SMC-specific knockout of Klf5 (smcKlf5^−/−) exacerbates the progression of Ang II–induced AAA by facilitating ROS formation. by Dong Ma (584680)

The number of Brn3a-expressing cells in retino-collicular co-cultures decreases between DIV4 and DIV12. by Sylvie Voyatzis (332702)

“…(B, C) The density of cells immunoreactive for Brn3a undergoes a reduction of ∼68% between DIV4 and DIV7, and a further decrease of ∼22% between DIV 7 and DIV12. …”

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…Mutation of seven residues to A (I118A, L122A, F125A, Q126A, L232A, I235A, and L239A) markedly decreased the F3-induced inhibition of TASK-1 channels, consistent with the molecular modeling predictions. …”

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…Mutation of seven residues to A (I118A, L122A, F125A, Q126A, L232A, I235A, and L239A) markedly decreased the F3-induced inhibition of TASK-1 channels, consistent with the molecular modeling predictions. …”

Klf5 down-regulation leads to human VSMC senescence. by Dong Ma (584680)

Klf5 expression is down-regulated in the ruptured human and experimental AAA. by Dong Ma (584680)

Final structural equation models for the relationships between the agropastoral system component and connectivity loss caused by a) increases in biomass and greenness (CL-IBG), b)... by Maite Gartzia (669601)

Growth curves (A, strain AWRI R2 (A); B, strain BH8 (B); C, strain Freddo (F)) and accumulated fermentation system mass loss(D, strain A; E, strain B; F, strain F) of <i>S</i>. <i>... by Xiang-yu Sun (748032)

Increased expression of Fz5 receptor matched with a decrease in NeuN immunoreactivity at 16w. by Carlos González-Fernández (2794207)

We define the term “inhibitory reduction prowess” (IRP) as the percentage by which the product formation rate is reduced by from the initial point before inhibitor is introduced to... by J. Roadnight Sheehan (20141887)

Genetic deletion of Bin1 in neurons leads to a reduction in survival but not to neuronal loss in PS19 Hemi or Ncar mice. by Kathleen M. McAvoy (7224863)

The effects of GM-CSF on DMN-induced histopathological changes. by Mrigendra Bir Karmacharya (13607415)

tuning. Percentage of clusters enriched for spatial annotations in networks predicted by GINI as a function of tuning parameter for data from development stage 9–10 and 13–16. As we increase , the number of edges predicted in the network decrease, however, the enrichment of the different clusters stays almost constant.... by Kriti Puniyani (469389)

“…Percentage of clusters enriched for spatial annotations in networks predicted by GINI as a function of tuning parameter for data from development stage 9–10 and 13–16. As we increase , the number of edges predicted in the network decrease, however, the enrichment of the different clusters stays almost constant. …”

Schematic representation of the effects of stepwise bromination of the benzene ring of benzotriazole (Bt), including interdependence of the molecular volume (A) and pK_a (B) of the products with their IC₅₀ for inhibition of protein kinase CK2α: (a) Green arrows follow sequential bromination of the central vicinal C(5)/C(6) atoms, leading to a moderate decrease of pK_a and a large decrease in IC₅₀; (b) Red arrows illustrate the lesser effects of bromination of the peripheral C(4)/C(7) atoms, resulting in a significant decrease of pK_a, with virtually no gain in inhibitory activity; (c) Black lines link products with the same number of bromine atoms, but substantially differing in pK_a and IC₅₀, culminating in the di- and tri-brominated derivatives with inhibitory activities comparable to that of TBBt. by Romualda Wąsik (119538)

Effects of GM-CSF on the DMN-induced inhibition of PPAR-γ expression. by Mrigendra Bir Karmacharya (13607415)

Effects of GM-CSF on DMN-induced TGF-β1 expression. by Mrigendra Bir Karmacharya (13607415)

Western blot analysis of collagen type I, α-SMA, and TGF-β1 in liver. by Mrigendra Bir Karmacharya (13607415)

Effects of GM-CSF on DMN-induced hepatotoxicity. by Mrigendra Bir Karmacharya (13607415)

Effects of GM-CSF on DMN-induced changes in survival and body weights. by Mrigendra Bir Karmacharya (13607415)

Patterns of lifetime use of substances by gender. by Daniel Waiganjo Kinyanjui (15877725)

“…The lifetime prevalence of substance use was 41.5%, while that of alcohol use was 36%. For both, a higher mean neuroticism score [substance use- (AOR 1.05, 95%CI; 1, 1.10: p = 0.013); alcohol use- (AOR 1.04, 95%CI; 0.99, 1.09: p = 0.032)] showed increased odds of lifetime use, while a higher mean agreeableness score [substance use- (AOR 0.99, 95%CI; 0.95, 1.02: p = 0.008); alcohol use- (AOR 0.99, 95%CI; 0.95, 1.02: p = 0.032)] showed decreased odds of lifetime use. …”