Image_3_Guizhi Fuling capsule relieves memory deficits by inhibition of microglial neuroinflammation through blocking JAK2/STAT3 pathway in presenilin1/2 conditional double knockou... by Guang Yang (154978)

Image_1_Guizhi Fuling capsule relieves memory deficits by inhibition of microglial neuroinflammation through blocking JAK2/STAT3 pathway in presenilin1/2 conditional double knockou... by Guang Yang (154978)

P4HA3 deficiency increased sensitization to immune checkpoint inhibitors and P4HA3 could predict the clinical therapeutic effect of PD-1 inhibitor (Camrelizumab). by Hong Yan Huang (20135965)

“…<p>(A) P4HA3 deficiency inhibited migration and invasion abilities of MDA-MB-231, HCT116 and A549 cell lines by transwell assay. …”

Quantifying the contribution of individual currents to rate-dependent APD adaptation. by Young-Seon Lee (565899)

“…<p>AP shapes changed during the transition between 0.5 Hz to 2 Hz in control (A) and the PeAF condition (PeAF1) (B). …”

Propentofylline Prevents Sickness Behavior and Depressive-Like Behavior Induced by Lipopolysaccharide in Rats via Neuroinflammatory Pathway by Márcia M. T. Moraes (3618056)

“…Aware of the efficacy limits of existing antidepressant drugs and the potential anti-inflammatory properties of propentofylline, we sought to evaluate the use of propentofylline as a depression treatment. We used a rat model of depression induced by repetitive lipopolysaccharide (LPS) administrations. …”

ATO inhibits migration in HUVECs. by Hong-yan Ge (783538)

“…(Original magnification:×100). A: a: Control group 0 hour; b: ATO 5.0 umol/L group 0 hour; c: Control group 48 h; d: ATO 5.0 umol/L group 48 h. …”

Image 1_Uncovering the new landscape of leukoaraiosis through the circular RNA-miRNA-mRNA axis.jpeg by Canmin Zhu (22555766)

“…The apoptotic gene AIFM1 was identified as a downstream target of miR-145-5p.</p>Conclusion<p>circ-0018401 acts as a crucial biomarker in white matter injury by regulating the miR-145-5p/AIFM1 axis. …”

Monitoring of mouse rearing activity in the peanut allergy model. by Krisztina Manzano-Szalai (2560123)

“…<p>(A) Readout of vertical physical activity of individual mice. …”

<i>Celsr3|Emx1</i> mice display walking deficits after surgery. by Yuetong Ding (594520)

“…<p>The walking ability was evaluated using the Catwalk tests five months after surgery. In control mice (A), the footprints (right forelimb, RF and left hind limb, LH) were clearly identified. …”

Stat3 was involved in LPS induced chemokines protein expression. by Xiaodong Liu (403701)

“…LPS treatment for 6 hours led to up-regulation of at least 13 proteins including Il-1α (B3,4), Il-1β (B5,6), TNFa (D9,10), Cxcl1 (A3,4), Cxcl3 (A5,6), Cxcl (A7,8), Cx3cl1 (A11,12), Cxcl10 (C7,8), Cxcl5 (C9,10), Ccl3 (C15,16), Ccl20 (C17,18), Ccl5 (D3,4) and Timp1 (D7,8). siStat3 transfection reduced the effects of LPS, causing attenuated levels of Cxcl2, Cx3cl1, Cxcl10, Ccl3 and Timp1 compared to the siNeg transfected cells. …”

Measuring the Evolutionary Rewiring of Biological Networks by Chong Shou (233469)

Cyclin D1 regulates osteoarthritis chondrocyte apoptosis <i>via</i> WNT3/β-catenin signalling by Yi-Yue Chen (6790274)

“…</p> <p>Cyclin D1 was significantly decreased with OA grade (<i>p</i> < .05). After siCyclin D1 transfection, the expression level of WNT3 and nuclear β-catenin were significantly increased, while Wnt10a and total β-catenin were not obviously changed. …”

Supplementary Material for: Minimal Change Disease and Focal Segmental Glomerulosclerosis are associated with good kidney prognosis and Thrombotic Microangiopathy with poor kidney... by Neves P.D.M.M. (20408168)

“…The time between COVID-19 diagnosis and kidney biopsy was 30 (15-60) days. Most patients had decreased kidney function at diagnosis, 43.5% required dialysis upon diagnosis, 77.6% received immunosuppression, and 2/3 achieved a clinical remission. …”

Fragments 1 and 2 differ in the nature of the allosteric effect in Hsp90. by Arun Chandramohan (2813848)

“…<p><b>(A)</b> The absolute difference in numbers of deuterons (inferred from difference in mass in Daltons (Da) (y-axis) between the free and ligand bound state is plotted for each pepsin digest fragment listed from the N to C terminus (x-axis) of Hsp90 for each deuterium exchange time point (t = 0.5, 2, 5, 10 min) in a ‘difference plot’. …”

File name: Nicholson_et_al_Dataset_2_ESM.xlsx Title: Dataset 2Description: Calculations for palaeo-non-marine area at 15 degree palaeolatitudinal bands for Jurassic, Lower Cretaceo... by David B. Nicholson (638352)

Supplementary Material for: Cystic Gene Dosage Influences Kidney Lesions After Nephron Reduction by Le Corre S. (3683830)

Heterogeneous development of β-cell populations in diabetes-resistant and susceptible mice by Pascal Gottmann (5339213)

File name: Nicholson_et_al_Mesozoic_latitude_script_ESM.R Title: Mesozoic turtle latitude analyses R scriptDescription: R script for cleaning and partitioning Mesozoic turtle occur... by David B. Nicholson (638352)

Supplementary Material for: Induction of Myeloid-Derived Suppressor Cells in Cryopyrin-Associated Periodic Syndromes by Ballbach M. (2855015)

Paper_Bergamasco_et_al_B by MuscuLab UFSCar (20622404)

“…Given the role of ERα in satellite cell (SC) regulation, we also examined fiber type-specific SC content and SC-related proteins (MyoD, myogenin [Myog], cyclin D1 [CycD1]). …”