Image_1_Divergent Effects of the N-Methyl-D-Aspartate Receptor Antagonist Kynurenic Acid and the Synthetic Analog SZR-72 on Microcirculatory and Mitochondrial Dysfunction in Experi... by László Juhász (9406387)

“…</p><p>Results: Sepsis was characterized by an increased ROFA score (5.3 ± 1.3 vs. 1.3 ± 0.7), increased ET-1, IL-6, NT and XOR levels, and decreased serosal PPV (65 ± 12% vs. 87 ± 7%), ΔΨmt and CI–CII-linked OXPHOS (73 ± 16 vs. 158 ± 14, and 189 ± 67 vs. 328 ± 81, respectively) as compared to controls. …”

Image_1_Multi-System Adaptation to Confinement During the 180-Day Controlled Ecological Life Support System (CELSS) Experiment.jpeg by Ming Yuan (90012)

“…Carotid intima-media thickness (IMT) increased by 10–15%. Endothelium-dependent vasodilation decreased. …”

Image_3_Multi-System Adaptation to Confinement During the 180-Day Controlled Ecological Life Support System (CELSS) Experiment.jpeg by Ming Yuan (90012)

“…Carotid intima-media thickness (IMT) increased by 10–15%. Endothelium-dependent vasodilation decreased. …”

Image_4_Multi-System Adaptation to Confinement During the 180-Day Controlled Ecological Life Support System (CELSS) Experiment.jpeg by Ming Yuan (90012)

“…Carotid intima-media thickness (IMT) increased by 10–15%. Endothelium-dependent vasodilation decreased. …”

Data_Sheet_1_Multi-System Adaptation to Confinement During the 180-Day Controlled Ecological Life Support System (CELSS) Experiment.zip by Ming Yuan (90012)

“…Carotid intima-media thickness (IMT) increased by 10–15%. Endothelium-dependent vasodilation decreased. …”

Image_2_Multi-System Adaptation to Confinement During the 180-Day Controlled Ecological Life Support System (CELSS) Experiment.jpeg by Ming Yuan (90012)

“…Carotid intima-media thickness (IMT) increased by 10–15%. Endothelium-dependent vasodilation decreased. …”

image1_Changes in Efficacy Indicators for Adalimumab Biosimilar Candidate (HS016) for the Treatment of Active Ankylosing Spondylitis at Various Time Points.tif by Jinmei Su (4604059)

“…</p><p>Results: This subanalysis revealed no significant difference between the patient groups treated with HS016 or adalimumab for any individual efficacy indicator investigated at any time point (all p > 0.05) beside faster total back pain score improvements in the adalimumab group on week 10, 12 and 22, which became equal at week 24. Among these indicators, chest expansion showed a significant increase at each time point compared with baseline, whereas all other efficacy indicators showed significant decreases compared with baseline at each time point (all p < 0.05). …”

The Prognostic Significance of Metabolic Response Heterogeneity in Metastatic Colorectal Cancer by Alain Hendlisz (801785)

“…<div><p>Background</p><p>Tumoral heterogeneity is a major determinant of resistance in solid tumors. …”

Data_Sheet_1_Synthetic Fluid Inclusions XXIV. In situ Monitoring of the Carbonation of Olivine Under Conditions Relevant to Carbon Capture and Storage Using Synthetic Fluid Inclusi... by Eszter Sendula (2822699)

“…Results show a measurable decrease of CO₂ density in the fluid inclusions as a result of the reaction between the CO₂-bearing seawater-like aqueous solution and olivine. …”

<i>ACVR2</i> promoter hypermethylation and LOH in colon cancer specimens and the MSS HT29 cell line and correlation of <i>ACVR2</i> promoter hypermethylation and loss of <i>ACVR2</... by Barbara Jung (155690)

“…C) Six colon cancer cell lines with different microsatellite instability backgrounds (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0008308#pone-0008308-t003" target="_blank">Table 3</a>) were analyzed for ACVR2 protein expression using immunoprecipitation techniques. …”

