Shape-Based Reprofiling of FDA-Approved Drugs for the H₁ Histamine Receptor by Sridhar R. Vasudevan (589877)

“…Reprofiling of existing drugs to treat conditions not originally targeted is an attractive means of addressing the problem of a decreasing stream of approved drugs. …”

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

Subjects:

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

Subjects:

Dynamic Regulation of Proton and Water Transport through an Acylhydrazone-Based Photoresponsive Channel by Paras Wanjari (22259362)

“…Upon irradiation at 310 nm, all derivatives showed increased proton transport rates, which subsequently decreased after exposure to 365 nm, confirming the photoresponsive behavior of the system. …”

The effect of glibenclamide on channel activity at +20, 0 and -20 mV. by Sajjad Salari (736104)

“…Histogram bars show current amplitudes and P_o of reconstituted channels in absence or presence of glibenclamide. The addition of 50 μM glibenclamide resulted in a decreased current jump amplitude and a reduction in P_o. 100 μM glibenclamide caused a total channel inhibition at +20 and 0 mV (n = 5), but was ineffective at -20 mV. …”

Tendency chart of monthly FVC mean. by Yichuan Zhang (2888345)

“…The dynamic changes of monthly FVC at regional scale were described through the dynamic changes in the monthly FVC mean and in the FVC areas at various scales, and the dynamic changes in the monthly FVC were analyzed using the coefficient of variation and curve change trends. …”

Assessment of the organ weights and lung pathology of rats exposed to either OIR, 670nm or both. by Riccardo Natoli (443560)

670 nm light treatment reduces mean clinical score and signs of MOG-induced EAE. by Kamaldeen A. Muili (297505)

“…(<b>D</b>) Mice were treated with 670 nm light (-□-; n = 10) or no light (restraint stress; -▪-; n = 7) using the double-treatment protocol. …”

Regional contemporary (1990–1999 mean) precipitation and JULES inundation fraction over the Amazon basin. by Nic Gedney (19762301)

Bumblebees were subjected to 5 day exposure to Imidacloprid and/or/none twice daily 670 nm. by Michael Barry Powner (11337243)

Intensity-modulated proton therapy decreases dose to organs at risk in low-grade glioma patients: results of a multicentric <i>in silico</i> ROCOCO trial by Daniëlle B. P. Eekers (5560430)

Maximal aortic contraction or relaxation, logEC50 and area under the curve (AUC) following 12 weeks of voluntary wheel running or no voluntary wheel running in nephrectomy and cont... by Cecilia M. Shing (709027)

Arm tremor and rigidity during settings (mean ± sd). by Verneri Ruonala (12419145)

Calcineurin acts as a Ca²⁺ sensor for metamodulation of LP I_h in 5nM DA. by Wulf-Dieter C. Krenz (693267)

“…Black asterisks indicate that a one-way ANOVA on the four DA-treatment groups with Tukey’s post hoc tests that made all pair wise comparisons showed that the decrease observed for the TTX + DA + (+50 OSC) treatment group was significantly different from the other three DA treatment groups, and that those three DA treatment groups [(TTX+DA, TTX+DA+FK506, TTX+DA+FK506+(+50 OSC)] were not significantly different from one another: (F (3,26) = 11.08; p = 0.0001). …”

B-THP-Ts decrease cellular ATP levels. by Lindsay B. Tulloch (1266861)

Temperature changes (mean values ± standard deviation) during NES-beef chilling with the slow (SM), accelerated (AM), and fast (FM) methods. by Joanna Katarzyna Banach (10023737)

Effect of control or Notch3 ASOs on <i>Notch3</i> mRNA expression and cell replication in calvarial osteoblast-enriched cells. by Ernesto Canalis (516050)

Macrophage-secreted factors decrease RBP4 production. by Primoz Kotnik (382835)

Super-Resolution Luminescence Microspectroscopy Reveals the Mechanism of Photoinduced Degradation in CH₃NH₃PbI₃ Perovskite Nanocrystals by Aboma Merdasa (1367232)

Super-Resolution Luminescence Microspectroscopy Reveals the Mechanism of Photoinduced Degradation in CH₃NH₃PbI₃ Perovskite Nanocrystals by Aboma Merdasa (1367232)