Indoxyl sulfate and <i>p</i>-cresol sulfate activated the renin–angiotensin–aldosterone system in vitro. by Chiao-Yin Sun (174213)

“…IS and PCS at concentrations of 1, 5, and 50 mg/L significantly decreased AT2 receptor protein expression <i>in vitro</i>. …”

Inactivation of <em>Wolbachia</em> Reveals Its Biological Roles in Whitefly Host by Xia Xue (123975)

“…Inactivation was associated with a significant decrease in the body size of the 4^th instar which leads us to speculate as to whether <em>Wolbachia</em> may have a nutrient supplementation role. …”

DNA epitope vaccine improves acquisition and retention of spatial memory in immune mice. by Nina Movsesyan (86328)

“…<p>A) The escape latency to reach the platform was significantly decreased in the groups of non-transgenic (n = 6) and 3xTg-AD immune mice (n = 9) versus age-matched groups of MDC-irrelevant control (n = 5) and non-vaccinated control 3xTg-AD mice (n = 5). …”

Picroside II attenuates ischemia/reperfusion testicular injury by alleviating oxidative stress and apoptosis through reducing nitric oxide synthesis by Yanze Li (8185077)

“…The activities of HO-1, MPO, NOX, XO and MDA content were increased and the SOD activity was decreased in l/R (P<0.05) and could be reversed by Picroside II (P=0.03, 405.5±7.5 vs. 304±17U/mgprot; P=0.02, 0.99±0.05 vs. 0.52±0.04 mgprot; P=0.01, 260+7 vs. 189±2 mgprot; P=0.04, 10.95+0.55 vs. 8.75+0.35 U/mgprot; P=0.045, 6.8+0.7 vs. 3.75+0.35 mgprot; P=0.04, 44.5+3.5 vs. 57.5+3.5 mgprot). …”

Image_7_Tilapia Piscidin 4 (TP4) Reprograms M1 Macrophages to M2 Phenotypes in Cell Models of Gardnerella vaginalis-Induced Vaginosis.jpeg by Chia-Wen Liu (708076)

“…Further, we found that direct treatment with TP4 switched M1 macrophages toward a resolving M2c phenotype via the MAPK/ERK pathway and IL-10-STAT3 signaling. …”

DataSheet_1_The sparing effect of ultra-high dose rate irradiation on the esophagus.docx by Wenting Ren (4162672)

“…Label-free quantitative proteomic analysis revealed that the sparing effect observed in the FLASH group may be attributed to a reduction in radiation-induced protein damage associated with mitochondrial functions, including proteins involved in the tricarboxylic acid cycle and oxidative phosphorylation, as well as a decrease in acute inflammatory responses.…”

Image_4_Tilapia Piscidin 4 (TP4) Reprograms M1 Macrophages to M2 Phenotypes in Cell Models of Gardnerella vaginalis-Induced Vaginosis.jpeg by Chia-Wen Liu (708076)

“…Further, we found that direct treatment with TP4 switched M1 macrophages toward a resolving M2c phenotype via the MAPK/ERK pathway and IL-10-STAT3 signaling. …”

Image_1_Tilapia Piscidin 4 (TP4) Reprograms M1 Macrophages to M2 Phenotypes in Cell Models of Gardnerella vaginalis-Induced Vaginosis.jpeg by Chia-Wen Liu (708076)

“…Further, we found that direct treatment with TP4 switched M1 macrophages toward a resolving M2c phenotype via the MAPK/ERK pathway and IL-10-STAT3 signaling. …”

Image_6_Tilapia Piscidin 4 (TP4) Reprograms M1 Macrophages to M2 Phenotypes in Cell Models of Gardnerella vaginalis-Induced Vaginosis.jpeg by Chia-Wen Liu (708076)

“…Further, we found that direct treatment with TP4 switched M1 macrophages toward a resolving M2c phenotype via the MAPK/ERK pathway and IL-10-STAT3 signaling. …”

Table_1_Tilapia Piscidin 4 (TP4) Reprograms M1 Macrophages to M2 Phenotypes in Cell Models of Gardnerella vaginalis-Induced Vaginosis.docx by Chia-Wen Liu (708076)

“…Further, we found that direct treatment with TP4 switched M1 macrophages toward a resolving M2c phenotype via the MAPK/ERK pathway and IL-10-STAT3 signaling. …”

Image_3_Tilapia Piscidin 4 (TP4) Reprograms M1 Macrophages to M2 Phenotypes in Cell Models of Gardnerella vaginalis-Induced Vaginosis.jpeg by Chia-Wen Liu (708076)

