Synthesis and Biological Evaluation of New Chalcogen Semicarbazone (<i>S</i>, <i>Se</i>) and Their Azole Derivatives against Chagas Disease by Mercedes Rubio-Hernández (20036142)

“…Three compounds were selected, based on their activity against the intracellular amastigotes (EC₅₀ < 1 μM, SI > 10) and cruzain (IC₅₀ < 100 nM, SI > 5.55) which compared favorably with the approved drug, Benznidazole, and the well-established cruzain inhibitor K777. …”

Synthesis and Biological Evaluation of New Chalcogen Semicarbazone (<i>S</i>, <i>Se</i>) and Their Azole Derivatives against Chagas Disease by Mercedes Rubio-Hernández (20036142)

“…Three compounds were selected, based on their activity against the intracellular amastigotes (EC₅₀ < 1 μM, SI > 10) and cruzain (IC₅₀ < 100 nM, SI > 5.55) which compared favorably with the approved drug, Benznidazole, and the well-established cruzain inhibitor K777. …”

Fig 1 - by Naoya Ishibashi (18722999)

Typical examples of cystometry charts on NS+Sham, AcOH+Sham, and AcOH+Laser group. by Naoya Ishibashi (18722999)

S1 Data - by Naoya Ishibashi (18722999)

Effects of inserting AOP/LexA transgenes into <i>attP40</i> on nuclear clustering severity. by Kevin van der Graaf (14259532)

The small blue circles show the IC-volume (mean of left and right) from 72 males and the small red squares from 51 females as a function of age. by Pingling Kwok (14896191)

Changes in baseline T-cell activation markers through week 12 and week 24 according to the linear regression model. a. by Tosi M. Mwakyandile (16408705)

The effects of ASP on recombinant nectin-2. by Hidetomo Kobayashi (535837)

Oxytocin decreases locally evoked CeA GABAergic signaling and blunts alcohol effects. by Brendan J. Tunstall (6593357)

Schematic representation of the structure of the substrate in the model. by Eric Behle (11426692)

Levels of Stt7 Decrease under Prolonged State 1 Conditions and High Light by Sylvain Lemeille (7986)

Reducing neuronal HS sulfation increases mCWD solubility and decreases fibril length. by Patricia Aguilar-Calvo (532439)

Taurocholate significantly decreases toxin B-mediated Caco-2 cell membrane integrity. by Charles Darkoh (482779)

Dr. Hannah Lapp’s—like custom features in action. by Piotr Popik (292215)

DAPIT over-expression decreased mitochondrial mass and mtDNA content in DAPIT cells. by Heidi Kontro (768437)

The levels of antitoxin and toxin-antitoxin complexes decrease with increasing number of operator binding sites. by Lendert Gelens (451747)

Ovariectomy (OVX) induced decrease in hexokinase expression and activity: prevention by 17β-estradiol. by Fan Ding (302565)

Geometric mean concentrations of 5 most abundant PCDD/F congeners and the sum of other congeners (A), and PCDD and PCDF TEQ (C) in different study areas during the first (1972–1986... by Matti Viluksela (321291)

Decrease in optical density of <i>gerP</i> mutants in L-alanine and inosine. by Katherine A. Carr (259428)