A Novel Highly Potent Autotaxin/ENPP2 Inhibitor Produces Prolonged Decreases in Plasma Lysophosphatidic Acid Formation <i>In Vivo</i> and Regulates Urethral Tension by Hiroshi Saga (584103)

“…In this study, we report the discovery of a highly potent autotaxin/ENPP2 inhibitor, ONO-8430506, which decreased plasma lysophosphatidic acid formation.…”

Means and standard deviations for Known condition. by Mengnan Wu (769253)

GluN2A(D731N) decreases channel open probability. by Kai Gao (120150)

“…The di-heteromeric mutant (2A-D731N) and tri-heteromeric receptors with two-copies of the mutant subunit (D731N/D731N) showed a prolonged inhibition rate, reflecting a decreased channel open probability. …”

Down-regulation of PDCD4 attenuates the ability of resveratrol to decrease viability and invasiveness of PC-3M-MM2 cells. by Sandeep Sheth (112040)

Effects of High-Intensity Interval Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ul... by Othmar Moser (789838)

“…Before exercise, standardized meals were administered, and short-acting insulin dose was reduced by 25% (A), 50% (B), and 75% (C) dependent on mean exercise intensity. …”

Boxplots comparing KGE_mean values of every scenario group (a-e) for calibration, where the black star is showing the mean. by Fabian Mitze (21084251)

Mean TOC concentration and mean bacterioplankton abundance for Santa Barbara Channel phytoplankton-DOC experiments. by Anna K. James (3812875)

Decreased phagocytosis of <i>Y. pestis</i> in bone marrow derived macrophages (BMMs) and neutrophils (BMNs) from <i>Irf3^−/−</i> mice. by Ami A. Patel (149580)

Porcupine plots of the PCA analysis depicting the movement and altitude of the C-alpha atoms throughout the 50 ns simulation in the native and mutant complexes. by Sneha P. (3926957)

Mean offspring production of the aphid population treated with different fungal isolates at a concentration of 3.2×10⁶. by Aime Cheoh Enoh (20141758)

<i>P. brasiliensis</i>-infected mice treated with CFA present remarkable decrease of fungal burden and increase of cytokines production. by Leandro Licursi de Oliveira (374413)

Silencing class II PI3Ks decreases autophagy in both control and <i>Vps34</i> null MEFs. by Kelly Devereaux (466106)

ATRA decreases mRNA expression of HO-1, GCLM and x-CT and lowers GSH level in BTZ-treated cells. by A. L. Furfaro (2587792)

Over-expression of DN VPS4 in HEK293T cells leads to increased extracellular α-synuclein and parallel decrease in lysosome. by Takafumi Hasegawa (18204)

“…Treatment with lysosomal inhibitor bafilomycin A1 (0–10 nM) for 24 hours induced the buildup of cellular αSYN oligomers (<i>asterisk</i>) in parallel with the increase of extracellular αSYN monomer (<i>closed triangle</i>). …”

Percentage of living PC3 cells in the presence of different concentrations of CS-C (0–3.3 nM). by Célia Dos Santos (306471)

Estimated mean lichen species richness vs. distance to the DMTS haul road in Cape Krusenstern National Monument, Alaska, on a log-log scale from a Bayesian posterior predictions mo... by Peter N. Neitlich (4034300)

Blocking K_Ca3.1 channels decreases TGFβ1-dependent myofibroblast collagen secretion. by Katy Morgan Roach (504094)

Relationship between weighted-mean effect sizes and the weighted-mean percent road-kill decrease for crossing structures and fencing alone and in combination. by Trina Rytwinski (568200)

The percent of students who, if a science instructor were to tell a joke about a specific subject, might find the joke funny and might find the joke offensive. by Katelyn M. Cooper (5634851)

Alterations in fat body Lsd1 and Lsd2 levels upon the genetic increase or decrease in cardiac Snail TF levels. by Ying Liu (18461)