EFFECTS OF ADAPTED CANOEING ON THE CARDIOPULMONARY SYSTEM OF PARAPLEGICS by Elizângela Márcia de Carvalho Abreu (6147902)

“…Methods: The study included six paraplegics, five men and one woman, average age of 31.50 ± 7.68 years and mean body mass index of 24.00 ± 1.13 kg/m², level of injury T4 to T9, who underwent training with adapted canoeing for three months. …”

TPMP inhibits mitochondrial respiration and increases glycolytic activity in intact C2C12 cells. by Moustafa Elkalaf (441286)

“…The groups included an untreated control (polarized), 1 μM oligomycin treated (hyperpolarized), 0.5 μM FCCP treated (depolarized) and 1 μM rotenone treated (decreased polarization). Data is expressed as TMRM fluorescence (a.u) means ±95% CI, n = 4, in which each group included 10 wells. *, p = 0.0013; #, p = 0.0094; **, p<0.0001; ##, p = 0.0076; ns, not significant.…”

No inhibition of TrxR1 activity <i>in vitro</i> by addition of SecTRAPs by Karin Anestål (377878)

“…</p>b,<p>TrxR1 activity is given as turnover (min⁻¹) calculated from the decrease at 340 nm detected in a microplate reader assay with 5 nM TrxR1, 0.5 nM-500 nM truncated TrxR1 as SecTRAP, 10 µM Trx, 145 µM Insulin in 50 mM Tris-Cl, 2 mM EDTA, pH 7.4 and 200 µM NADPH.…”

Changes in cell adhesion and in neuronal morphology induced by sAPPα, sAPPβ and sAPP-Fc added to neurons after 1 DIV. by Stéphanie Chasseigneaux (231744)

“…(<b>C–E</b>) Morphometric analysis 96 hours after the addition of sAPPs (50 to 150 nM) to 1DIV primary neurons. (C) At 50 and 100 nM sAPPα and sAPPβ induce a significant decrease of primary dendrite length while at 150 nM, the decrease in primary dendrite length is still significant for sAPPβ only (50 nM: control (Ctrl) vs sAPPα: p<0.0001, control vs sAPPβ: p<0.0001; 100 nM: control vs sAPPα: p<0.0001, control vs sAPPβ: p<0.0001; 150nM: control vs sAPPα: NS, control vs sAPP-Fc: NS, sAPPα vs sAPP-Fc: NS, control vs sAPPβ: p<0.0001). …”

cpFLIPPi-6.4m can report rapid changes in Pi-induced FRET <i>in vivo</i>. by Swayoma Banerjee (816022)

“…Bars represent mean FRET/eCFP ratio taken from ROIs 50–100 μm from the puncture. …”

GFP mRNA and protein suppression in THP-1 cells. by Breanne Landry (138815)

“…<p>(<b>A</b>) Decrease in GFP mRNA levels, and (<b>B</b>) decrease in GFP protein levels (i: based on mean GFP fluorescence and ii: based on GFP-positive cell population). …”

Dose-Response of SB431542 on C2C12 proliferation and differentiation in the presence of TGF-β1. by Chateen Krueger (204755)

“…(B) SB431542 overcame the TGF-β1 inhibition of C2C12 differentiation with an EC50 of 166 nM. At 10 µM SB431542, we observed a slight but reproducible reduction in the percent of MHC positive nuclei.…”

DataSheet_1_Role of fronto-limbic circuit in neuropsychiatric symptoms of dementia: clinical evidence from an exploratory study.docx by Matteo Cotta Ramusino (5139764)

“…Apathy showed predominant involvement of the inferior frontal regions in AD group (a 30% decrease in CT) and of the cingulate cortex in non-AD group (a 50-60% decrease in CT). …”

Lowering membrane negative charge further reduces tubulation ability for the D151N and R154Q mutants. by Tingting Wu (228837)

“…Scale bar: 50 nm. C) Quantifications of tubule diameter and length by BIN1 variants. …”

Quantification and analysis of the RNAi mediated by synthetic siRNAs targeting over 100 human genes by Scott E. Martin (30985)

“…Data is shown as the mean percentage decrease in target mRNA levels observed for four independent parallel transfections (plus SD). …”

Exposure to estrogen or overexpression of Grx1 abolishes L-BOAA induced MMP loss in SH-SY5Y cells. by Uzma Saeed (49670)

Heterogeneous species increases over time due to continuous binding of Aβ42 to the neurites. by Chun-Chieh Chang (491709)

“…This species accounts for at most 10% for both Aβ40 and Aβ42. The green shaded sections represent the percentage of homogeneous Aβ40 in total Aβ40 species, and show the fraction of homogeneous Aβ40 to decrease over time. …”

Effect of sagopilone (SAG) on cell proliferation, tubulin cytoskeleton, cell cycle and apoptosis of lung cancer cells. by Sebastian Winsel (222664)

“…Proliferation was measured with crystal violet assay. Mean IC50 values as measure of the half-maximal growth inhibition and standard deviations are shown. 1B, Immunofluorescence staining of α-tubulin (green) and DNA (red) in A549 lung cancer cells after incubation with either vehicle (0.1% ethanol), 2.5 nM, or 40 nM SAG. …”

Cellular blebbing in U373MG cells induced by NK1R activation is mediated by the Rho/ROCK/MLCK pathway. by John Meshki (36999)

“…Data are representative of three independent experiments. (<b>B</b>) Decrease in cell impedance induced by SP in U373MG cells preincubated with either control, 2.0 µg/ml C3 transferase, 10 µM Y27632 or 50 µM ML9 for 60 min and then stimulated with SP (100 nM). …”

Quantitative Characterization of the Influence of the Nanoscale Morphology of Nanostructured Surfaces on Bacterial Adhesion and Biofilm Formation by Ajay Vikram Singh (204056)

Soy isoflavones genistein and daidzein protect primary cortical cultures from Tat neurotoxicity. by Sheila M. Adams (322032)

“…<p>Primary cortical neurons were exposed to estrogen (0.1, 2.0 and 10 nM), or isoflavones (0.05, 0.2 and 1 µM) 24 hr prior to the start of Tat_1–86 B (50 nM) treatment. …”

Meth Induces Rapid Alkalization of Acidic Organelles, and Changes in Endosomal Structure in Dendritic Cells by Zsolt Tallóczy (86841)

“…<div><p>(A) Morphometric analysis of the decrease in acridine orange staining after 10 min treatment. …”

Supplementary Material for: Changes in migraine symptoms after ischemic stroke: a cohort study by vanderWeerd N. (18602434)

“…Pain intensity change was reported by 18 (35%) patients (50% increase, 50% decrease). Aura symptomatology improved in 4 (11%). …”

Overexpression of miR-105 inhibits tumour cell growth but does not induce apoptosis. by D. Rice Honeywell (442714)

“…<p>(A–B) Tumour cells were transfected with either 50 nM miR-105 (closed squares) or control (open circles) mimics and subsequently seeded into 96-well plates in replicates of 8. …”

Use of GPCR-HIT to show effect of AT₁ receptor activation on CCR2/Gα_i1 proximity. by Mohammed Akli Ayoub (176430)

“…In the presence of AT₁ receptor, logIC₅₀ for AngII inhibiting 100 nM CCL2 = -8.19 ± 0.31.…”