Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…[(η⁶-bip)Os(en)Cl]PF₆/BF₄ (<b>1PF</b><b>₆</b>/<b>BF</b><b>₄</b>) and [(η⁶-THA)Os(en)Cl]BF₄ (<b>2BF</b><b>₄</b>) were cytotoxic toward both the human A549 lung and A2780 ovarian cancer cell lines, with IC₅₀ values of 6−10 μM, comparable to the anticancer drug carboplatin. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…[(η⁶-bip)Os(en)Cl]PF₆/BF₄ (<b>1PF</b><b>₆</b>/<b>BF</b><b>₄</b>) and [(η⁶-THA)Os(en)Cl]BF₄ (<b>2BF</b><b>₄</b>) were cytotoxic toward both the human A549 lung and A2780 ovarian cancer cell lines, with IC₅₀ values of 6−10 μM, comparable to the anticancer drug carboplatin. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…[(η⁶-bip)Os(en)Cl]PF₆/BF₄ (<b>1PF</b><b>₆</b>/<b>BF</b><b>₄</b>) and [(η⁶-THA)Os(en)Cl]BF₄ (<b>2BF</b><b>₄</b>) were cytotoxic toward both the human A549 lung and A2780 ovarian cancer cell lines, with IC₅₀ values of 6−10 μM, comparable to the anticancer drug carboplatin. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…[(η⁶-bip)Os(en)Cl]PF₆/BF₄ (<b>1PF</b><b>₆</b>/<b>BF</b><b>₄</b>) and [(η⁶-THA)Os(en)Cl]BF₄ (<b>2BF</b><b>₄</b>) were cytotoxic toward both the human A549 lung and A2780 ovarian cancer cell lines, with IC₅₀ values of 6−10 μM, comparable to the anticancer drug carboplatin. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…[(η⁶-bip)Os(en)Cl]PF₆/BF₄ (<b>1PF</b><b>₆</b>/<b>BF</b><b>₄</b>) and [(η⁶-THA)Os(en)Cl]BF₄ (<b>2BF</b><b>₄</b>) were cytotoxic toward both the human A549 lung and A2780 ovarian cancer cell lines, with IC₅₀ values of 6−10 μM, comparable to the anticancer drug carboplatin. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…[(η⁶-bip)Os(en)Cl]PF₆/BF₄ (<b>1PF</b><b>₆</b>/<b>BF</b><b>₄</b>) and [(η⁶-THA)Os(en)Cl]BF₄ (<b>2BF</b><b>₄</b>) were cytotoxic toward both the human A549 lung and A2780 ovarian cancer cell lines, with IC₅₀ values of 6−10 μM, comparable to the anticancer drug carboplatin. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…[(η⁶-bip)Os(en)Cl]PF₆/BF₄ (<b>1PF</b><b>₆</b>/<b>BF</b><b>₄</b>) and [(η⁶-THA)Os(en)Cl]BF₄ (<b>2BF</b><b>₄</b>) were cytotoxic toward both the human A549 lung and A2780 ovarian cancer cell lines, with IC₅₀ values of 6−10 μM, comparable to the anticancer drug carboplatin. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…[(η⁶-bip)Os(en)Cl]PF₆/BF₄ (<b>1PF</b><b>₆</b>/<b>BF</b><b>₄</b>) and [(η⁶-THA)Os(en)Cl]BF₄ (<b>2BF</b><b>₄</b>) were cytotoxic toward both the human A549 lung and A2780 ovarian cancer cell lines, with IC₅₀ values of 6−10 μM, comparable to the anticancer drug carboplatin. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…[(η⁶-bip)Os(en)Cl]PF₆/BF₄ (<b>1PF</b><b>₆</b>/<b>BF</b><b>₄</b>) and [(η⁶-THA)Os(en)Cl]BF₄ (<b>2BF</b><b>₄</b>) were cytotoxic toward both the human A549 lung and A2780 ovarian cancer cell lines, with IC₅₀ values of 6−10 μM, comparable to the anticancer drug carboplatin. …”

Map of the study area, representing the 50 provinces, divided between the 6 different regions. by Jacopo Cerri (6271958)

Substitution of a lysine residue at position 8 of two model 9mer H2-K^b epitope precursors leads to a marked decrease of N-terminus trimming by ERAP1 <i>in vitro</i>. by Irini Evnouchidou (375919)

“…<p><i>Panels </i><i>A</i><i> and </i><i>B</i>, peptides LSIINFEKL and the variant LSIINFEAL (both at 50 µM) were incubated with 7.8 nM of ERAP1 for 1 hr at 37°C and the products analyzed by RP-HPLC. …”

Selective Inhibitors of Janus Kinase 3 Modify Responses to Lipopolysaccharides by Increasing the Interleukin-10-to-Tumor Necrosis Factor α Ratio by Julian Laux (13047767)

“…JAK1 is required for IL-10 receptor signaling, which suggests that, at exposure above the IC₅₀ (55 nM for tofacitinib on JAK1), there is less feedback control of TNFα levels. …”

Chronic, sublethal neonicotinoid exposure decreases cumulative weight gain and cluster size of honey bee colonies. by Sarah C. Wood (4730634)

Cardiac Contractility Structure-Activity Relationship and Ligand-Receptor Interactions; the Discovery Of Unique and Novel Molecular Switches in Myosuppressin Signaling by Megan Leander (459603)

“…Further, these motifs were present in red flour beetle, common water flea, honey bee, domestic silkworm, and termite MS-Rs. RhpMS and DrmMS decreased <i>R</i>. <i>prolixus</i> cardiac contractility dose dependently with EC₅₀ values of 140 nM and 50 nM. …”

The loss of Sad kinases leads to a decrease in the number of neuronal progenitors in the cortex. by Pratibha Dhumale (5146484)

Hepcidin quantification by WCX-TOF MS in human samples that were pre-incubated with 0, 5 or 10 nM of PRS-080 to block binding of hepcidin to the WCX beads. by Coby M. M. Laarakkers (228091)

Variation in the energy fluxes per CS and the density of RCs of leaves of Baijinpao and Kangnaixin under Al stress. by Jing Zhang (23775)

Prorocentin-5: A Cytotoxic Polyketide from the Benthic Marine Dinoflagellate <i>Prorocentrum lima</i> by Yunseok Choi (5625245)

Subjects:

The detection of red (652–669 nm) and green (533–550 nm) fluorescence from yellow-green and violet laser excitation in control and H₂O₂-treated <i>M</i>. <i>a... by Emma T. Brentjens (17295999)

Stable Silencing of <i>MAGE-C1/CT7</i> expression in myeloma cell line SKO-007 transduced with pRS-shRNA-<i>MAGE-C1/CT7</i> also leads to cell cycle changes when treated with 10 nM... by Fabricio de Carvalho (195896)

“…In G2/M phase, bortezomib-treated and inhibited cells had lower percentage (48%) of PI stained cells when compared with control cells (empty vector [13%] and ineffective shRNA [9%]) [10 nM bortezomib by 48 h] (**p<0.01). The number of dead cells (Sub-G1) was higher in bortezomib-treated and inhibited (shRNA-<i>MAGE-C1/CT7</i>) cells when compared with controls (empty vector and ineffective shRNA), but this difference was not statistically significant. …”