Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

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Primary endpoint analysis, i.e., time to first occurrence of combined event of 50% decrease in eGFR or ESRD. by Rozita Mohd (7411322)

Predictions of random forests (RF), gradient boosting machines (GBM), and neural networks (NN) trained on 12 covariates chosen using subjective feature selection. by Dennis Ochola (11626912)

Predictions of random forests (RF), gradient boosting machines (GBM), and neural networks (NN) trained on 17 covariates selected after recursive feature selection. by Dennis Ochola (11626912)

NN analysis to assign the importance of variables. by Sulmaz Ghahramani (3387635)

Apicoplast inhibitors decrease global parasite prenylation in the second IDC after treatment. by Kit Kennedy (4915510)

Mean plasma concentration-time profiles of paeoniflorin and paeonol after single oral administration in NC and DNBS-induced colitis rats. by Jin-Hwa Kim (101817)

Affinity analysis results (with a confidence level above 50%). by Marta R. Jabłońska (8491404)

Association of chemotherapy cycles and nausea and vomiting with the decrease of post-treatment vitamin D concentration (n = 136). by Herindita Puspitaningtyas (11618232)

Detection of the Challenging mutations at 1% VAF and 50 ng DNA input. by Lizhi Yu (12476136)

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Human cerebral organoids treated with VPA show a decreased size, impaired neurogenesis, and induction of senescence in NE cells. by Muriel Rhinn (406515)

Decreasing oxygen saturation with corresponding levels of NLR and D-dimer for understanding the interplay of inflammation. by Narendran Gopalan (110148)

Deep crypt secretory (DCS) cells are predominantly distributed in the proximal colon, with a progressive decrease towards the distal colon. by Daisuke Sugahara (2047696)

EGFR/ERK signaling activity decreases throughout LEC elimination with endocytic activity dependency. by Kevin Yuswan (19845885)

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(C)</b> Total cholesterol quantification (with fluorometric assay kit) in NIH3T3 cells depleted with sterols for 2 h or exposed to different CO₂ levels for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, **<i>P</i> < 0.01, nonsignificant (ns), two-sided Student’s <i>t</i> test). <b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …”

Treatment with TDF decreased cell viability and induced morphological changes in hepatic stellate cells. by Sung Won Lee (222509)

Conditional ablation of <i>Ybx1</i> leads to a reduction in cortical progenitor cell pool and a decrease in cortical thickness. by Jian Zhang (1682)

Thermal denaturation of ZIKV NS2B/NS3^pro and CHIKV nsP2^pro using fluorescence spectroscopy. by Raphael J. Eberle (9286932)

Reference mutations versus background noise across replicates. by Lizhi Yu (12476136)

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Analytical sensitivity and reproducibility. by Lizhi Yu (12476136)

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