Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region حسب Dagenais, Renée

"…Appreciable variability in minor allele frequencies existed both between and within countries of the Middle East and North Africa region. Conclusions CYP2C9 decrease-of-function alleles altered phenytoin pharmacokinetics in patients originating from the Middle East and North Africa region. …"
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Fabrication of fouling resistant Ti3C2Tx (MXene)/cellulose acetate nanocomposite membrane for forward osmosis application حسب Alfahel, Radwan

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Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation حسب Mai S., El-Shoukrofy

"…The two most effective 15-LOX inhibitors, 2a and 2b, exhibited 69 % and 57 % of quercetin's action, respectively. …"
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Synthesis and characterization of nanocrystalline CoFe2O4-zirconia via propylene oxide aided sol-gel method حسب Bhosale R.R.

"…In this study, a Co ferrite/ZrO2 ceramic nanomixture, with a uniform distribution of Co ferrite and ZrO2, was synthesized by the propylene-oxide-assisted sol gel method. …"
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Umbelliferone inhibits spermatogenic defects and testicular injury in lead-intoxicated rats by suppressing oxidative stress and inflammation, and improving Nrf2/HO-1 signaling حسب Alotaibi, Mohammed F.

"…Conclusion: UMB prevents Pb-induced testicular injury by suppressing oxidative damage, inflammation and cell death, and boosting antioxidant defenses, Nrf2/HO-1 signaling and pituitary-gonadal axis. Thus, UMB may represent a protective and cost-effective agent against Pb testicular toxicity, pending further investigations to elucidate other underlying mechanisms.…"
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Characterization of polysulfone/diisopropylamine 1-alkyl-3-methylimidazolium ionic liquid membranes: high pressure gas separation applications حسب Khraisheh M.

"…Thermogravimetric analysis measurement (TGA), differential scanning calorimeter (DSC), dynamic mechanical analysis, and the tensile properties of the membranes are studied in order to optimize the efficiency of separating CO2 from CO2/N2 mixture and CO2/CH4. TGA showed that pure PSF is a highly thermostable polymer, of which the 5% weight loss temperature is above 150 C. …"
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Results from the first culturally tailored, multidisciplinary diabetes education in Lebanese adults with type 2 diabetes: effects on self-care and metabolic outcomes حسب Sukkarieh-Haraty, Ola

"…This pilot-study tested the effect of culturally-tailored education targeting diabetes selfcare on glycemia and cardiovascular risk factors of Lebanese with type 2 diabetes mellitus (T2DM) (n = 27; Age: 61 ± 10 yrs, 59% males, HbA1c: 8.98 ± 1.38%). …"
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Specific bioactive compounds in ginger and apple alleviate hyperglycemia in mice with high fat diet-induced obesity via Nrf2 mediated pathway حسب Sampath, Chethan

"…We hypothesized that phloretin from apple and [6]-gingerol from ginger inhibit formation of AGEs and suppress the receptor for advanced glycation end products (RAGE) via nuclear factor erythroid-2- related-factor-2 (Nrf2)-dependent pathway. Phloretin and [6]-gingerol were supplemented at two different doses to C57BL/6 mice on high fat diet or standard diet for a period of 17 weeks. …"
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Investigational Study for the efficiency of Fe3O4@SiO2 nanoparticles in the Oil Recovery Process using glass micromodel حسب Elhaj, Wamda

"…For the oil recovery process, the Fe3O4 was applied for the inhibition (i.e., decrease) of oil sedimentation, and the SiO2 NPs were applied for wettability alteration and IFT reduction. …"
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BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells. حسب Alhoshani, Ali

"…Venetoclax (VCX) is a selective BCL-2 inhibitor approved for the treatment of leukemia and lymphoma. …"
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A reliable and cost-effective planning framework of rural area hybrid system considering intelligent weather forecasting حسب Abazari, A.

"…Simulation results illustrate that using photovoltaic panels, wind turbine generators, battery energy storage systems, and diesel engine generators (PV/WTG/BESS/DEG) is the most cost-effective strategy resulting in a 96.13% decrease of CO2 emission compared to DEG system at REPmin=97% and LPSPmax=1%. …"
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Effect of reinforcement concentration on the properties of hot extruded Al-Al2O3 composites synthesized through microwave sintering process حسب Reddy, M. Penchal

"…XRD patterns and SEM/EDS mapping images show a uniform distribution of Al2O3 particles in the Al matrix. …"
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Effect of reinforcement concentration on the properties of hot extruded Al-Al2O3 composites synthesized through microwave sintering process حسب Reddya, M. Penchal

"…XRD patterns and SEM/EDS mapping images show a uniform distribution of Al2O3 particles in the Al matrix. …"
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Removal of pharmaceutical and personal care products (PPCPs) pollutants from water by novel TiO2-Coconut Shell Powder (TCNSP) composite حسب Khraisheh, Majeda

"…Photocatlytic removal of three pharmaceutical and personal care products pollutants using novel TiO2–Coconut Shell Powder (TCNSP) composite was investigated. …"
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Effect of zirconia nanotube coating on the hydrophilicity and mechanochemical behavior of zirconium for biomedical applications حسب Nezhad, Erfan Zal

"…In this study, we anodized pure zirconium in an ammonium fluoride and ethylene glycol electrolyte, which produced a coating of ZrO2 nanotubes (NTs). The ZrO2 coated samples were annealed at different temperatures, and the morphology and structure of the coated substrates were studied using XPS, SEM, TEM, EDS, and SAED. …"
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Sulforaphane reduces obesity by reversing leptin resistance. حسب Çakır, Işın

"…The transcription factor nuclear factor erythroid-derived 2-like 2 (NRF2) is the master regulator of the redox homeostasis and plays a critical role in the resolution of inflammation. …"
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TRAINING PRACTICES OF FILIPINO ATHLETES DURING THE EARLY COVID-19 LOCKDOWN حسب Pagaduan, J.C.

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Thiostrepton inhibits growth and induces apoptosis by targeting FoxM1/SKP2/MTH1 axis in B-precursor acute lymphoblastic leukemia cells حسب Kuttikrishnan, Shilpa

"…In the current study, we showed that the downregulation of FoxM1 by its inhibitor thiostrepton inhibited cell viability and induced caspase-dependent apoptosis in a panel of B-pre-ALL cell lines. Thiostrepton led downregulation of FoxM1 accompanied by decreased expression of Aurora kinase A, B, matrix metalloproteinases, and oncogene SKP2 as well as MTH1. …"
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Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO₂ Photocatalytic Nanocomposites Using the Zebrafish Embryo Model. حسب Al-Kandari, Halema

"…However, both nanocomposites should be used with caution at concentration higher than the NOEC (400 mg/L), in particular RGOTi, which significantly (i) caused pericardial and yolk sac edema; (ii) decreased the hatching rate, locomotion, and hematopoietic activities; and (iii) affected the heart rate. …"
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Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via nrf2 pathway in mice with high fat diet-induced obesity حسب Sampath, Chethan

"…We hypothesized that EGCG would mitigate AGEs formation via activating the nuclear factor erythroid-2-related-factor-2 (Nrf2) pathway in a mouse model of high fat diet-induced obesity. …"
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