Mode of action of the antimicrobial peptide Mel4 is independent of <i>Staphylococcus aureus</i> cell membrane permeability by Muhammad Yasir (3555896)

“…<div><p>Mel4 is a novel cationic peptide with potent activity against Gram-positive bacteria. …”

Data_Sheet_1_Dynamic Changes and Prognostic Value of Gut Microbiota-Dependent Trimethylamine-N-Oxide in Acute Ischemic Stroke.doc by Chuhong Tan (6292904)

“…</p><p>Results: TMAO levels showed no significant changes before and within 24 h of AIS treatment (at admission) but decreased significantly thereafter. Elevated log₂-transformed baseline TMAO levels were associated with increased risks of 90-day [odds ratio (OR), 2.62; 95% confidence interval (CI), 1.55–4.45; p < 0.001] and 12-month (OR, 3.59; 95% CI, 2.12–6.09; p < 0.001) major ischemic events, as well as 90-day (OR, 2.89; 95% CI, 1.46–5.71; p = 0.002) and 12-month (OR, 2.58; 95% CI, 1.50–4.46; p = 0.001) unfavorable functional outcomes, after adjustments for confounding factors. …”

Image_1_Safety and Immunological Evaluation of Interleukin-21 Plus Anti-α4β7 mAb Combination Therapy in Rhesus Macaques.jpg by Maria Pino (109981)

“…<p>Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections compromise gut immunological barriers, inducing high levels of inflammation and a severe depletion of intestinal CD4⁺ T cells. …”

Table_1_Safety and Immunological Evaluation of Interleukin-21 Plus Anti-α4β7 mAb Combination Therapy in Rhesus Macaques.docx by Maria Pino (109981)

“…<p>Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections compromise gut immunological barriers, inducing high levels of inflammation and a severe depletion of intestinal CD4⁺ T cells. …”

Table_2_Safety and Immunological Evaluation of Interleukin-21 Plus Anti-α4β7 mAb Combination Therapy in Rhesus Macaques.docx by Maria Pino (109981)

“…<p>Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections compromise gut immunological barriers, inducing high levels of inflammation and a severe depletion of intestinal CD4⁺ T cells. …”

“Age matters”—German claims data indicate disparities in lung cancer care between elderly and young patients by Julia Walter (3321750)

“…</p><p>Results</p><p>Compared with the reference group “non-elderly”, the likelihood of receiving any tumor-directed treatment was significantly lower in all age groups with a decreasing gradient with advancing age. Elderly lung cancer patients received significantly fewer resections and radiotherapy than non-elderly patients. …”

Image_2_Safety and Immunological Evaluation of Interleukin-21 Plus Anti-α4β7 mAb Combination Therapy in Rhesus Macaques.jpg by Maria Pino (109981)

“…<p>Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections compromise gut immunological barriers, inducing high levels of inflammation and a severe depletion of intestinal CD4⁺ T cells. …”

Table 2_Isoenergetic reduction of dietary macronutrients affects body composition, physical activity, and post-prandial hormone responses in lean and obese cats fed to maintain bod... by Hannah Godfrey (12256593)

“…Introduction<p>High consumption of dietary carbohydrates (nitrogen-free extract, NFE) in extruded dry foods is postulated as a risk factor for feline obesity, though evidence is limited. …”

Gcn4 occupancy changes in CR mutants. by Yashpal Rawal (606804)

“…For these and all subsequent box plots, each box depicts the interquartile range containing 50% of the data, intersected by the median; the notch indicates a 95% confidence interval (CI) around the median, and <i>p</i> values for the significance of differences in median values calculated by the Mann-Whitney-Wilcoxon test are indicated as follows: ****, ≤ 0.0001; ***, ≤ 0.001; **, ≤ 0.01; *, ≤ 0.05; ns, > 0.05. …”

Table 1_Isoenergetic reduction of dietary macronutrients affects body composition, physical activity, and post-prandial hormone responses in lean and obese cats fed to maintain bod... by Hannah Godfrey (12256593)

“…Introduction<p>High consumption of dietary carbohydrates (nitrogen-free extract, NFE) in extruded dry foods is postulated as a risk factor for feline obesity, though evidence is limited. …”

Image_1_Cellular and Humoral Immune Responses and Breakthrough Infections After Two Doses of BNT162b Vaccine in Healthcare Workers (HW) 180 Days After the Second Vaccine Dose.TIFF by Alessandra Mangia (626370)

“…Among COVID-naive, the impact of age, which was observed at earlier stages, disappeared at d180, while it remained significant for 81 who had experienced a previous infection. Following the predictive model of protection by Khoury, we transformed the neutralizing titers in IU/ml and used a 54 IU/ml threshold to identify subjects with 50% protective immunity. …”

Image_2_Cellular and Humoral Immune Responses and Breakthrough Infections After Two Doses of BNT162b Vaccine in Healthcare Workers (HW) 180 Days After the Second Vaccine Dose.TIFF by Alessandra Mangia (626370)

“…Among COVID-naive, the impact of age, which was observed at earlier stages, disappeared at d180, while it remained significant for 81 who had experienced a previous infection. Following the predictive model of protection by Khoury, we transformed the neutralizing titers in IU/ml and used a 54 IU/ml threshold to identify subjects with 50% protective immunity. …”

