Inhibition of EGFR-Grb2 interaction by the small tyrosine kinase inhibitor AG1478. by Peter Lanzerstorfer (540769)

“…(B) Time course of the Grb2 contrast change upon EGF stimulation in control and AG1478 pretreated (1, 10 μM) cells (n = 50). Pretreatment with a tyrosine kinase inhibitor leads to a decreased contrast compared to untreated cells. …”

hMSCs inhibit TNF-α secretion from macrophage-like cells more efficiently in the presence of IFN-γ. by Mika Pietilä (332438)

“…<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0031671#s3" target="_blank">Results</a> are represented as a mean±SD of co-cultures of eight different hMSC lines. …”

Overexpression of SATB1 in transformed normal prostate epithelial PZ-HPV-7 cells. by Sanjeev Shukla (106046)

“…SATB1 overexpression resulted in decrease E-cadherin expression and upregulated MMP9 expression. …”

2-DE pattern and relative abundance of proteins in the cotyledon of flooding-stressed soybean plants. by Setsuko Komatsu (422175)

“…Results are presented as the mean ± SE of relative protein intensity for gels from 3 biological replicates (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0065301#pone.0065301.s002" target="_blank">Figure S2</a>). …”

Differential-gene expression due to time in culture. by Jason Lamontagne (2150689)

“…Gene-expression variation was calculated by Z-score, with red indicating an increase in expression compared to the mean across all samples, and blue indicating a decrease in expression. …”

DataSheet_1_The intrinsic variability of the Indonesian Throughflow.pdf by Ryo Furue (11772699)

“…It is found that the annual-mean ITF transport is different by about 1 Sv between the ensemble members at several years. …”

2-DE pattern and relative abundance of proteins in the root of flooding-stressed soybean plants. by Setsuko Komatsu (422175)

“…Results are presented as the mean ± SE of relative protein intensity for gels from 3 biological replicates (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0065301#pone.0065301.s001" target="_blank">Figure S1</a>). …”

Weight gain of mice treated with the SNPs. by Yang Yu (4292)

“…The weight gain decreased in a dose-dependent manner in SNP treated mice, but with no significant difference compared with control group. …”

Age-Related Differences in Test-Retest Reliability in Resting-State Brain Functional Connectivity by Jie Song (60883)

“…By comparing the test-retest reliability of RSFC with and without GSR across scans, we found significantly higher proportion of reliable connections in both groups without GSR, but decreased stability. …”

Effects of acute physical exercise on oxidative stress and inflammatory status in young, sedentary obese subjects by Francesca Accattato (4068385)

“…Thirty sedentary male volunteers, aged 20–45 (mean age 32 ± 7 years), were recruited, divided into 3 groups (normal weight: BMI < 25 kg/m²; overweight to moderate obesity: 25–35 kg/m²; severe obesity: 35–40 kg/m²), and their blood samples collected before and after a 20-min run at ~ 70% of their VO_2max for the measurement of Glutathione Reductase, Glutathione Peroxidase, Superoxide Dismutase, Total Antioxidant Status (TAS) and cytokines (IL-2, IL-4, IL-6, IL-8, IL-10, IL-1α, IL-1β, TNFα, MCP-1, VEGF, IFNγ, EGF). …”

The histone chaperone protein Nucleosome Assembly Protein-1 (hNAP-1) binds HIV-1 Tat and promotes viral transcription-3 by Chiara Vardabasso (88636)

“…HeLa cells were transfected with a specific siRNA against hNAP-1 or a control siRNA, and then transfected with the LTR-luciferase reporter together with Tat (5 and 25 ng). …”

Knockdown of α-actinin-2 prevents spine maturation in response to NMDA receptor activation. by Jennifer L. Hodges (207936)

“…<p><b>A)</b> When α-actinin-2 is knocked down, spines do not shorten or assume a “mushroom” morphology in response to glycine. …”

Table 1_In Vitro biomechanical study of meniscal properties in patients with severe knee osteoarthritis.xlsx by Yuqi Liu (501183)

“…Both tensile and compressive moduli exhibited a stepwise decrease with increasing degeneration. …”

Table 2_In Vitro biomechanical study of meniscal properties in patients with severe knee osteoarthritis.xlsx by Yuqi Liu (501183)

“…Both tensile and compressive moduli exhibited a stepwise decrease with increasing degeneration. …”

Effects of PD-0332991 on BSG cell lines derived from genetically engineered mouse models. by Kelly L. Barton (465812)

“…<p>Cells were treated with PD-0332991 for 48 hours before being harvested for MTT or BrdU assays to assess cell survival and proliferation, respectively. (A) MTT assays (left panel) show minimal cytotoxic activity at doses up to 5µM in cell lines derived from PDGF-B; Ink4a-ARF deficient BSGs. …”

Deletion of <i>Wwox</i> results in defective mammary branching and lobuloalveolar development. by Brent W. Ferguson (167494)

“…<p>(A–B) Representative microphotographs obtained from whole mounts of 12 week virgin <i>BK5 Wwox WT</i> (A) and <i>KO</i> (B) mammary glands. …”

Data_Sheet_1_Tape-Strip Proteomic Profiling of Atopic Dermatitis on Dupilumab Identifies Minimally Invasive Biomarkers.XLSX by Helen He (345966)

“…Using criteria of fold-change>1.5 and FDR < 0.05, 136 proteins significantly decreased after dupilumab treatment, corresponding to an overall mean improvement of 66.2% in the lesional vs. non-lesional AD proteome. …”

<i>Vegf-A</i> and <i>Iex-1</i> expression in hypoxic NIH 3T3 cells. by Akshaar Brahmbhatt (551498)

“…Each bar shows the mean ± SEM of 3 samples per group. Two-way Student <i>t</i>-test with post hoc Bonferroni's correction was performed. …”

TPO antibodies, thyroiditis and serum T4 in Hi-expressor transgenics, Lo-expressor transgenics and WT mice. by Sandra M. McLachlan (308347)

“…<p>The data are shown graphically in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0043517#pone-0043517-g003" target="_blank">Fig. 3</a>. …”

Effects of quercetin and LY294002 on PI3K/Akt/GSK3β Signaling Pathway. by Wei Jiang (14986)

“…The protein levels of total Akt, p-Akt (Ser473), total GSK3β, GSK3β (pY216) and PT205 were quantified. We found that pre-treatment of 5μmol/L quercetin decreased the level of GSK3β (pY216) and increased the levels of p-Akt (Ser473) and PT205. …”