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MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels.
Published 2021“…Rheumatoid arthritis (RA) is a well-known chronic inflammatory disorder. Two molecular players act in the inflammation balance of the disease: MyD88 (Myeloid differentiation primary response 88) is related to TLR (Toll-like receptors) response and promotes the formation of myddosome complex resulting in increased inflammation; IRAK3 (Interleukin-1 receptor associated kinase 3) acts suppressing the myddosome complex thus decreasing inflammation. …”
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A Model For A Narrow-Cut Fractionating Column
Published 1997“…The model was tested using different top pressures (5-30 psig), different feed temperatures (77-107T) and different reflux ratios (1:1 to 1:3). The most effective variable was found to be top pressure. …”
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Olive Leaves Extract and Oleuropein Improve Insulin Sensitivity in 3T3-L1 Cells and in High-Fat Diet-Treated Rats via PI3K/AkT Signaling Pathway
Published 2023“…In preadipocytes cells, EE 1/100 decreased cell viability and induced apoptosis. …”
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The Impact of Pamam Dendrimers on Her2-Positive Breast Cancer and the Early Stages of Embryogenesis
Published 2020“…PAMAMs exhibited significant anti-cancer effects that were more pronounced with cationic (-NH2) dendrimers, compared to neutral (-OH) or anionic (-COOH) and were greater in cationic G6 compared to cationic G4. Cationic G6 PAMAMs significantly decreased the viability of HER2-positive breast cancer cell lines down to 5.1% in SK-BR3 and to 5.7% in ZR-75 cells (p<0.001), in a dose and time-dependent fashion. …”
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A Modification to Enhance the Survival of the Island FDMA Flap by Adding a Skin Bridge
Published 2021“…We combined Foucher and Holevich characteristics to design a flap that promises to solve the problem. Methods: This is a case series that includes 9 patients where we describe a technique that has the potential to enhance the survival of the first dorsal metacarpal artery (FDMA) flap and decreases the rate of distal necrosis via addition of a 5-mm skin bridge to the pedicle and by avoiding tunneling. …”
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Impact of a pharmacist-delivered discharge and follow-up intervention for patients with acute coronary syndromes in Qatar: A study protocol for a randomised controlled trial
Published 2016“…Introduction: Acute coronary syndrome (ACS) is one of the leading causes of morbidity and mortality worldwide. …”
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A novel index based on planktonic copepod reproductive traits as a tool for marine ecotoxicology studies
Published 2020“…However, the response to Persistent Organic Pollutants (POPs) such as pentachlorophenol (PCP) and 1,2-dichlorobenzene (DCB) differs. In E. affinis, EPR increases with DCB, but HS falls to <1%. …”
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Zebrafish larvae as a model to demonstrate secondary iron overload.
Published 2018“…Deferoxamine treatment of the iron-loaded zebrafish larvae showed a significant decrease in total iron concentration. This study presented a clear evidence of the effectiveness of zebrafish larvae to use as a tool to study iron overload and open the door for studying the efficiency of potential new iron chelating compounds other than commercially available ones. …”
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