Genomic analysis of the systemic LPS-induced transcriptional response and impact of TNFα inhibition. by Brendon P. Scicluna (295431)

“…Volcano plot analysis of the LPS-induced response in subjects treated with the TNFα antagonist etanercept. Red dots in panels A and B indicate probes that showed a fold-change ≥1.5 or ≤1.5. …”

A Modular System for the Synthesis of Multiplexed Magnetic Resonance Probes by Daniel J. Mastarone (1319805)

“…We have developed a modular architecture for preparing high-relaxivity multiplexed probes utilizing click chemistry. …”

Table_1_FRAGTE2: An Enhanced Algorithm to Pre-Select Closely Related Genomes for Bacterial Species Demarcation.XLS by Jiaqi Zeng (5987465)

“…However, the overall amount of pairs sieved by FRAGTE1 is still large, requiring seriously unaffordable computing cost, especially for large datasets. Here, we present FRAGTE2. Tests on simulated genomes, real genomes, and metagenome-assembled genomes revealed that (i) FRAGTE2 outstandingly reduces ~50–60.10% of the overall amount of pairs sieved by FRAGTE1, dramatically decreasing the computing cost required for whole-genome species demarcation afterward; (ii) FRAGTE2 shows superior sensitivity than FRAGTE1; (iii) FRAGTE2 shows higher specificity than FRAGTE1; and (iv) FRAGTE2 is faster than or comparable with FRAGTE1. …”

Data_Sheet_1_FRAGTE2: An Enhanced Algorithm to Pre-Select Closely Related Genomes for Bacterial Species Demarcation.PDF by Jiaqi Zeng (5987465)

“…However, the overall amount of pairs sieved by FRAGTE1 is still large, requiring seriously unaffordable computing cost, especially for large datasets. Here, we present FRAGTE2. Tests on simulated genomes, real genomes, and metagenome-assembled genomes revealed that (i) FRAGTE2 outstandingly reduces ~50–60.10% of the overall amount of pairs sieved by FRAGTE1, dramatically decreasing the computing cost required for whole-genome species demarcation afterward; (ii) FRAGTE2 shows superior sensitivity than FRAGTE1; (iii) FRAGTE2 shows higher specificity than FRAGTE1; and (iv) FRAGTE2 is faster than or comparable with FRAGTE1. …”

image_2_Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection.tif by Vineel P. Reddy (5169644)

Video_1_A Characterization of Brain-Computer Interface Performance Trade-Offs Using Support Vector Machines and Deep Neural Networks to Decode Movement Intent.MP4 by Nicholas D. Skomrock (5056142)

image_6_Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection.tif by Vineel P. Reddy (5169644)

image_1_Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection.tif by Vineel P. Reddy (5169644)

image_4_Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection.tif by Vineel P. Reddy (5169644)

image_3_Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection.tif by Vineel P. Reddy (5169644)

Effect of sparsifying the simulation data. by Matteo Tiberti (167837)

DataSheet_1_Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related... by Rahul Y. Mahida (11497801)

“…However, AM HSD-1 reductase activity is impaired in patients with sepsis-related ARDS, compared to sepsis patients without ARDS and lobectomy patients (0.075 v 0.882 v 0.967 pM/hr/10⁶ AMs, p=0.004). …”

Pdx1 effects on cell viability and Pdx1 internalization. by Vincenzo Cardinale (781191)

“…When cells were treated with 0.5 μM Pdx1, cell viability significantly decreased after 48 hours in both hBTSCs and HepG2 as observed by Trypan blue exclusion assay (data are means ± SD of 6 experiments; **p< 0.01; ***p< 0.001). …”

An Epigenetic Switch Involving Overlapping Fur and DNA Methylation Optimizes Expression of a Type VI Secretion Gene Cluster by Yannick R. Brunet (211729)

ABCE1 is essential for S phase progression in human cells by Marina Toompuu (2566042)

Uniaxial Extension of Ultrathin Freestanding Polymer Films by R. Konane Bay (5172449)

Data_Sheet_1_Impact of Proinflammatory Cytokines on the Virulence of Uropathogenic Escherichia coli.docx by Ulrik Engelsöy (6683483)

Uniaxial Extension of Ultrathin Freestanding Polymer Films by R. Konane Bay (5172449)

Methylome Analysis in Chickens Immunized with Infectious Laryngotracheitis Vaccine by José A. Carrillo (757240)

Analysis of VEGF-A Regulated Gene Expression in Endothelial Cells to Identify Genes Linked to Angiogenesis by Corban G. Rivera (19353)