Photochemistry and Photophysics of Charge-Transfer Excited States in Emissive <i>d</i>¹⁰/<i>d</i>⁰ Heterobimetallic Titanocene Tweezer Complexes by Henry C. London (11408928)

“…The coordination of MX decreases Φ_rxn by two to three orders of magnitude. …”

DataSheet_1_Decreased CD73+ Double-Negative T Cells and Elevated Level of Soluble CD73 Correlated With and Predicted Poor Immune Reconstitution in HIV-Infected Patients After Antir... by Xinyue Wang (286629)

Ivermectin significantly decreases <i>L</i>. <i>loa</i> mf in BALB/c mice. by Rene Bilingwe Ayiseh (6900296)

Image_1_IL-12p40/IL-23p40 Blockade With Ustekinumab Decreases the Synovial Inflammatory Infiltrate Through Modulation of Multiple Signaling Pathways Including MAPK-ERK and Wnt.TIF by Renée H. Fiechter (10230473)

“…For some cell types this was even more pronounced at week 24, but clearly synovial inflammation was incompletely resolved. IL-17A and F, TNF, IL-6, IL-8, and IL-12p40 were not significantly downregulated in qPCR analysis of W12 total biopsies, only MMP3 and IL-23p19 were significantly decreased. …”

Lipoarabinomannan in sputum to detect bacterial load and treatment response in patients with pulmonary tuberculosis: Analytic validation and evaluation in two cohorts by Masanori Kawasaki (274320)

“…Declines in sputum LAM concentrations correlated with increases of MGIT TTD in individual patients. There was a 1.29 log₁₀ decrease of sputum LAM concentration, corresponding to an increase of 221 hours for MGIT TTD during the first 14 days of treatment, a treatment duration often used in early bactericidal activity (EBA) trials. …”

Simulated effects of increased pCREB combined with decreased pCaMKIIα on bistability. by Yili Zhang (540283)

“…However, decreasing <i>k</i>_{<i>basalp_CaMKII</i>} by ~50% blocked the bistable switch (red). …”

Complete data. by Jan Víteček (11434774)

“…A tenfold decrease or increase in concentration induced only a 2-fold decrease or increase in clot degradation. …”

Fig 4 - by Jan Víteček (11434774)

“…A tenfold decrease or increase in concentration induced only a 2-fold decrease or increase in clot degradation. …”

Top 10 score drug combinations. by Mengyao Zhou (9266132)

Kaplan-Meier survival curves for overall survival of MBC by highest tertile of IFN-γ signature vs. the lowest two tertiles. by Christina Gillezeau (5348660)

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Study flow diagram. by Christina Gillezeau (5348660)

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Kaplan–Meier survival curves for overall survival of NMIBC by highest tertile of IFN-γ signature vs the lowest two tertiles. by Christina Gillezeau (5348660)

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Sample flow diagram. by Christina Gillezeau (5348660)

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Kaplan-Meier survival curves for overall survival of MIBC by highest tertile of IFN-γ signature vs the lowest two tertiles. by Christina Gillezeau (5348660)

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Kaplan-Meier survival curves for progression-free survival of MIBC by highest tertile of IFN-γ signature vs the lowest two tertiles. by Christina Gillezeau (5348660)

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Characteristics of bladder cancer patients by stage. by Christina Gillezeau (5348660)

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Hazard ratios (HR) and 95% confidence intervals (CI) for the association between INF- γ signature levels and death among bladder cancer patients by stage. by Christina Gillezeau (5348660)

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Mean (standard deviation) of the ratio between T and NT areas of the red fluorescence intensity (561 nm excitation wavelength) used to determine lesion micro-permeability using CLS... by Flaviana Alves Dias (10439927)

Cytotoxicity (as of %Control) IC₅₀ value (mean ±SD in µM) of the tested compounds vs. positive controls Cisplatin and doxorubicin against other malignancy’ cell lines ad... by MohammedBashar Al-Qazzan (22439236)

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

“…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC₅₀ value of 6 nM). Instead, only a subtle shift in the location of this water molecule resulted in a dramatic decrease in the energy of this high-energy hydration site, as shown by the WaterMap analysis combined with microsecond timescale molecular dynamics simulations. …”