Showing 11,781 - 11,800 results of 67,179 for search '(( 10 ((nm decrease) OR (mean decrease)) ) OR ( 50 ((nn decrease) OR (a decrease)) ))', query time: 1.16s Refine Results
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    Synthesis and Biological Evaluation of Heterocyclic Ring-Fused 20(<i>S</i>)‑Protopanaxadiol Derivatives as Potent Antiosteoporosis Agents by Shuan-Jing Wang (16854232)

    Published 2023
    “…Among these compounds, <b>33</b> (SH491, IC<sub>50</sub> = 11.8 nM) showed the highest potency with 100% inhibition at 0.1 μM and 44.4% inhibition at an even lower concentration of 0.01 μM, which was much more potent than the lead compound PPD (IC<sub>50</sub> = 10.3 μM). …”
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    Berberine inhibits 4-AP-induced glutamate release from rat cerebrocortical nerve terminals; this effect is due to a decrease in vesicular exocytosis. by Tzu-Yu Lin (423761)

    Published 2013
    “…Ca<sup>2+</sup>-independent release was assayed by omitting CaCl<sub>2</sub> and adding 300 µM EGTA 10 min prior to depolarization. B: Dose-response curves of decrease in 4-AP-evoked glutamate release in the presence of berberine. …”
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