Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η⁶-arene)Os(NN)Cl]⁺, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η⁶-arene)Os(N)Cl₂]. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η⁶-arene)Os(NN)Cl]⁺, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η⁶-arene)Os(N)Cl₂]. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η⁶-arene)Os(NN)Cl]⁺, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η⁶-arene)Os(N)Cl₂]. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η⁶-arene)Os(NN)Cl]⁺, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η⁶-arene)Os(N)Cl₂]. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η⁶-arene)Os(NN)Cl]⁺, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η⁶-arene)Os(N)Cl₂]. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η⁶-arene)Os(NN)Cl]⁺, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η⁶-arene)Os(N)Cl₂]. …”

Decreased pMHC avidity and CD8β-independence for functional avidity of D^bNPN3A-primed T cells for D^bNP₃₆₆. by Sophie A. Valkenburg (176257)

Rhodomyrtone decreases expression of inflammatory transcripts by TNF-α+IL-17A stimulated in skin organ cultures. by Julalak Chorachoo (5855852)

“…<p>Skin biopsies were pre-treated with 400 ng/ml rhodomyrtone 6 h before stimulation with 10 ng/ml TNF-α and 20 ng/ml IL-17A. Rhodomyrtone treatment decreases production of <i>DEFB4</i>, <i>IL1B</i>, <i>IL17C</i>, <i>IL36G</i>, <i>LCN2</i>, <i>PI3</i>, <i>S100A7</i>, and <i>S100A8</i> transcripts as measured by qRT-PCR at 72 h. …”

ILC3s decrease in adipose tissue but ILC2s remain the same. by Fred R. Sattler (9338330)

Immunohistochemical detection of myeloperoxidase, CD3 and CD45 in the pancreas during experimental AP. by Sebastian Weis (161447)

JNK inhibitor AS601245 decreased levels of Bim and CC3 proteins and reduced neuronal apoptosis and brain infarct volume in P7 rat after HI. by Deyuan Li (769599)

“…The infarct volume in the AS601245-treated brain was decreased by 58% compared with the DMSO controls (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0132998#pone.0132998.g004" target="_blank">Fig 4I</a>).…”

Immunohistochemical detection and quantification of myeloperoxidase, CD3 and CD45 positive cells in the lung during experimental AP. by Sebastian Weis (161447)

Fig 10 - by Qingzhou Zheng (12936804)

Decrease in adhesion during early development of <i>Dictyostelium discoideum</i>. by Marco Tarantola (102609)

Mutation in poliovirus 3A protein increases viral sensitivity to BFA and decreases recruitment of GBF1 to membranes. by George A. Belov (375765)

Serum IgA levels in CD89 transgenic mice were substantially decreased while IgA production by B lymphocytes was unaffected. by Lijun Xu (195394)

Confirmatory MDS of PVQ-21 items and HOVs from the K-S and SVS-10 instruments. by Oscar Smallenbroek (17509563)

13 thaxtomin A-resistant mutants were isolated from a screen of 10⁷ mutants. by Chloe Casey (14341756)

The J-domain of HSJ1a decreases the protein level of Atx3 through its chaperone binding. by Xue-Chao Gao (220511)

Increased oxidative stress, viral load and decreased survivability of N2a following RIG-I ablation. by Arshed Nazmi (215284)