Interruption of CXCL13-CXCR5 Axis Increases Upper Genital Tract Pathology and Activation of NKT Cells following Chlamydial Genital Infection by Janina Jiang (117561)

“…After resolution, we noted increased fibrosis and the accumulation of a variety of T cells subsets (CD4-IFNγ, CD4-IL-17, CD4-IL-10 & CD8-TNFα) in the oviducts. …”

Additional file 1 of Deficiency in nucleoside diphosphate kinase B leads to endothelial activation of the hexosamine biosynthesis pathway and cardiac dysfunction by Feng Shao (112229)

“…Statistical analysis of GTT (A) and blood insulin levels after GTT (B) in NDPKB-/- mice. …”

Methylation profiling in control and Tet tcKO retinas. Related to Fig 6. by Ismael Hernández-Núñez (10128242)

“…<b>(I, J)</b> Line plots showing correlation coefficients of P21 Tet tcKO or Cre− control WGBS with temporal WGBS methylation profiles across (I) accessible DNA and (J) promoters for ATAC peaks that display a >10% decrease in methylation levels across development. …”

Enhancement of neurodegeneration, actin rod formation, Drp1 mislocalization, and mitochondrial elongation in mice expressing human tau and human LRRK2. by Farah H. Bardai (6107924)

“…(E) Representative immunofluorescence images showing actin rods in the brains of transgenic mice. Scale bars represent 10 μm. (F) Immunofluorescence images of mouse hippocampal neurons stained for ATPVa to visualize the mitochondria and Drp1 show a decrease in Drp1 localization to mitochondria in human tau transgenic mice and a further reduction in tau—LRRK2 mice. …”

Table_1_Exploring candidate biomarkers for rheumatoid arthritis through cardiovascular and cardiometabolic serum proteome profiling.docx by Laura Cuesta-López (17963900)

“…Methotrexate treatment significantly reduced the levels of 13 proteins, while tofacitinib therapy modulated the expression of 10 proteins. These reductions were associated with a decrease in DAS28. …”

Image_1_Exploring candidate biomarkers for rheumatoid arthritis through cardiovascular and cardiometabolic serum proteome profiling.tiff by Laura Cuesta-López (17963900)

“…Methotrexate treatment significantly reduced the levels of 13 proteins, while tofacitinib therapy modulated the expression of 10 proteins. These reductions were associated with a decrease in DAS28. …”

Table_1_Macromineral requirements for maintenance and growth in male and female hair sheep.docx by Caio J. L. Herbster (14703109)

“…The chosen models explained the observed variability in the sex, and the choices were based on a low level of uncertainty (w ≥ 0.90). Irrespective of sex, NCa_g and NP_g decreased with increasing BW from 10 to 30 kg and average daily gain (ADG) of 150 g/day, ranging from 1.71–1.38; 1.83–1.57; 1.82–1.51 of Ca and 0.86–0.66; 0.92–0.78; 0.92–0.75 of P for non-castrated males, castrated males, and females, respectively. …”

Fig 4 - by Yu Feng (445691)

“…<p>(A) Comparison between the storage capacity of Markovian binary synapses and binarized double well synapses defined in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1011354#pcbi.1011354.e043" target="_blank">Eq (12)</a>. …”

Toll signaling in the Drosophila larval fat body shifts programs of anabolic lipid metabolism and dysregulates nutrient storage by Brittany Martínez (8728753)

“…Expression of Toll^10b in the fat body leads to a tissue-autonomous decrease in triglyceride levels. …”

Functional and misfolded NTS1 during purification. by Jim F. White (361948)

“…</p>1<p>The amount of functional NTS1 in the NiE, NTFT and NTE fractions was determined by [³H]NT binding (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0012579#pone-0012579-t003" target="_blank">Tables 3</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0012579#pone-0012579-t004" target="_blank">4</a>). …”