بدائل البحث:
a decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
1 decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
peer » peter (توسيع البحث), per (توسيع البحث)
a decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
1 decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
peer » peter (توسيع البحث), per (توسيع البحث)
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Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.
منشور في 2018"…Galactosemia type 2 is an autosomal recessive disorder characterized by the deficiency of galactokinase (GALK) enzyme due to missense mutations in GALK1 gene, which is associated with various manifestations such as hyper galactosemia and formation of cataracts. …"
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22
Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanis...
منشور في 2014"…Upon knockdown of AhR and Nrf2 the MMA(V)-, DMA(V)-, and TMA(V)-mediated induction of both CYP1A1 and NQO1 proteins was significantly decreased. …"
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23
Effects of different diets on glycemic control among patients with type 2 diabetes: A literature review
منشور في 2022"…Background: Globally, type 2 diabetes mellitus (T2DM) is one of the most common diseases, and the incidence is gradually increasing. …"
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Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor.
منشور في 2022"…Precisely, several questions regarding the right combination of drugs, drug modality, and effective dose recommendations pertaining to the use of ICB-based therapy for HER2+ patients remain unanswered. In this study, we use a mathematical modeling-based approach to quantify the growth inhibition of HER2+ breast cancer (BC) cell colonies (ZR75) when treated with anti-HER2; trastuzumab (TZ) and anti-PD-1/PD-L1 (BMS-202) agents. …"
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Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects
منشور في 2019"…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …"
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Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach
منشور في 2017"…Two arginine residues (131 and 203) in the HNF1A protein are highly conserved residues and contribute to the function of the protein. …"
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33
Theoretical and experimental insights into the C-steel aqueous corrosion inhibition at elevated temperatures in 1.0M HCl via multi-carbonyl Gemini cationic surfactants
منشور في 2023"…The Tafel polarization revealed that at 0.1mM of LAPG and MAPG, the corrosion current density (i corr) of CS was reduced to the lowest extent (75.56 and 53.82μAcm-2) compared to 529.3μAcm-2 in the absence of the inhibitors. …"
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Thiostrepton inhibits growth and induces apoptosis by targeting FoxM1/SKP2/MTH1 axis in B-precursor acute lymphoblastic leukemia cells
منشور في 2021"…Thiostrepton led downregulation of FoxM1 accompanied by decreased expression of Aurora kinase A, B, matrix metalloproteinases, and oncogene SKP2 as well as MTH1. …"
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MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS
منشور في 2021"…Nonetheless, CYP3A4, and CYP2D6 were lower in CSCs by 75%, 23%, 43%, 23.8%, and 17%, respectively. …"
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37
Allergenicity of roasted peanuts treated with a non-human digestive protease
منشور في 2015"…Results indicate that alcalase digestion of sonicated peanuts significantly increased protein solubility while decreasing Ara h 1 and Ara h 2 concentrations in both soluble and insoluble portions of peanuts relative to untreated peanuts. …"
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38
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Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation
منشور في 2015"…Furthermore, we found that while both autophagy inhibitors abolished p38 phosphorylation, only CQ led to significant decrease in pERK1/2. Finally, RCE induced DNA damage and reduced mutant p53, two events that preceded autophagy. …"
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40
Tailoring the deposition of MoSe2 on TiO2 nanorods arrays via radiofrequency magnetron sputtering for enhanced photoelectrochemical water splitting
منشور في 2023"…In particular, the sample synthesized by sputtering of MoSe2 for 90 s, i.e., MoSe2@TiO2-90 s, depicted the highest current density (1.86 mA cm−2 at 0.5 V vs. …"
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