HIF-1α knockdown decreases tumor angiogenesis at sites of bone metastases in mice. by Lauren K. Dunn (260121)

<i>Lf</i>^−/− mice demonstrated decreased apoptosis and increased proliferation. by Qiurong Ye (603788)

Complex I activity is increased in cells with elevated NQO1 levels and is decreased by rotenone. by Jiyeong Kim (433042)

Poly I:C stimulation significantly decreased the number of lysozyme positive cells in enteroids. by Julie M. Davies (412514)

Behavioral response to ambiguous conditioned fear cues is decreased in adult neurogenesis-deficient mice. by Lucas R. Glover (3912628)

Retinoic acid improved cell morphology and decreased the number of hypertrophic cells in LT cultures. by Carmen Retana (479628)

“…In LT cultures, ATRA decreased the number of hypertrophic cells (<b>D</b>). …”

Expression of neurotrophins and their receptors was decreased in <i>Slitrk6</i>-deficient inner ear. by Kei-ichi Katayama (257931)

“…<p>(A) Real-time PCR analysis of <i>Bdnf</i>, <i>Ntf3</i>, <i>Ntrk2</i>, and <i>Ntrk3</i> in E14.5 inner ear (includes cochlear and vestibular sensory epithelia, and spiral and vestibular ganglia). The graphs depict mean + SD of 3 independent analyses. The mRNAs of <i>Bdnf</i> and <i>Ntf3</i> were significantly decreased in <i>Slitrk6</i>-deficient inner ear, whereas those of <i>Ntrk2</i> and <i>Ntrk3</i> were not. * <i>p</i><0.05, Student's <i>t</i>-test. …”

The number of prospermatogonia is decreased in <i>Chtf18</i>^−/− neonatal testes. by Karen M. Berkowitz (123502)

rHSP60 decreases viability of B lymphocyte cell line but not macrophage one. by Igor Emiliano L. Souza (18196495)

MMP-9 expression is decreased in LV-shRNA-ADAMTS-1 transduced vessels. by Evelyn C. Nieves Torres (551495)

nLTD decreases the molecular proximity between endogenous spine cofilin and F-actin by Barbara Calabrese (553229)

“…(<b>B</b>) FRET was carried out as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0094787#s2" target="_blank">Methods</a>. …”

Decreasing neural activity in MBONs that suppress PER when activated has modest effects. by Justine Chia (5459294)

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …”

Zebrafish harboring homozygous mutations in <i>gdf6</i> exhibit decreased endurance. by Michèle G. DuVal (278183)

“…</b> Open field tests of average swim velocity during 10 minutes of each hour through a circadian cycle, in tanks replicating lifetime husbandry conditions, show a lower mean movement at night (in either genotype, **p<0.01) but no difference between genotypes in any measure during day (p = 0.247) or night (p = 0.814).…”

Simvastatin decreases cerebral vasospasm of the middle cerebral artery and reduces microthromboemboli after SAH. by Mohammed Sabri (355717)

“…There was no significant difference between pre-SAH or post-SAH simvastatin treated groups as compared to naïve controls in either brain regions quantified (<i>P></i>0.05). All data are mean ± SD.</p>…”

Hsp90 inhibition decreases the adipogenic transcriptional program without any effect on cytotoxicity. by Sébastien Desarzens (547289)

Total tau levels are significantly decreased in the healthy older brains compared to the younger brains. by Shreyasi Chatterjee (3531506)

Etomoxir and orlistat inhibit cell cycle progression and decreased proliferation rate in myeloma cells. by José Manuel Tirado-Vélez (304970)

Increased osteoblastic activity and decreased osteoclastogenesis in TgLRAP cells <i>in vitro</i>. by Naoto Haruyama (487384)

“…Relative ALP activities (<b>A</b>, at day 10) and accumulated calcium amount (<b>B</b>, at day 21) were statistically higher in the TgLRAP cells as compared to the WT (graphs). …”

Aspirin decreases expression of NFκB and β-catenin in colon cancer cells. by Satya Pathi (301408)

“…<p>Decreased p65/p50 in RKO (A) and SW480 (B) cells. Cells were treated for 48 hr with 5 or 10 mM, and whole cell, nuclear and cytosolic extracts were analyzed by western blot analysis as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0048208#s3" target="_blank">Experimental Procedures</a>. …”