Selenium-Based <i>S</i>-Adenosylmethionine Analog Reveals the Mammalian Seven-Beta-Strand Methyltransferase METTL10 to Be an EF1A1 Lysine Methyltransferase by Tadahiro Shimazu (619411)

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ProSeAM, a synthetic SAM analog, has a wide spectrum of reactivity for histones and non-histone substrates. by Tadahiro Shimazu (619411)

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METTL10 knockdown reduces the level of lysine 318 methylation in EF1A1 <i>in vivo</i>. by Tadahiro Shimazu (619411)

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Laminar flow increases the expression of anti-oxidant genes and decreases the inflammatory basal state of GEnC. by Daan C. ‘t Hart (10751645)

DataSheet_1_microRNA-144/451 decreases dendritic cell bioactivity via targeting interferon-regulatory factor 5 to limit DSS-induced colitis.pdf by Zhijie Lin (173992)

“…Mechanistically, the miR-144 directly targets the 3`-UTR of IRF5 and represses the expression of IRF5 in DCs. …”

TGF-β₁ decreased soluble FBLN-1 from human ASM cells. by Ling Chen (25698)

CFG decreases TGF- β 1-induced invasion and migration of HEY and SKOV3 cells in vitro. by Fangfang Tao (408131)

Data Sheet 1_Probiotic Limosilactobacillus reuteri KUB-AC5 decreases urothelial cell invasion and enhances macrophage killing of uropathogenic Escherichia coli in vitro study.pdf by Arishabhas Tantibhadrasapa (13929639)

“…The human bladder epithelial cell line UM-UC-3 was used to assess the adhesion and pathogen-attachment inhibition properties of AC5 on UPEC.</p>Results and discussion<p>Our data showed that AC5 can attach to UM-UC-3 and decrease UPEC attachment in a dose-dependent manner. …”

TGFβ receptor reconstitution leads to decreased metastatic colonization: Impact on TGFβ/PKA signaling. by Sanjib Chowdhury (222280)

Systemic injection of an H4 receptor agonist induces a decrease in CREB and pCREB levels in the cerebellar vermis and prefrontal cortex in mice by C.E.M. Fernandes (6673289)

Cellular levels of PIP2 and PIP3 were significantly decreased by Tipe2-deficient macrophages. by Ruiling Liu (507091)

Table1_Apoptotic volume decrease (AVD) in A549 cells exposed to water-soluble fraction of particulate matter (PM10).DOCX by M. E. Giordano (16517169)

“…In particular, the study addressed if PM₁₀ exposure can be a main factor in the induction of the Apoptotic Volume Decrease (AVD), which is one of the first events of apoptosis, and if the generation of intracellular oxidative stress can be involved in the PM₁₀ induction of apoptosis in A549 cells. …”

Everolimus decreased EC inflammation via lowered IL-1β and IL-6 expression in ECs. by Zsolt Fejes (844136)

Longitudinal analysis of exploratory behavior during housing in Marlau™ cages is in favor of decreased anxiety in “enriched” rats. by Raafat P. Fares (288906)

A-C. Inhibitors of cell death (zVAD-fmk and Nec-1) do not rescue the BMP2-induced decrease in cell numbers. by Charlotte Lagler (4017212)

Hyperlipidemia-Associated Renal Damage Decreases Klotho Expression in Kidneys from ApoE Knockout Mice by Cristina Sastre (503532)

“…Hyperlipidemia accelerates the progression of renal damage, but the mechanisms of the deleterious effects of hyperlipidemia remain unclear.</p><p>Methods</p><p>We evaluated whether hyperlipidemia modulates Klotho expression in kidneys from C57BL/6 and hyperlipidemic apolipoprotein E knockout (ApoE KO) mice fed with a normal chow diet (ND) or a Western-type high cholesterol-fat diet (HC) for 5 to 10 weeks, respectively.…”

Table_5_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

FEF inactivation decreased ipsilesional and contralesional microsaccade peak velocities, both before and after cue onset. by Tyler R. Peel (2935848)

“…<p>(<b>A</b>) Unilateral (left) FEF inactivation reduced peak velocity for contralesional microsaccades independently of amplitude in our example monkey DZ and also decreased peak velocities for ipsilesional microsaccades. …”

Image_5_Consecutive Hypoxia Decreases Expression of NOTCH3, HEY1, CC10, and FOXJ1 via NKX2-1 Downregulation and Intermittent Hypoxia-Reoxygenation Increases Expression of BMP4, NOTCH1, MKI67, OCT4, and MUC5AC via HIF1A Upregulation in Human Bronchial Epithelial Cells.TIF by Yung-Yu Yang (9343376)

“…Inhibition of HIF1A or NKX2-1 expression by siRNA transfection respectively decreased BMP4/NOTCH1/MKI67/OCT4/MUC5AC and NOTCH3/HEY1/CC10/FOXJ1 expression in the HBE cells cultured under intermittent H/R to the same levels under normoxia. …”

Supplementary Material for: Clinical Implications of Decreased Computed Tomography Value after Ramucirumab in Advanced Gastric Cancer by Izawa N. (6834062)

“…<b><i>Results:</i></b> Ten (90.9%) of 11 patients in the RAM arm and 18 (54.5%) of 33 patients in the TAX arm showed decreased CT values. …”