Image_1_Combined application of melatonin and Bacillus sp. strain IPR-4 ameliorates drought stress tolerance via hormonal, antioxidant, and physiomolecular signaling in soybean.jpe... by Odongkara Peter (18861397)

“…Likewise, Bacillus–melatonin-treated plants enhanced the uptake of magnesium, calcium, and potassium by 31.2%, 50.7%, and 30.5%, respectively. Under the same conditions, the salicylic acid content increased by 29.1%, whereas a decreasing abscisic acid content (25.5%) was observed. …”

DataSheet_1_Combined application of melatonin and Bacillus sp. strain IPR-4 ameliorates drought stress tolerance via hormonal, antioxidant, and physiomolecular signaling in soybean... by Odongkara Peter (18861397)

“…Likewise, Bacillus–melatonin-treated plants enhanced the uptake of magnesium, calcium, and potassium by 31.2%, 50.7%, and 30.5%, respectively. Under the same conditions, the salicylic acid content increased by 29.1%, whereas a decreasing abscisic acid content (25.5%) was observed. …”

Biochemical data. by Abdallah Tageldein Mansour (21158819)

“…The colitic group showed a significant increase (P < 0.05) in C-reactive protein (CRP) and myeloperoxidase (MPO) and nitric oxide (NO) (35.60, 163.30 and 280 nmol/g tissue respectively) and higher expression (P < 0.05) <i>IL-17</i>, <i>TNF-α</i>, and <i>IL-1β</i> (increased up to 2.99, 4.36 and 4.90 respectively unlike PPE-NPsIII that recorded reduced levels of CRP, MPO and NO (8,96, 78.30 and 123 nmol/g tissue respectively) and much lower (P < 0.05) levels of IL-17, TNF-α, and IL-1β expression (decreased to 1.23, 1.69 and 1.64, respectively). …”

Scoring of Disease Activity Index (DAI). by Abdallah Tageldein Mansour (21158819)

“…The colitic group showed a significant increase (P < 0.05) in C-reactive protein (CRP) and myeloperoxidase (MPO) and nitric oxide (NO) (35.60, 163.30 and 280 nmol/g tissue respectively) and higher expression (P < 0.05) <i>IL-17</i>, <i>TNF-α</i>, and <i>IL-1β</i> (increased up to 2.99, 4.36 and 4.90 respectively unlike PPE-NPsIII that recorded reduced levels of CRP, MPO and NO (8,96, 78.30 and 123 nmol/g tissue respectively) and much lower (P < 0.05) levels of IL-17, TNF-α, and IL-1β expression (decreased to 1.23, 1.69 and 1.64, respectively). …”

Primers sequences used in this study. by Abdallah Tageldein Mansour (21158819)

“…The colitic group showed a significant increase (P < 0.05) in C-reactive protein (CRP) and myeloperoxidase (MPO) and nitric oxide (NO) (35.60, 163.30 and 280 nmol/g tissue respectively) and higher expression (P < 0.05) <i>IL-17</i>, <i>TNF-α</i>, and <i>IL-1β</i> (increased up to 2.99, 4.36 and 4.90 respectively unlike PPE-NPsIII that recorded reduced levels of CRP, MPO and NO (8,96, 78.30 and 123 nmol/g tissue respectively) and much lower (P < 0.05) levels of IL-17, TNF-α, and IL-1β expression (decreased to 1.23, 1.69 and 1.64, respectively). …”

Data_Sheet_1_Prognostic Impact of Left Ventricular Ejection Fraction in Patients With Moderate Aortic Regurgitation: Potential Implications for Treatment Decision-Making.pdf by Qinghao Zhao (11182500)

“…Among patients with LVEF 35–55%, AVI within 6 months of diagnosis was associated with a reduced risk of death or HHF compared with medical treatment alone (adjusted HR: 0.15; 95% CI: 0.04–0.50; P = 0.002), whereas this benefit was markedly attenuated when LVEF was ≤35% (adjusted HR: 0.65; 95% CI: 0.21–1.97; P = 0.441, P-interaction = 0.010) or >55% (adjusted HR: 0.40; 95% CI: 0.14–1.15; P = 0.089, P-interaction = 0.723).…”

<i>uif</i> is positively regulated by <i>lov</i> in the tracheae and required for tracheal EP growth. by Fanli Zhou (3142398)

“…<p>A. Semi Q RT-PCR analysis of <i>uif</i> transcript levels in larvae with <i>lov</i> knockdown in the tracheae. …”

DataSheet_1_Metabolome and transcriptome association analysis revealed key factors involved in melatonin mediated cadmium-stress tolerance in cotton.docx by Ling Li (38566)

“…The results showed that the cotton seedlings were dwarfed and the leaves were wilted and yellow under Cd stress. The application of 50 µmol L⁻¹ MT significantly increased the superoxide dismutase (SOD) activity and malondialdehyde (MDA) content under Cd stress, but 100 µmol L⁻¹ MT significantly decreased SOD activity, while increased ascorbate peroxidase (APX) activity significantly. …”