Effect of compound 4f on (A) Platelet aggregation induced by Collagen/ADP/Epinephrine and (B) Platelet adhesion on immobilized collagen type I with compound 4f pre-treated collagen... by Kodagahalli S. Rakesh (631835)

A Shotgun Proteomic Approach Reveals That Fe Deficiency Causes Marked Changes in the Protein Profiles of Plasma Membrane and Detergent-Resistant Microdomain Preparations from <i>Be... by Elain Gutierrez-Carbonell (1796647)

“…Functional categorization of these proteins showed that signaling and general and vesicle-related transport accounted for approximately 50% of the differences in both PM and DRM, indicating that from a qualitative point of view changes induced by Fe deficiency are similar in both preparations. …”

Pros and cons of insulin administration on liver glucose metabolism in strength-trained healthy mice by V.A.R. Pereira (6304466)

“…Lactate and pyruvate release were reduced to a half by training. The greater gluconeogenesis from alanine+glutamine induced by training (TS +50%) was reversed by insulin (TI). …”

The effect of systemic injection of dopaminergic antagonists of D1- and D2-like receptors on the pattern of responses evoked by cortical stimulation in a SNr neuron is reversed by... by Nicolas Maurice (504005)

“…The same number of cortical stimulations (red bar, n = 50) was applied in <b><i>A-C</i></b>.</p>…”

DataSheet1_Sodium Tanshinone IIA Sulfonate as a Potent IDO1/TDO2 Dual Inhibitor Enhances Anti-PD1 Therapy for Colorectal Cancer in Mice.pdf by Rongjie Zhang (5625083)

“…Here, we discovered that sodium tanshinone IIA sulfonate (STS), a sulfonate derived from tanshinone IIA (TSN), reduced the enzymatic activities of IDO1 and TDO2 with a half inhibitory concentration (IC₅₀) of less than 10 μM using enzymatic assays for natural product screening. …”

Data_Sheet_1_Impact of Prolonged COVID-19 Lockdown on Body Mass Index, Eating Habits, and Physical Activity of University Students in Bangladesh: A Web-Based Cross-Sectional Study.... by Md. Jamal Hossain (8697996)

“…The multinomial logistic regression analysis found a significant impact of gender [male vs. female: adjusted relative risk ratio (RRR) = 1.448; 95% confidence interval (CI) = 1.022, 2.053; p = 0.037], age (years) (<22 vs. >25: RRR =0.389, 95% CI = 0.213,0.710; p = 0.002, and 22–25 vs. >25: RRR = 0.473, 95% CI = 0.290, 0.772; p = 0.003), monthly family income (BDT) (<25,000 vs. >50,000: RRR = 0.525, 95% CI = 0.334,0.826; p = 0.005), university type (public vs. private: RRR = 0.540, 95% CI = 0.369, 0.791; p = 0.002), eating larger meals/snacks (increased vs. unchanged: RRR = 2.401, 95% CI = 1.597, 3.610; p < 0.001 and decreased vs. unchanged: RRR = 1.893, 95% CI = 1.218, 2.942; p = 0.005), and verbally or physically abuse (yes vs. no: RRR = 1.438, 95% CI = 0.977, 2.116; p = 0.066) on obesity during COVID-19 pandemic. …”

Theta oscillations (3.0–5.6 Hz) development of parameters C and L, average connectivity, and average power. by Dirk J. A. Smit (109730)

“…L and SL additionally showed an increase between ∼30 and ∼50 yrs, and a subsequent decrease to 55+.</p>…”

Data_Sheet_1_Biochemical analyses of a novel acidophilic GH5 β-mannanase from Trichoderma asperellum ND-1 and its application in mannooligosaccharides production from galactomannan... by Fengzhen Zheng (6084443)

“…Furthermore, TaMan5 displayed remarkable tolerance to acidic environments, retaining over 80% of its original activity at pH 3.0–5.0. The activity of TaMan5 was remarkably decreased by Cu²⁺, Mn²⁺, and SDS, while Fe²⁺/Fe³⁺ improved the enzyme activity. …”

Data_Sheet_1_Diabetes-specific formula with standard of care improves glycemic control, body composition, and cardiometabolic risk factors in overweight and obese adults with type... by Siew Ling Tey (7480985)

“…This randomized controlled trial investigated the effects of a diabetes-specific formula (DSF) on glycemic control and cardiometabolic risk factors in adults with type 2 diabetes (T2D).…”

