GluN2A(D731N) decreases channel open probability. by Kai Gao (120150)

“…The di-heteromeric mutant (2A-D731N) and tri-heteromeric receptors with two-copies of the mutant subunit (D731N/D731N) showed a prolonged inhibition rate, reflecting a decreased channel open probability. …”

Porcupine plots of the PCA analysis depicting the movement and altitude of the C-alpha atoms throughout the 50 ns simulation in the native and mutant complexes. by Sneha P. (3926957)

Median ATR-FTIR absorbance spectra of malignant (<i>n = 88</i>) and benign (<i>n = 78</i>) breast tissue samples. by Rock Christian Tomas (12003669)

The percent of students who, if a science instructor were to tell a joke about a specific subject, might find the joke funny and might find the joke offensive. by Katelyn M. Cooper (5634851)

Design, Synthesis, and Biological Evaluation of Indoline and Indole Derivatives as Potent and Selective α_1A-Adrenoceptor Antagonists by Fei Zhao (183673)

“…In this study, two highly selective and potent α_1A-AR antagonists, compounds (<i>R</i>)-<b>14r</b> (IC₅₀ = 2.7 nM, α_1B/α_1A = 640.1, α_1D/α_1A = 408.2) and (<i>R</i>)-<b>23l</b> (IC₅₀ = 1.9 nM, α_1B/α_1A = 1506, α_1D/α_1A = 249.6), which exhibited similar activities and better selectivities in cell-based calcium assays as compared with the marketed drug silodosin (IC₅₀ = 1.9 nM, α_1B/α_1A = 285.9, α_1D/α_1A = 14.4), were identified. …”

Silencing class II PI3Ks decreases autophagy in both control and <i>Vps34</i> null MEFs. by Kelly Devereaux (466106)

Over-expression of DN VPS4 in HEK293T cells leads to increased extracellular α-synuclein and parallel decrease in lysosome. by Takafumi Hasegawa (18204)

“…Treatment with lysosomal inhibitor bafilomycin A1 (0–10 nM) for 24 hours induced the buildup of cellular αSYN oligomers (<i>asterisk</i>) in parallel with the increase of extracellular αSYN monomer (<i>closed triangle</i>). …”

Plant growth, nodulation, and N content as affected by manipulating of GmNN1/FT2a. by Xinxin Li (281237)

Expression of <i>GmNN1/FT2a</i> in various tissues of soybean plants. by Xinxin Li (281237)

GmNN1/FT2a interacted with GmNYFA-C in the BiFC assay. by Xinxin Li (281237)

SS-31 treatment reduced ox-LDL-induced lipid accumulation in peritoneal derived macrophages, associated with decreased lipid influx. by Meng Zhang (154027)

MBIC50 and MBEC50 values (µg/mL) of synthesized 1,2,3,5-tetrazine derivatives against bacteria pathogen strains. by Jean Paul Dzoyem (6424445)

Subjects:

Treatment of cancer cells with FL118 significantly decreases BrdU positive cells (proliferative cells) and induces apoptotic markers. by Xiang Ling (307318)

Silencing of SphK1, but not SphK2, decreases HPAEC migration by S1P in wound healing ECIS assay. by Evgeny V. Berdyshev (307465)

Inhibition of PI3K activity decreases uptake of Opa_CEA-expressing gonococci via CEACAM1. by Maike Voges (154488)

T310A mutation decreases TSP50’s ability to interact with NF-κB:IκBα complex and to promote NF-κB signaling. by Yu-Yin Li (323887)

Growth of <i>Spirulina</i> spp. at 450nm for different temperature. by Maha Rehman (17114332)

The IC50 value of Tan in normal esophageal HET-1A cells. by Dong Yang (141041)

Assessment of exoprotein concentration in a 50-mL culture of MH96. by Marion Schoof (11999106)

HPK1-IN-3 decreased T lymphocyte activation. by Min Jeong Ahn (18886882)