“…Further, we found that direct treatment with TP4 switched M1 macrophages toward a resolving M2c phenotype via the MAPK/ERK pathway and IL-10-STAT3 signaling. …”

Image_2_Tilapia Piscidin 4 (TP4) Reprograms M1 Macrophages to M2 Phenotypes in Cell Models of Gardnerella vaginalis-Induced Vaginosis.jpeg by Chia-Wen Liu (708076)

“…Further, we found that direct treatment with TP4 switched M1 macrophages toward a resolving M2c phenotype via the MAPK/ERK pathway and IL-10-STAT3 signaling. …”

Summary of key results. by John R. Houser (783591)

“…On the other hand, relative levels of mRNA decreased upon entry to stationary phase perhaps as a strategy for reducing overall protein synthesis. …”

Effect of Telomerase Depletion on the Differentiation of Human CD34+ Progenitor Cells. by Aparna Raval (14624)

“…<p>(A-B) Scatter plots showing median values for (A) pRb and (B) pATM expression in CD34-LKS CD150hi, CD150lo and CD150neg populations from WT <i>Tert</i>+/+ (n = 4), G0 <i>Tert</i>+/- (n = 4), G5 <i>Tert</i>-/- (n = 4) and TxG5 <i>Tert</i>-/- (n = 4) mice. …”

Polymorphisms in the <i>MASP1</i> Gene Are Associated with Serum Levels of MASP-1, MASP-3, and MAp44 by Christian Gytz Ammitzbøll (116780)

“…Being e.g. homozygote for the minor allele of rs3774275 was associated with an increase in median concentration of 13% in MASP-1(P=0.03), 29% in MAp44 (P<0.001), and a decrease in MASP-3 of 26% (P<0.001) compared to homozygosis for the major allele. …”

Simulation of SMARD experiment with comparison to rate-equation estimates. by Michel G. Gauthier (152223)

“…Each line corresponds to a molecule as the example presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0032053#pone-0032053-g005" target="_blank">Fig. 5 b</a>. …”

Table_15_Transcriptome characteristics during cell wall formation of endosperm cellularization and embryo differentiation in Arabidopsis.xlsx by Chengcheng Li (2591632)

“…Here, we characterized the early embryo and endosperm development of the naa15 mutant that had abnormal embryo differentiation and incomplete endosperm cellularization compared to WT of Arabidopsis, and comparatively investigated the changes of gene expressions in WT seeds at 3, 4, and 5 days after pollination (3W, 4W, and 5W) and the white homozygous aborted naa15 seeds at 5, 6, and 7 DAP (5M, 6M, and 7M) from naa15-1/+ siliques using RNA sequencing and qPCR assays. …”

Table_2_Transcriptome characteristics during cell wall formation of endosperm cellularization and embryo differentiation in Arabidopsis.xlsx by Chengcheng Li (2591632)

“…Here, we characterized the early embryo and endosperm development of the naa15 mutant that had abnormal embryo differentiation and incomplete endosperm cellularization compared to WT of Arabidopsis, and comparatively investigated the changes of gene expressions in WT seeds at 3, 4, and 5 days after pollination (3W, 4W, and 5W) and the white homozygous aborted naa15 seeds at 5, 6, and 7 DAP (5M, 6M, and 7M) from naa15-1/+ siliques using RNA sequencing and qPCR assays. …”

Table_7_Transcriptome characteristics during cell wall formation of endosperm cellularization and embryo differentiation in Arabidopsis.xls by Chengcheng Li (2591632)

“…Here, we characterized the early embryo and endosperm development of the naa15 mutant that had abnormal embryo differentiation and incomplete endosperm cellularization compared to WT of Arabidopsis, and comparatively investigated the changes of gene expressions in WT seeds at 3, 4, and 5 days after pollination (3W, 4W, and 5W) and the white homozygous aborted naa15 seeds at 5, 6, and 7 DAP (5M, 6M, and 7M) from naa15-1/+ siliques using RNA sequencing and qPCR assays. …”

Hemodynamic effects of high-dose ephedrine in anesthetized rats. by Daniel Radiloff (588253)

“…C: Repeated injection of combined ephedrine (20 mg/kg) and ambrisentan (0.1 mg/kg) significantly enhances heart rates, and concomitantly, pulmonary blood flow, measured by pulmonary window blood flow measurements, and pulse oximetry (paired T-test, corrected for multiple comparison, p<0.05, N = 5). D: injection of ephedrine, alone or in combination with ambrisentan, caused a significant increase of breathing rates (one-sided ANOVA with Bonferroni correction, p<0.001, N = 5–13/group). …”