DataSheet_1_A Novel Glucocorticoid and Androgen Receptor Modulator Reduces Viral Entry and Innate Immune Inflammatory Responses in the Syrian Hamster Model of SARS-CoV-2 Infection.... by Savannah M. Rocha (10826524)

“…Results indicated that oral administration of PT150 caused a dose-dependent decrease in replication of SARS-CoV-2 in lung, as well as in expression of ACE2 and TMPRSS2. …”

Table 1_Does screening mode matter? A repeated cross-sectional study of computer self-administered vs. clinician-administered screening of youth substance use in pediatric primary... by Chloe Gao (11107228)

“…</p>Results<p>Data represented 201,134 screening responses among N = 130,688 patients. Patients were 50.9% female; 31.3% were from the Northeast, 6.7% from the Midwest, 52.7% from the South, and 9.4% from the West. …”

Visual Stop-signal task (VSST): Participants responded to the direction of a central green arrow (“Go-stimulus”), and withheld their response when the arrow turned red (“Stop-stimu... by Kyriaki Nikolaou (462838)

“…In the classic variant, the SOA increased or decreased by 50msec as a function of whether participants were correct or not, respectively, at inhibiting their response to the “Stop-stimulus”. …”

Cortical Resonance Frequencies Emerge from Network Size and Connectivity by Caroline A. Lea-Carnall (2512003)

Data_Sheet_1_Modified tarsorrhaphy versus gold weight implant technique for paralytic lagophthalmos treatment in patients with leprosy: One-year observation of a randomized control... by Yunia Irawati (13272546)

“…Corneal sensitivity change in the inferior quadrant of the MT group (50.00 to 51.30 mm) and in the GWI group (49.61 to 52.93 mm) resulted in a p > 0.05. …”

DataSheet1_Physiologically-based pharmacokinetic modeling for single and multiple dosing regimens of ceftriaxone in healthy and chronic kidney disease populations: a tool for model... by Fawaz Alasmari (6517949)

“…</p><p>Results: The developed PBPK model was able to precisely describe the pharmacokinetic behavior of ceftriaxone in adult healthy population and in mild, moderate, and severe CKD patient populations. Decreasing the dose by approximately 25% in mild and 50% in moderate to severe renal disease provided a comparable exposure to the healthy population. …”

Data_Sheet_2_Modified tarsorrhaphy versus gold weight implant technique for paralytic lagophthalmos treatment in patients with leprosy: One-year observation of a randomized control... by Yunia Irawati (13272546)

“…Corneal sensitivity change in the inferior quadrant of the MT group (50.00 to 51.30 mm) and in the GWI group (49.61 to 52.93 mm) resulted in a p > 0.05. …”

Functional annotation of the rs2107595 region in HEK293T, A7r5, and HCASMCs. *p<0.05, ** p< 0.01, ***p<0.001, ****p<0.0001. by Sylvia T. Nurnberg (5663650)

“…The averaged results shows preferential pull-down of the minor (A, risk) allele of rs2107595. The dashed line marks the 50 percent allelic balance. …”

Data_Sheet_1_Spatial and Temporal Trends in HIV/AIDS Burden Among Worldwide Regions From 1990 to 2019: A Secondary Analysis of the Global Burden of Disease Study 2019.docx by Huan He (548057)

“…Purpose<p>HIV/AIDS is a critical public health concern worldwide. This article investigated the spatial and temporal trends in HIV/AIDS burden from 1990 to 2019.…”

datasheet1_Antihypertensive Effect of a Novel Angiotensin II Receptor Blocker Fluorophenyl Benzimidazole: Contribution of cGMP, Voltage-dependent Calcium Channels, and BKCa Channel... by Hina Iqbal (10496588)

“…</p><p>Results: FPD significantly decreased blood pressure in SHR. It relaxed superior mesenteric arteries in a concentration-dependent manner and significantly inhibited angiotensin II-induced contraction. …”

DataSheet_1_Acetate Promotes a Differential Energy Metabolic Response in Human HCT 116 and COLO 205 Colon Cancer Cells Impacting Cancer Cell Growth and Invasiveness.pdf by Sara Rodríguez-Enríquez (4373332)

“…In COLO 205, acetate (+glucose) increased the cell density (50%), mitochondrial protein content (3–10 times), 2-OGDH acetylation, and oxidative phosphorylation (OxPhos) flux (36%), whereas glycolysis remained unchanged vs. glucose-cultured cells; the acetate-induced OxPhos activation correlated with a high AcK activity, content, and acetylation (1.5–6-fold). …”