome c reductase core protein 1; v-ATPase: vacuolar-type H+-translocating ATPase; WT: wild-type</p>…”

MAC and RYT treatments evolved different metabolite production and consumption profiles. by Nerve Zhou (3830020)

“…<i>cerevisiae</i> CEN.PK113-7D (0.38g/L) [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0173318#pone.0173318.ref037" target="_blank">37</a>] has 1.83 fold higher ethanol yield than the <i>L</i>. …”

Inx2 is required for border cell (BC) fate specification. by Aresh Sahu (3692557)

“…<p>(A, B, G, H): Stage 9–10 egg chambers of indicated genotypes. …”

HCMV induces secretion of IL-6 by HepG2 cells and PHH. by Quentin Lepiller (394353)

“…IE1 pp72 antigen expression was measured up to day 3 postinfection by Western blotting, as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0059591#s2" target="_blank">Materials and Methods</a> section. beta-actin was used as control. …”

Data_Sheet_1_Whey Protein Lipid Concentrate High in Milk Fat Globule Membrane Components Inhibit Porcine and Human Rotavirus in vitro.PDF by Marcia H. Monaco (11371794)

“…</p><p>Materials and Methods: Confluent cells were exposed to OSU or Wa RV in the presence of WPLC or WPC (control) at 0, 0.1, 0.5, 1.0, 2.5, or 5 mg/ml. Infectivity was detected by immunohistochemistry and expressed as % inhibition relative to 0 mg/ml. …”

Table_1_Whey Protein Lipid Concentrate High in Milk Fat Globule Membrane Components Inhibit Porcine and Human Rotavirus in vitro.DOCX by Marcia H. Monaco (11371794)

“…</p><p>Materials and Methods: Confluent cells were exposed to OSU or Wa RV in the presence of WPLC or WPC (control) at 0, 0.1, 0.5, 1.0, 2.5, or 5 mg/ml. Infectivity was detected by immunohistochemistry and expressed as % inhibition relative to 0 mg/ml. …”

Presentation 1_Effects of temperature, pressure, and hydration on the microstructural characteristics and mechanical properties of calcite.pdf by Xiaoyi Zhou (8603268)

“…When the pressure increases from 0.1 GPa to 0.5 GPa, the volume of calcite crystal decreases by 1.10%, while the bulk modulus, shear modulus and Young’s modulus increase by 2.74%, 9.36% and 8.66%, respectively. …”

Distribution of weight loss and long-term follow-up. by Christina T. Rieger (838986)

“…<p>A: App. 40% of patients decreased < 5% of BMI (considered not significant), but the majority lost ≥ 5% of BMI during SCT. …”